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    ano10b anoctamin 10b [ Danio rerio (zebrafish) ]

    Gene ID: 565195, updated on 14-Nov-2024

    Summary

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    Official Symbol
    ano10bprovided by ZNC
    Official Full Name
    anoctamin 10bprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-061013-169
    See related
    Ensembl:ENSDARG00000018159 AllianceGenome:ZFIN:ZDB-GENE-061013-169
    Gene type
    protein coding
    RefSeq status
    PREDICTED
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    zgc:153923
    Summary
    Predicted to enable chloride channel activity. Predicted to be involved in chloride transmembrane transport. Predicted to be located in membrane. Predicted to be active in plasma membrane. Human ortholog(s) of this gene implicated in autosomal recessive spinocerebellar ataxia 10. Orthologous to human ANO10 (anoctamin 10). [provided by Alliance of Genome Resources, Nov 2024]
    Orthologs
    all
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    Genomic context

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    See ano10b in Genome Data Viewer
    Location:
    chromosome: 25
    Exon count:
    16
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 25 NC_007136.7 (13528257..13558262, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 25 NC_007136.6 (13431857..13461814, complement)

    Chromosome 25 - NC_007136.7Genomic Context describing neighboring genes Neighboring gene lactate dehydrogenase D Neighboring gene SNF related kinase b Neighboring gene fatty acid 2-hydroxylase Neighboring gene casein kinase 2, alpha prime polypeptide b

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
    2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article
    4. Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database. Pasquier J, et al. BMC Genomics, 2016 May 18. PMID 27189481, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Clone Names

    • MGC153923

    Gene Ontology Provided by ZFIN

    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein LOC565195

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001077382.1 → NP_001070850.1  uncharacterized protein LOC565195

      See identical proteins and their annotated locations for NP_001070850.1

      Status: PREDICTED

      Source sequence(s)
      BC124774
      UniProtKB/TrEMBL
      Q08BD4
      Related
      ENSDARP00000094607.2, ENSDART00000103831.4
      Conserved Domains (1) summary
      pfam04547
      Location:215 → 663
      Anoctamin; Calcium-activated chloride channel

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007136.7 Reference GRCz11 Primary Assembly

      Range
      13528257..13558262 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_021470507.2 → XP_021326182.1  uncharacterized protein LOC565195 isoform X1

      UniProtKB/TrEMBL
      A0A8M9P6G3
      Conserved Domains (1) summary
      pfam04547
      Location:331 → 777
      Anoctamin; Calcium-activated chloride channel

    2. XM_021470508.2 → XP_021326183.1  uncharacterized protein LOC565195 isoform X3

      UniProtKB/TrEMBL
      A0A8M9PGV6
      Conserved Domains (1) summary
      pfam04547
      Location:215 → 661
      Anoctamin; Calcium-activated chloride channel

    3. XM_068217398.1 → XP_068073499.1  uncharacterized protein LOC565195 isoform X2

    Nucleotide Protein
    Heading Accession and Version

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