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    Krt82 keratin 82 [ Mus musculus (house mouse) ]

    Gene ID: 114566, updated on 2-Nov-2024

    Summary

    Official Symbol
    Krt82provided by MGI
    Official Full Name
    keratin 82provided by MGI
    Primary source
    MGI:MGI:2149248
    See related
    Ensembl:ENSMUSG00000049548 AllianceGenome:MGI:2149248
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Krt2-20
    Summary
    Predicted to be a structural constituent of skin epidermis. Predicted to be involved in intermediate filament organization and keratinization. Predicted to be active in keratin filament. Is expressed in hair cuticle and skin. Orthologous to human KRT82 (keratin 82). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Low expression observed in reference dataset See more
    Orthologs
    NEW
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    Genomic context

    See Krt82 in Genome Data Viewer
    Location:
    15 F2; 15 56.9 cM
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 15 NC_000081.7 (101449651..101459094, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 15 NC_000081.6 (101541216..101550659, complement)

    Chromosome 15 - NC_000081.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 53914 Neighboring gene keratin 85 Neighboring gene STARR-seq mESC enhancer starr_39799 Neighboring gene keratin 84 Neighboring gene keratin 90 Neighboring gene keratin 75

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (2) 
    • Targeted (1) 

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Clone Names

    • MGC124293

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables structural constituent of skin epidermis IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Process Evidence Code Pubs
    involved_in intermediate filament organization IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in keratinization IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    is_active_in keratin filament IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in keratin filament ISO
    Inferred from Sequence Orthology
    more info
     
    located_in keratin filament NAS
    Non-traceable Author Statement
    more info
    PubMed 

    General protein information

    Preferred Names
    keratin, type II cuticular Hb2
    Names
    K82
    keratin complex 2, basic, gene 20
    type II hair keratin Hb2
    type-II keratin Kb22

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_053249.3NP_444479.2  keratin, type II cuticular Hb2

      See identical proteins and their annotated locations for NP_444479.2

      Status: VALIDATED

      Source sequence(s)
      AA607752, BC108971
      Consensus CDS
      CCDS27854.1
      UniProtKB/Swiss-Prot
      Q32MV2, Q99M74
      Related
      ENSMUSP00000023713.8, ENSMUST00000023713.10
      Conserved Domains (2) summary
      pfam00038
      Location:118428
      Filament; Intermediate filament protein
      pfam16208
      Location:16114
      Keratin_2_head; Keratin type II head

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000081.7 Reference GRCm39 C57BL/6J

      Range
      101449651..101459094 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)