nudcd2 NudC domain containing 2 [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: nudcd2provided by ZNC
Official Full Name: NudC domain containing 2provided by ZNC
Primary source: ZFIN:ZDB-GENE-040801-49
See related: Ensembl:ENSDARG00000078059 AllianceGenome:ZFIN:ZDB-GENE-040801-49
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: zgc:100842
Summary: Predicted to enable unfolded protein binding activity. Acts upstream of or within cilium assembly and determination of left/right symmetry. Predicted to be active in cytoplasm. Orthologous to human NUDCD2 (NudC domain containing 2). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 14

Exon count:: 4

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	14	NC_007125.7 (22140258..22152013, complement)
105	previous assembly	GRCz10 (GCF_000002035.5)	14	NC_007125.6 (21843013..21854768, complement)

Chromosome 14 - NC_007125.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Markers

fk49e06.x1 (e-PCR)
- UniSTS:201075

fb07e04.x1 (e-PCR)
- UniSTS:202734

Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables unfolded protein binding	IBA Inferred from Biological aspect of Ancestor more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within cilium assembly	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within cilium organization	IGI Inferred from Genetic Interaction more info	PubMed
acts_upstream_of_or_within determination of left/right symmetry	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in protein folding	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
is_active_in cytoplasm	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: nudC domain-containing protein 2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001003539.1 → NP_001003539.1 nudC domain-containing protein 2

See identical proteins and their annotated locations for NP_001003539.1

Status: PROVISIONAL

Source sequence(s)

BC078187

UniProtKB/TrEMBL

A0A8M1N1J1, Q6DC89

Related

ENSDARP00000102198.2, ENSDART00000115422.3

Conserved Domains (1) summary

cd06494
Location:12 → 104

p23_NUDCD2_like; p23-like NUD (nuclear distribution) C-like found in human NUDC domain-containing protein 2 (NUDCD2) and similar proteins. Little is known about the function of the proteins in this subgroup.