anxa5b annexin A5b [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: anxa5bprovided by ZNC
Official Full Name: annexin A5bprovided by ZNC
Primary source: ZFIN:ZDB-GENE-030131-9076
See related: Ensembl:ENSDARG00000016470 AllianceGenome:ZFIN:ZDB-GENE-030131-9076
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: anx; anx5; ANX V; anxa5; cb989; wu:fa98f06; wu:fj10f10
Summary: Predicted to enable calcium-dependent phospholipid binding activity and phosphatidylserine binding activity. Acts upstream of or within regulation of cell motility. Located in cytoplasm. Is expressed in atrioventricular canal; olfactory system; swim bladder; swim bladder bud; and visceral peritoneum. Human ortholog(s) of this gene implicated in autoimmune disease of the nervous system; myocardial infarction; and systemic scleroderma. Orthologous to human ANXA5 (annexin A5). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs: all
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Genomic context

Location:: chromosome: 1

Exon count:: 13

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	1	NC_007112.7 (22654884..22665092)
105	previous assembly	GRCz10 (GCF_000002035.5)	1	NC_007112.6 (21964145..21974353)

Chromosome 1 - NC_007112.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

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General gene information

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Markers

anx (e-PCR)
- UniSTS:205682

fa98f06.x1 (e-PCR)
- UniSTS:202627

AW203168 (e-PCR)
- UniSTS:205714

fb07f04.x1 (e-PCR)
- UniSTS:202738

Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables calcium ion binding	IEA Inferred from Electronic Annotation more info
enables calcium-dependent phospholipid binding	IBA Inferred from Biological aspect of Ancestor more info
enables calcium-dependent phospholipid binding	IEA Inferred from Electronic Annotation more info
enables phosphatidylserine binding	IBA Inferred from Biological aspect of Ancestor more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within negative regulation of coagulation	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within regulation of cell motility	IGI Inferred from Genetic Interaction more info	PubMed

Component	Evidence Code	Pubs
is_active_in cytoplasm	IBA Inferred from Biological aspect of Ancestor more info
located_in cytoplasm	IDA Inferred from Direct Assay more info	PubMed
is_active_in nucleus	IBA Inferred from Biological aspect of Ancestor more info
is_active_in plasma membrane	IBA Inferred from Biological aspect of Ancestor more info
is_active_in vesicle membrane	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: annexin A5b

Names: annexin 5; annexin A5

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.