Sec31b SEC31 homolog B, COPII coat complex component [Mus musculus (house mouse)] - Gene

Summary

Official Symbol: Sec31bprovided by MGI
Official Full Name: SEC31 homolog B, COPII coat complex componentprovided by MGI
Primary source: MGI:MGI:2685187
See related: Ensembl:ENSMUSG00000051984 AllianceGenome:MGI:2685187
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Mus musculus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as: Gm341; Sec31l2
Summary: Predicted to enable structural molecule activity. Predicted to be involved in COPII-coated vesicle cargo loading; endoplasmic reticulum organization; and intracellular protein transport. Predicted to act upstream of or within protein transport and vesicle-mediated transport. Predicted to be located in cytoplasmic vesicle; endoplasmic reticulum; and membrane. Predicted to be part of COPII vesicle coat. Predicted to be active in endoplasmic reticulum exit site. Orthologous to human SEC31B (SEC31 homolog B, COPII coat complex component). [provided by Alliance of Genome Resources, Apr 2022]
Expression: Broad expression in heart adult (RPKM 6.7), mammary gland adult (RPKM 5.3) and 19 other tissues See more
Orthologs: human all
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Genomic context

Location:: 19 C3; 19 37.98 cM

Exon count:: 26

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCm39 (GCF_000001635.27)	19	NC_000085.7 (44505396..44534287, complement)
108.20200622	previous assembly	GRCm38.p6 (GCF_000001635.26)	19	NC_000085.6 (44516957..44545848, complement)

Chromosome 19 - NC_000085.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Mouse ENCODE transcriptome data
Description: RNA profiling data sets generated by the Mouse ENCODE project.
BioProject: PRJNA66167
Publication: PMID 25409824
Analysis date: n/a

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics (MGI)

Endonuclease-mediated (1)

Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Markers

MARC_21710-21711:1036508963:1 (e-PCR)
- UniSTS:268615

Gene Ontology Provided by MGI

Function	Evidence Code	Pubs
enables structural molecule activity	IBA Inferred from Biological aspect of Ancestor more info

Process	Evidence Code	Pubs
involved_in COPII-coated vesicle cargo loading	IBA Inferred from Biological aspect of Ancestor more info
involved_in endoplasmic reticulum organization	IBA Inferred from Biological aspect of Ancestor more info
involved_in endoplasmic reticulum to Golgi vesicle-mediated transport	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within protein transport	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within vesicle-mediated transport	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
part_of COPII vesicle coat	IBA Inferred from Biological aspect of Ancestor more info
located_in cytoplasm	IEA Inferred from Electronic Annotation more info
located_in cytoplasmic vesicle	IEA Inferred from Electronic Annotation more info
located_in endoplasmic reticulum	IEA Inferred from Electronic Annotation more info
is_active_in endoplasmic reticulum exit site	IBA Inferred from Biological aspect of Ancestor more info
located_in membrane	IEA Inferred from Electronic Annotation more info
part_of vesicle coat	ISO Inferred from Sequence Orthology more info	PubMed

General protein information

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Preferred Names: protein transport protein Sec31B

Names: SEC31-like 2; SEC31-like protein 2; SEC31-related protein B; Sec31 homolog B

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001033343.1 → NP_001028515.1 protein transport protein Sec31B

See identical proteins and their annotated locations for NP_001028515.1

Status: PROVISIONAL

Source sequence(s)

AC151478, AK158017, BB626493

Consensus CDS

CCDS37997.1

UniProtKB/Swiss-Prot

Q3TZ89, Q811L4

Related

ENSMUSP00000064900.8, ENSMUST00000063632.14

Conserved Domains (4) summary

COG2319
Location:31 → 326

WD40; WD40 repeat [General function prediction only]

sd00039
Location:63 → 115

7WD40; WD40 repeat [structural motif]

cl02567
Location:13 → 328

WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

cl14807
Location:544 → 765

ACE1-Sec16-like; Ancestral coatomer element 1 (ACE1) of COPII coat complex assembly protein Sec16