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Vegp2 von Ebners gland protein 2 [ Rattus norvegicus (Norway rat) ]

Gene ID: 94106, updated on 10-Jul-2024

Summary

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Symbol
Vegp2provided by RGD
Full Name
von Ebners gland protein 2provided by RGD
Primary source
RGD:620384
See related
EnsemblRapid:ENSRNOG00000074004 AllianceGenome:RGD:620384
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary
Predicted to enable chloride ion binding activity; signaling receptor binding activity; and zinc ion binding activity. Predicted to be involved in retina homeostasis. Predicted to be located in extracellular region. Predicted to be active in extracellular space. Orthologous to several human genes including LCN1 (lipocalin 1). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in Testes (RPKM 5.8), Thymus (RPKM 1.8) and 1 other tissue See more
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Genomic context

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See Vegp2 in Genome Data Viewer
Location:
3p13
Exon count:
10
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 3 NC_086021.1 (29914540..29940231, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 3 NC_051338.1 (9516457..9542088, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 3 NC_005102.4 (4217260..4221330, complement)

Chromosome 3 - NC_086021.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC102547612 Neighboring gene ring finger protein 138, pseudogene 3 Neighboring gene activated RNA polymerase II transcriptional coactivator p15 pseudogene Neighboring gene lipocalin 1 Neighboring gene vomeronasal secretory protein 2-like Neighboring gene ribosomal protein L9, pseudogene 31

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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Related articles in PubMed

  1. Structural organization of the genes for rat von Ebner's gland proteins 1 and 2 reveals their close relationship to lipocalins. Kock K, et al. Eur J Biochem, 1994 May 1. PMID 7514123
  2. Shotgun proteomics reveals specific modulated protein patterns in tears of patients with primary open angle glaucoma naïve to therapy. Pieragostino D, et al. Mol Biosyst, 2013 Jun. PMID 23580065
  3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables small molecule binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in sensory perception of taste IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in extracellular region IEA
Inferred from Electronic Annotation
more info
  
is_active_in extracellular space IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
von Ebner gland protein 2
Names
VEG protein 2
von Ebner gland protein 2-like

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001430153.1 → NP_001417082.1  von Ebner gland protein 2 isoform 2

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000003

  2. NM_053574.2 → NP_446026.1  von Ebner gland protein 2 isoform 1 precursor

    See identical proteins and their annotated locations for NP_446026.1

    Status: PROVISIONAL

    Source sequence(s)
    JAXUCZ010000003
    UniProtKB/Swiss-Prot
    P41244
    UniProtKB/TrEMBL
    R9PXY4
    Related
    ENSRNOP00000041023.4, ENSRNOT00000042910.6
    Conserved Domains (1) summary
    cd19414
    Location:26 → 173
    lipocalin_1_3_4_13-like; lipocalin-1, -3, -4, -13 and similar proteins

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086021.1 Reference GRCr8

    Range
    29914540..29940231 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_039106004.2 → XP_038961932.1  von Ebner gland protein 2 isoform X2

    Conserved Domains (1) summary
    cd19414
    Location:1 → 116
    lipocalin_1_3_4_13-like; lipocalin-1, -3, -4, -13 and similar proteins

  2. XM_039106003.2 → XP_038961931.1  von Ebner gland protein 2 isoform X1

    UniProtKB/TrEMBL
    A6JTH3
    Conserved Domains (1) summary
    cd19414
    Location:7 → 150
    lipocalin_1_3_4_13-like; lipocalin-1, -3, -4, -13 and similar proteins
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P41244.1 GenPept UniProtKB/Swiss-Prot:P41244

Gene LinkOut

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