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    ube2q1 ubiquitin-conjugating enzyme E2Q family member 1 [ Danio rerio (zebrafish) ]

    Gene ID: 553603, updated on 9-Dec-2024

    Summary

    Official Symbol
    ube2q1provided by ZNC
    Official Full Name
    ubiquitin-conjugating enzyme E2Q family member 1provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-050522-329
    See related
    Ensembl:ENSDARG00000100766 AllianceGenome:ZFIN:ZDB-GENE-050522-329
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    wu:fi42b06; zgc:110254
    Summary
    Predicted to enable ubiquitin conjugating enzyme activity. Predicted to be involved in protein polyubiquitination. Predicted to be active in nucleus. Orthologous to several human genes including UBE2Q2 (ubiquitin conjugating enzyme E2 Q2). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
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    Genomic context

    See ube2q1 in Genome Data Viewer
    Location:
    chromosome: 18
    Exon count:
    14
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 18 NC_007129.7 (50600989..50676658, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 18 NC_007129.6 (50604424..50618180, complement)

    Chromosome 18 - NC_007129.7Genomic Context describing neighboring genes Neighboring gene CD276 molecule Neighboring gene uncharacterized LOC101884348 Neighboring gene uncharacterized LOC137488347 Neighboring gene ubiquitin-like 7b (bone marrow stromal cell-derived) Neighboring gene cholinergic receptor, nicotinic, beta 4 (neuronal) Neighboring gene cholinergic receptor, nicotinic, alpha 3 Neighboring gene galectin 4 Neighboring gene purinergic receptor P2Y1 Neighboring gene RAP2B, member of RAS oncogene family

    Genomic regions, transcripts, and products

    Expression

    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    General protein information

    Preferred Names
    ubiquitin-conjugating enzyme E2 Q1
    Names
    ubiquitin-conjugating enzyme E2Q (putative) 1
    NP_001295534.1
    XP_005173748.1
    XP_068070871.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001308605.1NP_001295534.1  ubiquitin-conjugating enzyme E2 Q1

      See identical proteins and their annotated locations for NP_001295534.1

      Status: VALIDATED

      Source sequence(s)
      CU640433
      UniProtKB/TrEMBL
      A0A8M1P6J3, A0A8M9PFF6, A8KBW2
      Related
      ENSDARP00000134948.1, ENSDART00000159481.3
      Conserved Domains (1) summary
      cl00154
      Location:203359
      UBCc; Ubiquitin-conjugating enzyme E2, catalytic (UBCc) domain. This is part of the ubiquitin-mediated protein degradation pathway in which a thiol-ester linkage forms between a conserved cysteine and the C-terminus of ubiquitin and complexes with ubiquitin ...

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007129.7 Reference GRCz11 Primary Assembly

      Range
      50600989..50676658 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_068214770.1XP_068070871.1  ubiquitin-conjugating enzyme E2 Q1 isoform X2

    2. XM_005173691.5XP_005173748.1  ubiquitin-conjugating enzyme E2 Q1 isoform X1

      UniProtKB/TrEMBL
      A0A0R4IYY2, A0A8M2BKZ3, A0A8M9PA27
      Related
      ENSDARP00000141380.1, ENSDART00000171207.3
      Conserved Domains (1) summary
      cl00154
      Location:208364
      UBCc; Ubiquitin-conjugating enzyme E2, catalytic (UBCc) domain. This is part of the ubiquitin-mediated protein degradation pathway in which a thiol-ester linkage forms between a conserved cysteine and the C-terminus of ubiquitin and complexes with ubiquitin ...

    Suppressed Reference Sequence(s)

    The following Reference Sequences have been suppressed. Explain

    1. NM_001020579.1: Suppressed sequence

      Description
      NM_001020579.1: This RefSeq was removed because it is a nonsense-mediated mRNA decay (NMD) candidate.