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    AMZ2 archaelysin family metallopeptidase 2 [ Homo sapiens (human) ]

    Gene ID: 51321, updated on 10-Dec-2024

    Summary

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    Official Symbol
    AMZ2provided by HGNC
    Official Full Name
    archaelysin family metallopeptidase 2provided by HGNC
    Primary source
    HGNC:HGNC:28041
    See related
    Ensembl:ENSG00000196704 MIM:615169; AllianceGenome:HGNC:28041
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Summary
    The protein encoded by this gene is a zinc metalloprotease that displays some activity against angiotensin-3. The encoded protein is inhibited by the aminopeptidase inhibitor amastatin, as well as by the general inhibitors o-phenanthroline and batimastat. Defects in this gene may be associated with lung tumorigenesis. [provided by RefSeq, Oct 2016]
    Expression
    Broad expression in testis (RPKM 44.9), brain (RPKM 18.1) and 25 other tissues See more
    Orthologs
    mouse all
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    Genomic context

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    See AMZ2 in Genome Data Viewer
    Location:
    17q24.2
    Exon count:
    11
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 17 NC_000017.11 (68206129..68257164)
    RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 17 NC_060941.1 (69082913..69133740)
    RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 17 NC_000017.10 (66202270..66253305)

    Chromosome 17 - NC_000017.11Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC105371870 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr17:66165711-66166210 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 12637 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 12638 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 12639 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr17:66180501-66181101 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 12640 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 12641 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 8890 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 8891 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 8892 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr17:66196439-66197255 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 8893 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 8894 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 8895 Neighboring gene Rho GTPase activating protein 27 pseudogene 2 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr17:66224773-66225658 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 12642 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 12643 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 8896 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr17:66242704-66243250 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr17:66243251-66243796 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 8897 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 8898 Neighboring gene solute carrier family 16 member 6 Neighboring gene arylsulfatase G Neighboring gene ReSE screen-validated silencer GRCh37_chr17:66287460-66287634 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 12644 Neighboring gene Sharpr-MPRA regulatory region 10227 Neighboring gene H3K27ac hESC enhancer GRCh37_chr17:66340482-66340982 Neighboring gene H3K27ac hESC enhancer GRCh37_chr17:66340983-66341483 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 12645 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 12646 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 12647 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr17:66374359-66374878 Neighboring gene MPRA-validated peak2959 silencer Neighboring gene tRNA-undetermined (NNN) 5-1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: HPA RNA-seq normal tissues
    • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
    • BioProject: PRJEB4337
    • Publication: PMID 24309898
    • Analysis date: Wed Apr 4 07:08:55 2018

    Bibliography

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    Related articles in PubMed

    1. Refined-mapping of the novel TSG within the 17q24.3 chromosomal region in non-small cell lung cancer samples. Huang W, et al. Oncol Lett, 2016 Sep. PMID 27602123, Free PMC Article
    2. Sequences in the cytoplasmic tail of SARS-CoV-2 Spike facilitate expression at the cell surface and syncytia formation. Cattin-Ortolá J, et al. Nat Commun, 2021 Sep 9. PMID 34504087, Free PMC Article
    3. CAMK2D serves as a molecular scaffold for RNF8-MAD2 complex to induce mitotic checkpoint in glioma. Chuah YH, et al. Cell Death Differ, 2023 Aug. PMID 37468549, Free PMC Article
    4. Cloning and functional analysis of cDNAs with open reading frames for 300 previously undefined genes expressed in CD34+ hematopoietic stem/progenitor cells. Zhang QH, et al. Genome Res, 2000 Oct. PMID 11042152, Free PMC Article
    5. The variant Polycomb Repressor Complex 1 component PCGF1 interacts with a pluripotency sub-network that includes DPPA4, a regulator of embryogenesis. Oliviero G, et al. Sci Rep, 2015 Dec 21. PMID 26687479, Free PMC Article

    See all (17) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator)
      Title: Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.
    Submit: New GeneRIF Correction

    Phenotypes

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    Find tests for this gene in the NIH Genetic Testing Registry (GTR)

    Review eQTL and phenotype association data in this region using PheGenI

    Variation

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    See variants in ClinVar

    See studies and variants in dbVar

    See Variation Viewer (GRCh37.p13)

    See Variation Viewer (GRCh38)

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by GOA

    Function Evidence Code Pubs
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables metallopeptidase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in proteolysis IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  

