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These reference sequences exist independently of genome builds. Explain
These reference sequences are curated independently of the genome
annotation cycle, so their versions may not match the RefSeq versions in the current
genome build. Identify version mismatches by comparing the version of the RefSeq in
this section to the one reported in Genomic regions,
transcripts, and products above.
Genomic
-
NG_012101.1 RefSeqGene
- Range
-
5001..18159
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
mRNA and Protein(s)
-
NM_001304441.2 → NP_001291370.1 neutrophil collagenase isoform 2
See identical proteins and their annotated locations for NP_001291370.1
Status: REVIEWED
- Description
- Transcript Variant: This variant (2) differs in the 5' UTR and initiates translation at an alternate start codon compared to variant 1. The encoded isoform (2) is shorter and has a distinct N-terminus compared to isoform 1. Variants 2 and 3 encode the same isoform (2).
- Source sequence(s)
-
AK303388, AL597614, AP000647, AW468376, BC144094, BG213446, J05556
- UniProtKB/TrEMBL
-
B4E0I2
- Conserved Domains (4) summary
-
- cd00094
Location:253 → 441
- HX; Hemopexin-like repeats.; Hemopexin is a heme-binding protein that transports heme to the liver. Hemopexin-like repeats occur in vitronectin and some matrix metalloproteinases family (matrixins). The HX repeats of some matrixins bind tissue inhibitor of ...
- cd04278
Location:84 → 239
- ZnMc_MMP; Zinc-dependent metalloprotease, matrix metalloproteinase (MMP) sub-family. MMPs are responsible for a great deal of pericellular proteolysis of extracellular matrix and cell surface molecules, playing crucial roles in morphogenesis, cell fate ...
- pfam00413
Location:84 → 239
- Peptidase_M10; Matrixin
- pfam01471
Location:8 → 63
- PG_binding_1; Putative peptidoglycan binding domain
-
NM_001304442.2 → NP_001291371.1 neutrophil collagenase isoform 2
See identical proteins and their annotated locations for NP_001291371.1
Status: REVIEWED
- Description
- Transcript Variant: This variant (3) differs in the 5' UTR and initiates translation at an alternate start codon compared to variant 1. The encoded isoform (2) is shorter and has a distinct N-terminus compared to isoform 1. Variants 2 and 3 encode the same isoform (2).
- Source sequence(s)
-
AL597614, AP000647, AW468376, BC144094, BG218770, J05556
- UniProtKB/TrEMBL
-
B4E0I2
- Conserved Domains (4) summary
-
- cd00094
Location:253 → 441
- HX; Hemopexin-like repeats.; Hemopexin is a heme-binding protein that transports heme to the liver. Hemopexin-like repeats occur in vitronectin and some matrix metalloproteinases family (matrixins). The HX repeats of some matrixins bind tissue inhibitor of ...
- cd04278
Location:84 → 239
- ZnMc_MMP; Zinc-dependent metalloprotease, matrix metalloproteinase (MMP) sub-family. MMPs are responsible for a great deal of pericellular proteolysis of extracellular matrix and cell surface molecules, playing crucial roles in morphogenesis, cell fate ...
- pfam00413
Location:84 → 239
- Peptidase_M10; Matrixin
- pfam01471
Location:8 → 63
- PG_binding_1; Putative peptidoglycan binding domain
-
NM_002424.3 → NP_002415.1 neutrophil collagenase isoform 1 preproprotein
See identical proteins and their annotated locations for NP_002415.1
Status: REVIEWED
- Description
- Transcript Variant: This variant (1) represents the shortest transcript and encodes the longer isoform (1).
- Source sequence(s)
-
AP000647, BC074988, DW009698
- Consensus CDS
-
CCDS8320.1
- UniProtKB/Swiss-Prot
- P22894, Q45F99
- UniProtKB/TrEMBL
-
A8K9E4
- Related
- ENSP00000236826.3, ENST00000236826.8
- Conserved Domains (4) summary
-
- cd00094
Location:276 → 464
- HX; Hemopexin-like repeats.; Hemopexin is a heme-binding protein that transports heme to the liver. Hemopexin-like repeats occur in vitronectin and some matrix metalloproteinases family (matrixins). The HX repeats of some matrixins bind tissue inhibitor of ...
