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    zbtb14 zinc finger and BTB domain containing 14 [ Danio rerio (zebrafish) ]

    Gene ID: 406857, updated on 14-Nov-2024

    Summary

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    Official Symbol
    zbtb14provided by ZNC
    Official Full Name
    zinc finger and BTB domain containing 14provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-040426-2946
    See related
    Ensembl:ENSDARG00000098273 AllianceGenome:ZFIN:ZDB-GENE-040426-2946
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    zfp161; zgc:66442; wu:fd56f03
    Summary
    Predicted to enable DNA-binding transcription repressor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Predicted to be active in nucleoplasm. Orthologous to human ZBTB14 (zinc finger and BTB domain containing 14). [provided by Alliance of Genome Resources, Nov 2024]
    Orthologs
    human mouse all
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    Genomic context

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    See zbtb14 in Genome Data Viewer
    Location:
    chromosome: 24
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 24 NC_007135.7 (41988850..41995790)
    105 previous assembly GRCz10 (GCF_000002035.5) 24 NC_007135.6 (42048194..42054066, complement)

    Chromosome 24 - NC_007135.7Genomic Context describing neighboring genes Neighboring gene transmembrane protein 200C, genome duplicate a Neighboring gene erythrocyte membrane protein band 4.1-like 3a Neighboring gene DNA topoisomerase I mitochondrial Neighboring gene protein APCDD1-like

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables DNA-binding transcription repressor activity, RNA polymerase II-specific IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in negative regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in regulation of cytokine production IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in regulation of immune system process IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in nucleoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    zinc finger and BTB domain-containing protein 14
    Names
    zinc finger protein 161 homolog

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_213536.1 → NP_998701.1  zinc finger and BTB domain-containing protein 14

      See identical proteins and their annotated locations for NP_998701.1

      Status: PROVISIONAL

      Source sequence(s)
      BC054705
      UniProtKB/TrEMBL
      A0A8M2BLJ1, Q7SYJ3
      Related
      ENSDARP00000141581.1, ENSDART00000169725.2
      Conserved Domains (6) summary
      smart00225
      Location:31 → 122
      BTB; Broad-Complex, Tramtrack and Bric a brac
      COG5048
      Location:273 → 408
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:301 → 321
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:299 → 321
      zf-C2H2; Zinc finger, C2H2 type
      pfam00651
      Location:20 → 123
      BTB; BTB/POZ domain
      pfam13465
      Location:313 → 338
      zf-H2C2_2; Zinc-finger double domain

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007135.7 Reference GRCz11 Primary Assembly

      Range
      41988850..41995790
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_005174204.5 → XP_005174261.1  zinc finger and BTB domain-containing protein 14 isoform X1

      See identical proteins and their annotated locations for XP_005174261.1

      UniProtKB/TrEMBL
      A0A8M2BLJ1, Q7SYJ3
      Conserved Domains (6) summary
      smart00225
      Location:31 → 122
      BTB; Broad-Complex, Tramtrack and Bric a brac
      COG5048
      Location:273 → 408
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:301 → 321
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:299 → 321
      zf-C2H2; Zinc finger, C2H2 type
      pfam00651
      Location:20 → 123
      BTB; BTB/POZ domain
      pfam13465
      Location:313 → 338
      zf-H2C2_2; Zinc-finger double domain

    2. XM_009297676.4 → XP_009295951.1  zinc finger and BTB domain-containing protein 14 isoform X1

      See identical proteins and their annotated locations for XP_009295951.1

      UniProtKB/TrEMBL
      A0A8M2BLJ1, Q7SYJ3
      Conserved Domains (6) summary
      smart00225
      Location:31 → 122
      BTB; Broad-Complex, Tramtrack and Bric a brac
      COG5048
      Location:273 → 408
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:301 → 321
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:299 → 321
      zf-C2H2; Zinc finger, C2H2 type
      pfam00651
      Location:20 → 123
      BTB; BTB/POZ domain
      pfam13465
      Location:313 → 338
      zf-H2C2_2; Zinc-finger double domain
    Nucleotide Protein Strain
    Heading Accession and Version

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