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    pclaf PCNA clamp associated factor [ Danio rerio (zebrafish) ]

    Gene ID: 100333229, updated on 14-Nov-2024

    Summary

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    Official Symbol
    pclafprovided by ZNC
    Official Full Name
    PCNA clamp associated factorprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-131127-543
    See related
    AllianceGenome:ZFIN:ZDB-GENE-131127-543
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    kiaa0101; si:zfos-332c3.1
    Summary
    Predicted to enable chromatin binding activity. Predicted to be involved in translesion synthesis. Predicted to act upstream of or within DNA repair and regulation of cell cycle. Predicted to be located in membrane and perinuclear region of cytoplasm. Predicted to be active in nucleus. Orthologous to human PCLAF (PCNA clamp associated factor). [provided by Alliance of Genome Resources, Nov 2024]
    Orthologs
    human mouse all
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    Genomic context

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    See pclaf in Genome Data Viewer
    Location:
    chromosome: 25
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 25 NC_007136.7 (123185..188855)
    105 previous assembly GRCz10 (GCF_000002035.5) 25 NC_007136.6 (176127..179091)

    Chromosome 25 - NC_007136.7Genomic Context describing neighboring genes Neighboring gene contactin 1a Neighboring gene uncharacterized LOC110438374 Neighboring gene uncharacterized LOC108181599 Neighboring gene hepatic triacylglycerol lipase Neighboring gene disintegrin and metalloproteinase domain-containing protein 10-like Neighboring gene neuronal cell adhesion molecule b Neighboring gene ADAM metallopeptidase domain 10b Neighboring gene von Willebrand factor A domain-containing protein 5A-like Neighboring gene aquaporin 9a Neighboring gene small nucleolar RNA SNORA71 Neighboring gene small nucleolar RNA SNORA71 Neighboring gene zgc:114188

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. A 3D Atlas of Hematopoietic Stem and Progenitor Cell Expansion by Multi-dimensional RNA-Seq Analysis. Xue Y, et al. Cell Rep, 2019 Apr 30. PMID 31042481
    2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article
    3. Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database. Pasquier J, et al. BMC Genomics, 2016 May 18. PMID 27189481, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by ZFIN

    Process Evidence Code Pubs
    acts_upstream_of_or_within DNA damage response IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within DNA repair IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within regulation of cell cycle IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in perinuclear region of cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    PCNA-associated factor

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007136.7 Reference GRCz11 Primary Assembly

      Range
      123185..188855
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_002666755.6 → XP_002666801.3  PCNA-associated factor

    RNA

    1. XR_011008704.1 RNA Sequence

    Nucleotide Protein Strain
    Heading Accession and Version

    Gene LinkOut

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