- cd04278
Location:107 → 262
- ZnMc_MMP; Zinc-dependent metalloprotease, matrix metalloproteinase (MMP) sub-family. MMPs are responsible for a great deal of pericellular proteolysis of extracellular matrix and cell surface molecules, playing crucial roles in morphogenesis, cell fate ...
- pfam00413
Location:107 → 262
- Peptidase_M10; Matrixin
- pfam01471
Location:29 → 86
- PG_binding_1; Putative peptidoglycan binding domain
The following sections contain reference sequences that belong to a
specific genome build. Explain
This section includes genomic Reference
Sequences (RefSeqs) from all assemblies on which this gene is annotated, such as
RefSeqs for chromosomes and scaffolds (contigs) from both reference and alternate
assemblies. Model RNAs and proteins are also reported here.
Reference GRCh38.p14 Primary Assembly
Genomic
-
NC_000011.10 Reference GRCh38.p14 Primary Assembly
- Range
-
102711796..102724954 complement
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
mRNA and Protein(s)
-
XM_011542834.3 → XP_011541136.1 neutrophil collagenase isoform X1
- UniProtKB/TrEMBL
-
A8K9E4
- Conserved Domains (4) summary
-
- cd00094
Location:285 → 473
- HX; Hemopexin-like repeats.; Hemopexin is a heme-binding protein that transports heme to the liver. Hemopexin-like repeats occur in vitronectin and some matrix metalloproteinases family (matrixins). The HX repeats of some matrixins bind tissue inhibitor of ...
- cd04278
Location:116 → 271
- ZnMc_MMP; Zinc-dependent metalloprotease, matrix metalloproteinase (MMP) sub-family. MMPs are responsible for a great deal of pericellular proteolysis of extracellular matrix and cell surface molecules, playing crucial roles in morphogenesis, cell fate ...
- pfam00413
Location:116 → 271
- Peptidase_M10; Matrixin
- pfam01471
Location:45 → 95
- PG_binding_1; Putative peptidoglycan binding domain
-
XM_011542835.3 → XP_011541137.1 neutrophil collagenase isoform X2
See identical proteins and their annotated locations for XP_011541137.1
- UniProtKB/TrEMBL
-
B4E0I2
- Conserved Domains (4) summary
-
- cd00094
Location:253 → 441
- HX; Hemopexin-like repeats.; Hemopexin is a heme-binding protein that transports heme to the liver. Hemopexin-like repeats occur in vitronectin and some matrix metalloproteinases family (matrixins). The HX repeats of some matrixins bind tissue inhibitor of ...
- cd04278
Location:84 → 239
- ZnMc_MMP; Zinc-dependent metalloprotease, matrix metalloproteinase (MMP) sub-family. MMPs are responsible for a great deal of pericellular proteolysis of extracellular matrix and cell surface molecules, playing crucial roles in morphogenesis, cell fate ...
- pfam00413
Location:84 → 239
- Peptidase_M10; Matrixin
- pfam01471
Location:8 → 63
- PG_binding_1; Putative peptidoglycan binding domain
-
XM_047426965.1 → XP_047282921.1 neutrophil collagenase isoform X2
- UniProtKB/TrEMBL
-
B4E0I2
-
XM_047426966.1 → XP_047282922.1 neutrophil collagenase isoform X3
- UniProtKB/TrEMBL
-
H7C1M3
- Related
- ENSP00000401004.2, ENST00000438475.2
Alternate T2T-CHM13v2.0
Genomic
-
NC_060935.1 Alternate T2T-CHM13v2.0
- Range
-
102713966..102727115 complement
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
mRNA and Protein(s)
-
XM_054368836.1 → XP_054224811.1 neutrophil collagenase isoform X1
- UniProtKB/TrEMBL
-
A8K9E4
-
XM_054368838.1 → XP_054224813.1 neutrophil collagenase isoform X2
- UniProtKB/TrEMBL
-
B4E0I2
-
XM_054368837.1 → XP_054224812.1 neutrophil collagenase isoform X2
- UniProtKB/TrEMBL
-
B4E0I2
-
XM_054368839.1 → XP_054224814.1 neutrophil collagenase isoform X3
- UniProtKB/TrEMBL
-
H7C1M3