mettl25 methyltransferase like 25 [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: mettl25provided by ZNC
Official Full Name: methyltransferase like 25provided by ZNC
Primary source: ZFIN:ZDB-GENE-041210-90
See related: Ensembl:ENSDARG00000045754 AllianceGenome:ZFIN:ZDB-GENE-041210-90
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: zgc:136889; si:dkey-21h14.1
Summary: Predicted to enable methyltransferase activity. Predicted to act upstream of or within methylation. Orthologous to human METTL25 (methyltransferase like 25). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 4

Exon count:: 13

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	4	NC_007115.7 (11030708..11053543, complement)
105	previous assembly	GRCz10 (GCF_000002035.5)	4	NC_007115.6 (11036788..11054674, complement)

Chromosome 4 - NC_007115.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables methyltransferase activity	IEA Inferred from Electronic Annotation more info
enables transferase activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within methylation	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: probable methyltransferase-like protein 25

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001045057.1 → NP_001038522.1 probable methyltransferase-like protein 25

Status: PROVISIONAL

Source sequence(s)

BX784029

UniProtKB/TrEMBL

A0A8M1N9Y4, Q5RGQ0

Related

ENSDARP00000067261.5, ENSDART00000067262.6

Conserved Domains (1) summary

cl17173
Location:142 → 405

AdoMet_MTases; S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy). ...