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    LINC01615 long intergenic non-protein coding RNA 1615 [ Homo sapiens (human) ]

    Gene ID: 101929484, updated on 19-Sep-2024

    Summary

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    Official Symbol
    LINC01615provided by HGNC
    Official Full Name
    long intergenic non-protein coding RNA 1615provided by HGNC
    Primary source
    HGNC:HGNC:51898
    See related
    Ensembl:ENSG00000223485 AllianceGenome:HGNC:51898
    Gene type
    ncRNA
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Expression
    Low expression observed in reference dataset See more
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    Genomic context

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    See LINC01615 in Genome Data Viewer
    Location:
    6q27
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 6 NC_000006.12 (169158092..169162989, complement)
    RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 6 NC_060930.1 (170509617..170514514, complement)
    RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 6 NC_000006.11 (169558187..169563084, complement)

    Chromosome 6 - NC_000006.12Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC102724357 Neighboring gene CDK7 strongly-dependent group 2 enhancer GRCh37_chr6:169469909-169471108 Neighboring gene uncharacterized LOC124901469 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr6:169576328-169576828 Neighboring gene long intergenic non-protein coding RNA 2544 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr6:169585397-169585896 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr6:169587933-169588434 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr6:169588435-169588934 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 17794 Neighboring gene THBS2 antisense RNA 1 Neighboring gene CDK7 strongly-dependent group 2 enhancer GRCh37_chr6:169624128-169625327 Neighboring gene uncharacterized LOC124901470 Neighboring gene thrombospondin 2

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: HPA RNA-seq normal tissues HPA RNA-seq normal tissues
    • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
    • BioProject: PRJEB4337
    • Publication: PMID 24309898
    • Analysis date: Wed Apr 4 07:08:55 2018

    Bibliography

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    Related articles in PubMed

    1. LINC01615 activates ZEB2 through competitively binding with miR-3653-3p to promote the carcinogenesis of colon cancer cells. Hu Z, et al. Cell Cycle, 2022 Feb. PMID 34965191, Free PMC Article
    2. Identification of LINC01615 as potential metastasis-related long noncoding RNA in hepatocellular carcinoma. Ji D, et al. J Cell Physiol, 2019 Aug. PMID 30556902
    3. Identification of intrahepatic cholangiocarcinoma related genes by comparison with normal liver tissues using expressed sequence tags. Wang AG, et al. Biochem Biophys Res Commun, 2006 Jul 7. PMID 16712791

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. LINC01615 activates ZEB2 through competitively binding with miR-3653-3p to promote the carcinogenesis of colon cancer cells.
      Title: LINC01615 activates ZEB2 through competitively binding with miR-3653-3p to promote the carcinogenesis of colon cancer cells.
    2. LINC01615 had 72 coexpressed genes, and we carried out the gene ontology (GO) term enrichment for these protein-coding genes
      Title: Identification of LINC01615 as potential metastasis-related long noncoding RNA in hepatocellular carcinoma.
    Submit: New GeneRIF Correction

    Phenotypes

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    Review eQTL and phenotype association data in this region using PheGenI

    Variation

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    See variants in ClinVar

    See studies and variants in dbVar

    See Variation Viewer (GRCh37.p13)

    See Variation Viewer (GRCh38)

    Genotypes

    General gene information

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    Other Names

    • RP11-417E7.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    RNA

    1. NR_132622.1 RNA Sequence

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longer transcript.
      Source sequence(s)
      AL136129, CB123670, CB162840

    2. NR_132623.1 RNA Sequence

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) lacks three exons and includes one alternate exon, compared to variant 1.
      Source sequence(s)
      CB123670, HY055819
      Related
      ENST00000439703.1

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000006.12 Reference GRCh38.p14 Primary Assembly

      Range
      169158092..169162989 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060930.1 Alternate T2T-CHM13v2.0

      Range
      170509617..170514514 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein
    Heading Accession and Version

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