    General protein information

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    Preferred Names
    archaemetzincin-2
    Names
    archaemetzincins-2
    archeobacterial metalloproteinase-like protein 2
    NP_001028741.1
    NP_001028742.1
    NP_001028743.1
    NP_001028744.1
    NP_001028746.1
    NP_001275983.1
    NP_001275985.1
    NP_001333400.1
    NP_001333401.1
    NP_001333402.1
    NP_001333403.1
    NP_001333404.1
    NP_001333405.1
    NP_001333406.1
    NP_001333407.1
    NP_001333408.1
    NP_001333409.1
    NP_001333410.1
    NP_001333411.1
    NP_001333412.1
    NP_001333413.1
    NP_001333414.1
    NP_057711.3
    XP_024306554.1
    XP_024306555.1
    XP_024306556.1
    XP_047292166.1
    XP_047292167.1
    XP_054172343.1
    XP_054172344.1
    XP_054172345.1
    XP_054172346.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    Genomic

    1. NG_051827.1 RefSeqGene

      Range
      46915..56027
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001033569.2 → NP_001028741.1  archaemetzincin-2 isoform 1

      See identical proteins and their annotated locations for NP_001028741.1

      Status: REVIEWED

      Description
      Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Variants 1-5 and 7-17 all encode the same isoform (1).
      Source sequence(s)
      AC005332, BE543044, BF978559
      Consensus CDS
      CCDS11674.1
      UniProtKB/Swiss-Prot
      A6NLD9, B3KR44, Q5XKF1, Q86W34, Q9NZE2
      Related
      ENSP00000376481.2, ENST00000392720.6
      Conserved Domains (1) summary
      cd11375
      Location:89 → 297
      Peptidase_M54; Peptidase family M54, also called archaemetzincins or archaelysins

    2. NM_001033570.2 → NP_001028742.1  archaemetzincin-2 isoform 1

      See identical proteins and their annotated locations for NP_001028742.1

      Status: REVIEWED

      Description
      Transcript Variant: This variant (3) differs in the 5' UTR compared to variant 1. Variants 1-5 and 7-17 all encode the same isoform (1).
      Source sequence(s)
      AC005332, BE543044, CN278872
      Consensus CDS
      CCDS11674.1
      UniProtKB/Swiss-Prot
      A6NLD9, B3KR44, Q5XKF1, Q86W34, Q9NZE2
      Conserved Domains (1) summary
      cd11375
      Location:89 → 297
      Peptidase_M54; Peptidase family M54, also called archaemetzincins or archaelysins

    3. NM_001033571.1 → NP_001028743.1  archaemetzincin-2 isoform 1

      See identical proteins and their annotated locations for NP_001028743.1

      Status: REVIEWED

      Description
      Transcript Variant: This variant (4) differs in the 5' UTR compared to variant 1. Variants 1-5 and 7-17 all encode the same isoform (1).
      Source sequence(s)
      AC005332, BE543044, BF978559, BM450564
      Consensus CDS
      CCDS11674.1
      UniProtKB/Swiss-Prot
      A6NLD9, B3KR44, Q5XKF1, Q86W34, Q9NZE2
      Conserved Domains (1) summary
      cd11375
      Location:89 → 297
      Peptidase_M54; Peptidase family M54, also called archaemetzincins or archaelysins

    4. NM_001033572.1 → NP_001028744.1  archaemetzincin-2 isoform 1

      See identical proteins and their annotated locations for NP_001028744.1

      Status: REVIEWED

      Description
      Transcript Variant: This variant (5) differs in the 5' UTR compared to variant 1. Variants 1-5 and 7-17 all encode the same isoform (1).
      Source sequence(s)
      AC005332, BE543044, BF978559
      Consensus CDS
      CCDS11674.1
      UniProtKB/Swiss-Prot
      A6NLD9, B3KR44, Q5XKF1, Q86W34, Q9NZE2
      Related
      ENSP00000463012.1, ENST00000580753.5
      Conserved Domains (1) summary
      cd11375
      Location:89 → 297
      Peptidase_M54; Peptidase family M54, also called archaemetzincins or archaelysins

