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    chst14 carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 14 [ Danio rerio (zebrafish) ]

    Gene ID: 404732, updated on 14-Nov-2024

    Summary

    Official Symbol
    chst14provided by ZNC
    Official Full Name
    carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 14provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-040401-3
    See related
    Ensembl:ENSDARG00000043011 AllianceGenome:ZFIN:ZDB-GENE-040401-3
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    d4st1; wu:fc04a01; zgc:136487
    Summary
    Predicted to enable N-acetylgalactosamine 4-O-sulfotransferase activity. Predicted to be involved in dermatan sulfate proteoglycan metabolic process. Predicted to act upstream of or within carbohydrate biosynthetic process. Predicted to be located in Golgi membrane. Is expressed in head; midbrain hindbrain boundary; notochord; pectoral fin; and spinal cord. Human ortholog(s) of this gene implicated in Ehlers-Danlos syndrome musculocontractural type 1. Orthologous to human CHST14 (carbohydrate sulfotransferase 14). [provided by Alliance of Genome Resources, Nov 2024]
    Orthologs
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    Genomic context

    See chst14 in Genome Data Viewer
    Location:
    chromosome: 20
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 20 NC_007131.7 (25739979..25748311, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 20 NC_007131.6 (25840889..25849221, complement)

    Chromosome 20 - NC_007131.7Genomic Context describing neighboring genes Neighboring gene capping protein inhibiting regulator of actin dynamics Neighboring gene centrosomal protein 135 Neighboring gene transfer RNA cysteine (anticodon GCA) Neighboring gene transfer RNA cysteine (anticodon GCA)

    Genomic regions, transcripts, and products

    Expression

    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Pathways from PubChem

    General gene information

    Markers

    Clone Names

    • MGC136487

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables dermatan 4-sulfotransferase ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    enables sulfotransferase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables sulfotransferase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables transferase activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    acts_upstream_of_or_within carbohydrate biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in dermatan sulfate proteoglycan metabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in dermatan sulfate proteoglycan metabolic process ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    Component Evidence Code Pubs
    located_in Golgi apparatus IEA
    Inferred from Electronic Annotation
    more info
     
    located_in Golgi membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    carbohydrate sulfotransferase 14
    Names
    D4ST-1
    dermatan 4-sulfotransferase 1
    zD4ST-1
    NP_997994.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_212829.1NP_997994.1  carbohydrate sulfotransferase 14

      See identical proteins and their annotated locations for NP_997994.1

      Status: PROVISIONAL

      Source sequence(s)
      AB089140
      UniProtKB/Swiss-Prot
      Q805E5
      UniProtKB/TrEMBL
      Q1RM39
      Related
      ENSDARP00000063151.4, ENSDART00000063152.5
      Conserved Domains (1) summary
      pfam03567
      Location:133355
      Sulfotransfer_2; Sulfotransferase family

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007131.7 Reference GRCz11 Primary Assembly

      Range
      25739979..25748311 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)