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    pik3ip1 phosphoinositide-3-kinase interacting protein 1 [ Danio rerio (zebrafish) ]

    Gene ID: 386643, updated on 2-Nov-2024

    Summary

    Official Symbol
    pik3ip1provided by ZNC
    Official Full Name
    phosphoinositide-3-kinase interacting protein 1provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-031030-14
    See related
    Ensembl:ENSDARG00000003281 AllianceGenome:ZFIN:ZDB-GENE-031030-14
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    zgc:66482
    Summary
    Predicted to enable endopeptidase activity and signaling receptor binding activity. Predicted to be involved in negative regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction. Predicted to be located in plasma membrane. Predicted to be active in extracellular space. Is expressed in several structures, including immature eye; nervous system; optic primordium; pancreatic system; and yolk syncytial layer. Orthologous to human PIK3IP1 (phosphoinositide-3-kinase interacting protein 1). [provided by Alliance of Genome Resources, Nov 2024]
    Orthologs
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    Genomic context

    See pik3ip1 in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 5 NC_007116.7 (20866572..20879565, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 5 NC_007116.6 (20362772..20375704, complement)

    Chromosome 5 - NC_007116.7Genomic Context describing neighboring genes Neighboring gene si:ch211-225b11.1 Neighboring gene LIM domain kinase 2 Neighboring gene si:ch211-225b11.4 Neighboring gene si:dkey-174n20.1

    Genomic regions, transcripts, and products

    Expression

    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    General gene information

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables endopeptidase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables signaling receptor binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Process Evidence Code Pubs
    involved_in negative regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    is_active_in extracellular space IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    phosphoinositide-3-kinase-interacting protein 1
    Names
    HGFL
    kringle domain-containing protein HGFL

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_198374.2NP_938188.2  phosphoinositide-3-kinase-interacting protein 1 precursor

      Status: VALIDATED

      Source sequence(s)
      BX927203
      Related
      ENSDARP00000115818.1, ENSDART00000134697.2

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007116.7 Reference GRCz11 Primary Assembly

      Range
      20866572..20879565 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)