    5. NM_001033574.2 → NP_001028746.1  archaemetzincin-2 isoform 2

      Status: REVIEWED

      Description
      Transcript Variant: This variant (6) lacks an alternate in-frame exon compared to variant 1. The resulting isoform (2) has the same N- and C-termini but is shorter compared to isoform 1. Variants 2 and 18 both encode the same isoform (2).
      Source sequence(s)
      AC005332, AK126146, AW028610
      Consensus CDS
      CCDS32714.1
      UniProtKB/Swiss-Prot
      Q86W34
      Related
      ENSP00000352831.4, ENST00000359783.8
      Conserved Domains (1) summary
      cd11375
      Location:95 → 239
      Peptidase_M54; Peptidase family M54, also called archaemetzincins or archaelysins

    6. NM_001289054.2 → NP_001275983.1  archaemetzincin-2 isoform 1

      See identical proteins and their annotated locations for NP_001275983.1

      Status: REVIEWED

      Description
      Transcript Variant: This variant (7) differs in the 5' UTR compared to variant 1. Variants 1-5 and 7-17 all encode the same isoform (1).
      Source sequence(s)
      AC005332, BC050709
      Consensus CDS
      CCDS11674.1
      UniProtKB/Swiss-Prot
      A6NLD9, B3KR44, Q5XKF1, Q86W34, Q9NZE2
      Conserved Domains (1) summary
      cd11375
      Location:89 → 297
      Peptidase_M54; Peptidase family M54, also called archaemetzincins or archaelysins

    7. NM_001289056.2 → NP_001275985.1  archaemetzincin-2 isoform 1

      See identical proteins and their annotated locations for NP_001275985.1

      Status: REVIEWED

      Description
      Transcript Variant: This variant (8) differs in the 5' UTR compared to variant 1. Variants 1-5 and 7-17 all encode the same isoform (1).
      Source sequence(s)
      AC005332, AF208856, BC050709, CN278874
      Consensus CDS
      CCDS11674.1
      UniProtKB/Swiss-Prot
      A6NLD9, B3KR44, Q5XKF1, Q86W34, Q9NZE2
      Related
      ENSP00000483162.1, ENST00000612294.4
      Conserved Domains (1) summary
      cd11375
      Location:89 → 297
      Peptidase_M54; Peptidase family M54, also called archaemetzincins or archaelysins

    8. NM_001346471.1 → NP_001333400.1  archaemetzincin-2 isoform 1

      Status: REVIEWED

      Description
      Transcript Variant: This variant (9), as well as variants 1-5, 7-8, and 10-17, encodes isoform 1.
      Source sequence(s)
      AC005332
      Consensus CDS
      CCDS11674.1
      UniProtKB/Swiss-Prot
      A6NLD9, B3KR44, Q5XKF1, Q86W34, Q9NZE2
      Related
      ENSP00000464635.1, ENST00000577985.5
      Conserved Domains (1) summary
      cd11375
      Location:89 → 297
      Peptidase_M54; Peptidase family M54, also called archaemetzincins or archaelysins

    9. NM_001346472.1 → NP_001333401.1  archaemetzincin-2 isoform 1

      Status: REVIEWED

      Description
      Transcript Variant: This variant (10), as well as variants 1-5, 7-9, and 11-17, encodes isoform 1.
      Source sequence(s)
      AC005332
      Consensus CDS
      CCDS11674.1
      UniProtKB/Swiss-Prot
      A6NLD9, B3KR44, Q5XKF1, Q86W34, Q9NZE2
      Conserved Domains (1) summary
      cd11375
      Location:89 → 297
      Peptidase_M54; Peptidase family M54, also called archaemetzincins or archaelysins

    10. NM_001346473.1 → NP_001333402.1  archaemetzincin-2 isoform 1

      Status: REVIEWED

      Description
      Transcript Variant: This variant (11), as well as variants 1-5, 7-10, and 12-17, encodes isoform 1.
      Source sequence(s)
      AC005332
      Consensus CDS
      CCDS11674.1
      UniProtKB/Swiss-Prot
      A6NLD9, B3KR44, Q5XKF1, Q86W34, Q9NZE2
      Related
      ENSP00000501934.1, ENST00000674770.2
      Conserved Domains (1) summary
      cd11375
      Location:89 → 297
      Peptidase_M54; Peptidase family M54, also called archaemetzincins or archaelysins

    11. NM_001346474.2 → NP_001333403.1  archaemetzincin-2 isoform 1

      Status: REVIEWED

      Description
      Transcript Variant: This variant (12), as well as variants 1-5, 7-11, and 13-17, encodes isoform 1.
      Source sequence(s)
      AC005332
      Consensus CDS
      CCDS11674.1
      UniProtKB/Swiss-Prot
      A6NLD9, B3KR44, Q5XKF1, Q86W34, Q9NZE2
      Conserved Domains (1) summary
      cd11375
      Location:89 → 297
      Peptidase_M54; Peptidase family M54, also called archaemetzincins or archaelysins

