eml2 EMAP like 2 [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: eml2provided by ZNC
Official Full Name: EMAP like 2provided by ZNC
Primary source: ZFIN:ZDB-GENE-050706-71
See related: Ensembl:ENSDARG00000008808 AllianceGenome:ZFIN:ZDB-GENE-050706-71
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: wu:fq15f04; zgc:110445
Summary: Predicted to enable microtubule binding activity. Predicted to be involved in microtubule cytoskeleton organization. Predicted to colocalize with mitotic spindle. Is expressed in several structures, including Kupffer's vesicle; forerunner cell group; hatching gland; lens placode; and nervous system. Orthologous to human EML2 (EMAP like 2). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: all
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Genomic context

Location:: chromosome: 15

Exon count:: 23

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	15	NC_007126.7 (28881125..28907707, complement)
105	previous assembly	GRCz10 (GCF_000002035.5)	15	NC_007126.6 (28948252..28974831, complement)

Chromosome 15 - NC_007126.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables microtubule binding	IBA Inferred from Biological aspect of Ancestor more info

Process	Evidence Code	Pubs
involved_in microtubule cytoskeleton organization	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
colocalizes_with mitotic spindle	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: echinoderm microtubule-associated protein-like 2

Names: echinoderm microtubule associated protein like 2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001030235.1 → NP_001025406.1 echinoderm microtubule-associated protein-like 2

See identical proteins and their annotated locations for NP_001025406.1

Status: PROVISIONAL

Source sequence(s)

BC098557

UniProtKB/TrEMBL

A0A8M3AHE0, Q4KMH7

Related

ENSDARP00000008223.8, ENSDART00000017268.10

Conserved Domains (4) summary

COG2319
Location:232 → 697

WD40; WD40 repeat [General function prediction only]

pfam03451
Location:175 → 248

HELP; HELP motif

sd00039
Location:367 → 404

7WD40; WD40 repeat [structural motif]

cl02567
Location:449 → 802

WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

NC_007126.7 Reference GRCz11 Primary Assembly

Range

28881125..28907707 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_005157653.5 → XP_005157710.1 echinoderm microtubule-associated protein-like 2 isoform X1

UniProtKB/TrEMBL

A0A8M2B400, A0A8M3AHE0

Conserved Domains (4) summary

COG2319
Location:75 → 540

WD40; WD40 repeat [General function prediction only]

pfam03451
Location:18 → 91

HELP; HELP motif

sd00039
Location:210 → 247

7WD40; WD40 repeat [structural motif]

cl02567
Location:292 → 645

WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...