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    errfi1a ERBB receptor feedback inhibitor 1a [ Danio rerio (zebrafish) ]

    Gene ID: 798009, updated on 2-Nov-2024

    Summary

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    Official Symbol
    errfi1aprovided by ZNC
    Official Full Name
    ERBB receptor feedback inhibitor 1aprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-030131-6256
    See related
    Ensembl:ENSDARG00000104039 AllianceGenome:ZFIN:ZDB-GENE-030131-6256
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    errfi1; wu:fd60d02; wu:fi40f02; zgc:162129
    Summary
    Predicted to be involved in negative regulation of epidermal growth factor receptor signaling pathway and regulation of keratinocyte differentiation. Orthologous to human ERRFI1 (ERBB receptor feedback inhibitor 1). [provided by Alliance of Genome Resources, Nov 2024]
    Orthologs
    human mouse all
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    Genomic context

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    See errfi1a in Genome Data Viewer
    Location:
    chromosome: 11
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 11 NC_007122.7 (40831633..40844026)
    105 previous assembly GRCz10 (GCF_000002035.5) 11 NC_007122.6 (40567488..40579881)

    Chromosome 11 - NC_007122.7Genomic Context describing neighboring genes Neighboring gene taste receptor, type 1, member 3 Neighboring gene uncharacterized LOC137496731 Neighboring gene uncharacterized LOC101882681 Neighboring gene uncharacterized LOC110440109 Neighboring gene uncharacterized LOC137496732

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. DNA Methylation of T1R1 Gene in the Vegetarian Adaptation of Grass Carp Ctenopharyngodon idella. Cai W, et al. Sci Rep, 2018 May 2. PMID 29720695, Free PMC Article
    2. Transcriptome analysis of Traf6 function in the innate immune response of zebrafish embryos. Stockhammer OW, et al. Mol Immunol, 2010 Nov-Dec. PMID 20851470
    3. Transcriptomic, proteomic, and metabolomic landscape of positional memory in the caudal fin of zebrafish. Rabinowitz JS, et al. Proc Natl Acad Sci U S A, 2017 Jan 31. PMID 28096348, Free PMC Article
    4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    5. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    See all (6) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    Markers

    Homology

    Clone Names

    • MGC162129

    Gene Ontology Provided by ZFIN

    Process Evidence Code Pubs
    involved_in negative regulation of epidermal growth factor receptor signaling pathway IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in regulation of keratinocyte differentiation IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    ERBB receptor feedback inhibitor 1a
    Names
    ERBB receptor feedback inhibitor 1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001083570.1 → NP_001077039.1  ERBB receptor feedback inhibitor 1a

      See identical proteins and their annotated locations for NP_001077039.1

      Status: PROVISIONAL

      Source sequence(s)
      BC133880
      UniProtKB/TrEMBL
      A0A8M1NDU2, A3KNJ9
      Related
      ENSDARP00000130213.1, ENSDART00000160023.3
      Conserved Domains (2) summary
      pfam09027
      Location:12 → 73
      GTPase_binding; GTPase binding
      pfam11555
      Location:324 → 368
      Inhibitor_Mig-6; EGFR receptor inhibitor Mig-6

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007122.7 Reference GRCz11 Primary Assembly

      Range
      40831633..40844026
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein
    Heading Accession and Version

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