    12. NM_001346475.2 → NP_001333404.1  archaemetzincin-2 isoform 1

      Status: REVIEWED

      Description
      Transcript Variant: This variant (13), as well as variants 1-5, 7-12, and 14-17, encodes isoform 1.
      Source sequence(s)
      AC005332
      Consensus CDS
      CCDS11674.1
      UniProtKB/Swiss-Prot
      A6NLD9, B3KR44, Q5XKF1, Q86W34, Q9NZE2
      Conserved Domains (1) summary
      cd11375
      Location:89 → 297
      Peptidase_M54; Peptidase family M54, also called archaemetzincins or archaelysins

    13. NM_001346476.2 → NP_001333405.1  archaemetzincin-2 isoform 1

      Status: REVIEWED

      Description
      Transcript Variant: This variant (14), as well as variants 1-5, 7-13, and 15-17, encodes isoform 1.
      Source sequence(s)
      AC005332
      Consensus CDS
      CCDS11674.1
      UniProtKB/Swiss-Prot
      A6NLD9, B3KR44, Q5XKF1, Q86W34, Q9NZE2
      Conserved Domains (1) summary
      cd11375
      Location:89 → 297
      Peptidase_M54; Peptidase family M54, also called archaemetzincins or archaelysins

    14. NM_001346477.2 → NP_001333406.1  archaemetzincin-2 isoform 1

      Status: REVIEWED

      Description
      Transcript Variant: This variant (15), as well as variants 1-5, 7-14, and 16-17, encodes isoform 1.
      Source sequence(s)
      AC005332
      Consensus CDS
      CCDS11674.1
      UniProtKB/Swiss-Prot
      A6NLD9, B3KR44, Q5XKF1, Q86W34, Q9NZE2
      Related
      ENSP00000464133.1, ENST00000577866.5
      Conserved Domains (1) summary
      cd11375
      Location:89 → 297
      Peptidase_M54; Peptidase family M54, also called archaemetzincins or archaelysins

    15. NM_001346478.2 → NP_001333407.1  archaemetzincin-2 isoform 1

      Status: REVIEWED

      Description
      Transcript Variant: This variant (16), as well as variants 1-5, 7-15, and 17, encodes isoform 1.
      Source sequence(s)
      AC005332
      Consensus CDS
      CCDS11674.1
      UniProtKB/Swiss-Prot
      A6NLD9, B3KR44, Q5XKF1, Q86W34, Q9NZE2
      Conserved Domains (1) summary
      cd11375
      Location:89 → 297
      Peptidase_M54; Peptidase family M54, also called archaemetzincins or archaelysins

    16. NM_001346479.2 → NP_001333408.1  archaemetzincin-2 isoform 1

      Status: REVIEWED

      Description
      Transcript Variant: This variant (17), as well as variants 1-5 and 7-16, encodes isoform 1.
      Source sequence(s)
      AC005332
      Consensus CDS
      CCDS11674.1
      UniProtKB/Swiss-Prot
      A6NLD9, B3KR44, Q5XKF1, Q86W34, Q9NZE2
      Conserved Domains (1) summary
      cd11375
      Location:89 → 297
      Peptidase_M54; Peptidase family M54, also called archaemetzincins or archaelysins

    17. NM_001346480.1 → NP_001333409.1  archaemetzincin-2 isoform 2

      Status: REVIEWED

      Description
      Transcript Variant: This variant (18), as well as variant 6, encodes isoform 2.
      Source sequence(s)
      AC005332
      Consensus CDS
      CCDS32714.1
      UniProtKB/Swiss-Prot
      Q86W34

    18. NM_001346481.1 → NP_001333410.1  archaemetzincin-2 isoform 3

      Status: REVIEWED

      Description
      Transcript Variant: This variant (19), as well as variants 20-22, encodes isoform 3.
      Source sequence(s)
      AC005332
      Conserved Domains (1) summary
      cd11375
      Location:69 → 263
      Peptidase_M54; Peptidase family M54, also called archaemetzincins or archaelysins

