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    nup188 nucleoporin 188 [ Danio rerio (zebrafish) ]

    Gene ID: 559225, updated on 2-Nov-2024

    Summary

    Official Symbol
    nup188provided by ZNC
    Official Full Name
    nucleoporin 188provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-030131-7184
    See related
    Ensembl:ENSDARG00000030022 AllianceGenome:ZFIN:ZDB-GENE-030131-7184
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    fk95d02; wu:fk95d02
    Summary
    Predicted to be a structural constituent of nuclear pore. Predicted to be involved in RNA export from nucleus and protein import into nucleus. Predicted to act upstream of or within mRNA transport and protein transport. Predicted to be located in nucleus. Predicted to be part of nuclear pore inner ring. Human ortholog(s) of this gene implicated in Sandestig-Stefanova syndrome and respiratory failure. Orthologous to human NUP188 (nucleoporin 188). [provided by Alliance of Genome Resources, Nov 2024]
    Orthologs
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    Genomic context

    See nup188 in Genome Data Viewer
    Location:
    chromosome: 21
    Exon count:
    44
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 21 NC_007132.7 (4540114..4606642)
    105 previous assembly GRCz10 (GCF_000002035.5) 21 NC_007132.6 (4375495..4442077)

    Chromosome 21 - NC_007132.7Genomic Context describing neighboring genes Neighboring gene phytanoyl-CoA dioxygenase domain containing 1 Neighboring gene dolichol kinase Neighboring gene CDK5 regulatory subunit associated protein 2 Neighboring gene si:dkey-102g19.3

    Genomic regions, transcripts, and products

    Expression

    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    General gene information

    Markers

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables structural constituent of nuclear pore IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables structural constituent of nuclear pore IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    involved_in RNA export from nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    acts_upstream_of_or_within mRNA transport IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in protein import into nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    acts_upstream_of_or_within protein transport IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    part_of nuclear pore IEA
    Inferred from Electronic Annotation
    more info
     
    part_of nuclear pore inner ring IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    nucleoporin NUP188 homolog; nucleoporin NUP188

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007132.7 Reference GRCz11 Primary Assembly

      Range
      4540114..4606642
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_001922983.6XP_001923018.1  nucleoporin NUP188

      UniProtKB/TrEMBL
      A0A8M1QLP7, E7EXJ6
      Related
      ENSDARP00000043430.6, ENSDART00000043431.8
      Conserved Domains (1) summary
      pfam10487
      Location:29942
      Nup188; Nucleoporin subcomplex protein binding to Pom34