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    ftr83 finTRIM family, member 83 [ Danio rerio (zebrafish) ]

    Gene ID: 565972, updated on 2-Nov-2024

    Summary

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    Official Symbol
    ftr83provided by ZNC
    Official Full Name
    finTRIM family, member 83provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-031002-11
    See related
    Ensembl:ENSDARG00000025403 AllianceGenome:ZFIN:ZDB-GENE-031002-11
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    sb:cb790; sb:cb833; wu:fc29h06; wu:fe16f04; si:dkey-7b17.2
    Summary
    Predicted to enable zinc ion binding activity. Predicted to be located in cytoplasm. Is expressed in several structures, including EVL; digestive system; ectoderm; hatching gland; and pleuroperitoneal region. Orthologous to human TRIM29 (tripartite motif containing 29). [provided by Alliance of Genome Resources, Nov 2024]
    Orthologs
    all
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    Genomic context

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    See ftr83 in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 5 NC_007116.7 (30741725..30749494)
    105 previous assembly GRCz10 (GCF_000002035.5) 5 NC_007116.6 (30141572..30149341)

    Chromosome 5 - NC_007116.7Genomic Context describing neighboring genes Neighboring gene finTRIM family, member 82 Neighboring gene uncharacterized LOC103908733 Neighboring gene uncharacterized protein C22orf31-like Neighboring gene RuvB-like AAA ATPase 2

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. FTR67, a member of the fish-specific finTRIM family, triggers IFN pathway and against spring viremia of carp virus. Huo S, et al. Fish Shellfish Immunol, 2020 Aug. PMID 32334126
    2. Analysis of the expression patterns of the novel large multigene TRIM gene family (finTRIM) in zebrafish. Luo K, et al. Fish Shellfish Immunol, 2017 Jul. PMID 28461211
    3. Bioinformatics and expression analysis of finTRIM genes in grass carp, Ctenopharyngodon idella. Luo K, et al. Fish Shellfish Immunol, 2017 Jul. PMID 28476675
    4. FTR33, a member of fish-specific TRIM (finTRIM) subfamily, regulates negatively type I IFN antiviral immunity in zebrafish. Huang L, et al. Dev Comp Immunol, 2023 May. PMID 36801427
    5. FTR83, a Member of the Large Fish-Specific finTRIM Family, Triggers IFN Pathway and Counters Viral Infection. Langevin C, et al. Front Immunol, 2017. PMID 28603526, Free PMC Article

    See all (11) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    finTRIM family, member 83

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001326487.1 → NP_001313416.1  finTRIM family, member 83 isoform 1

      Status: VALIDATED

      Source sequence(s)
      BC114304, BC134873, BX276103
      UniProtKB/TrEMBL
      A0A8M1P3D9, A4IG09
      Related
      ENSDARP00000155163.1, ENSDART00000186992.1
      Conserved Domains (4) summary
      cd00162
      Location:8 → 51
      RING; RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in ...
      pfam00643
      Location:145 → 183
      zf-B_box; B-box zinc finger
      pfam02970
      Location:173 → 261
      TBCA; Tubulin binding cofactor A
      cd16040
      Location:396 → 574
      SPRY_PRY_SNTX; Stonustoxin subunit alpha or SNTX subunit alpha

    2. NM_001326488.1 → NP_001313417.1  finTRIM family, member 83 isoform 2

      Status: VALIDATED

      Source sequence(s)
      BC114304, BX276103
      UniProtKB/TrEMBL
      A0A8M1P2R5, B0S5N0, Q29RA4
      Related
      ENSDARP00000147950.1, ENSDART00000182533.1
      Conserved Domains (3) summary
      cd00162
      Location:8 → 51
      RING; RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in ...
      pfam00643
      Location:145 → 183
      zf-B_box; B-box zinc finger
      cl23899
      Location:174 → 316
      Spore_YpjB; Sporulation protein YpjB (SpoYpjB)

    3. NM_001326489.1 → NP_001313418.1  finTRIM family, member 83 isoform 2

      Status: VALIDATED

      Source sequence(s)
      BC114304, BC134873, BX276103, CF416994
      UniProtKB/TrEMBL
      A0A8M1P2R5, B0S5N0, Q29RA4
      Related
      ENSDARP00000089018.4, ENSDART00000098246.5
      Conserved Domains (3) summary
      cd00162
      Location:8 → 51
      RING; RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in ...
      pfam00643
      Location:145 → 183
      zf-B_box; B-box zinc finger
      cl23899
      Location:174 → 316
      Spore_YpjB; Sporulation protein YpjB (SpoYpjB)

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007116.7 Reference GRCz11 Primary Assembly

      Range
      30741725..30749494
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Reference GRCz11 ALT_DRER_TU_1

    Genomic

    1. NW_018394583.1 Reference GRCz11 ALT_DRER_TU_1

      Range
      23750..31519
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein
    Heading Accession and Version

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