    19. NM_001346482.1 → NP_001333411.1  archaemetzincin-2 isoform 3

      Status: REVIEWED

      Description
      Transcript Variant: This variant (20), as well as variants 19 and 21-22, encodes isoform 3.
      Source sequence(s)
      AC005332
      Conserved Domains (1) summary
      cd11375
      Location:69 → 263
      Peptidase_M54; Peptidase family M54, also called archaemetzincins or archaelysins

    20. NM_001346483.2 → NP_001333412.1  archaemetzincin-2 isoform 3

      Status: REVIEWED

      Description
      Transcript Variant: This variant (21), as well as variants 19-20 and 22, encodes isoform 3.
      Source sequence(s)
      AC005332
      Conserved Domains (1) summary
      cd11375
      Location:69 → 263
      Peptidase_M54; Peptidase family M54, also called archaemetzincins or archaelysins

    21. NM_001346484.2 → NP_001333413.1  archaemetzincin-2 isoform 3

      Status: REVIEWED

      Description
      Transcript Variant: This variant (22), as well as variants 19-21, encodes isoform 3.
      Source sequence(s)
      AC005332
      Conserved Domains (1) summary
      cd11375
      Location:69 → 263
      Peptidase_M54; Peptidase family M54, also called archaemetzincins or archaelysins

    22. NM_001346485.2 → NP_001333414.1  archaemetzincin-2 isoform 4

      Status: REVIEWED

      Source sequence(s)
      AC005332

    23. NM_016627.5 → NP_057711.3  archaemetzincin-2 isoform 1

      See identical proteins and their annotated locations for NP_057711.3

      Status: REVIEWED

      Description
      Transcript Variant: This variant (1) encodes the longest isoform (1). Variants 1-5 and 7-17 all encode the same isoform (1).
      Source sequence(s)
      AK126146, BQ432895
      Consensus CDS
      CCDS11674.1
      UniProtKB/Swiss-Prot
      A6NLD9, B3KR44, Q5XKF1, Q86W34, Q9NZE2
      Related
      ENSP00000352976.3, ENST00000359904.8
      Conserved Domains (1) summary
      cd11375
      Location:89 → 297
      Peptidase_M54; Peptidase family M54, also called archaemetzincins or archaelysins

    RNA

    1. NR_144442.2 RNA Sequence

      Status: REVIEWED

      Source sequence(s)
      AC005332

    2. NR_144443.2 RNA Sequence

      Status: REVIEWED

      Source sequence(s)
      AC005332

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000017.11 Reference GRCh38.p14 Primary Assembly

      Range
      68206129..68257164
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_024450788.2 → XP_024306556.1  archaemetzincin-2 isoform X1

      UniProtKB/Swiss-Prot
      A6NLD9, B3KR44, Q5XKF1, Q86W34, Q9NZE2
      Conserved Domains (1) summary
      cd11375
      Location:89 → 297
      Peptidase_M54; Peptidase family M54, also called archaemetzincins or archaelysins

    2. XM_047436210.1 → XP_047292166.1  archaemetzincin-2 isoform X1

      UniProtKB/Swiss-Prot
      A6NLD9, B3KR44, Q5XKF1, Q86W34, Q9NZE2

    3. XM_024450786.2 → XP_024306554.1  archaemetzincin-2 isoform X1

      UniProtKB/Swiss-Prot
      A6NLD9, B3KR44, Q5XKF1, Q86W34, Q9NZE2
      Conserved Domains (1) summary
      cd11375
      Location:89 → 297
      Peptidase_M54; Peptidase family M54, also called archaemetzincins or archaelysins

    4. XM_024450787.2 → XP_024306555.1  archaemetzincin-2 isoform X1

      UniProtKB/Swiss-Prot
      A6NLD9, B3KR44, Q5XKF1, Q86W34, Q9NZE2
      Conserved Domains (1) summary
      cd11375
      Location:89 → 297
      Peptidase_M54; Peptidase family M54, also called archaemetzincins or archaelysins

    5. XM_047436211.1 → XP_047292167.1  archaemetzincin-2 isoform X2

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060941.1 Alternate T2T-CHM13v2.0

      Range
      69082913..69133740
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_054316368.1 → XP_054172343.1  archaemetzincin-2 isoform X1

    2. XM_054316369.1 → XP_054172344.1  archaemetzincin-2 isoform X1

    3. XM_054316370.1 → XP_054172345.1  archaemetzincin-2 isoform X1

    4. XM_054316371.1 → XP_054172346.1  archaemetzincin-2 isoform X2

    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q86W34.2 GenPept UniProtKB/Swiss-Prot:Q86W34

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