napepld N-acyl phosphatidylethanolamine phospholipase D [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: napepldprovided by ZNC
Official Full Name: N-acyl phosphatidylethanolamine phospholipase Dprovided by ZNC
Primary source: ZFIN:ZDB-GENE-030131-3856
See related: Ensembl:ENSDARG00000009252 AllianceGenome:ZFIN:ZDB-GENE-030131-3856
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: fc56b11; nape-pld; wu:fc56b11; zgc:158854; si:dkey-65m5.3
Summary: Predicted to enable N-acylphosphatidylethanolamine-specific phospholipase D activity. Predicted to be involved in N-acylethanolamine metabolic process and N-acylphosphatidylethanolamine metabolic process. Predicted to act upstream of or within phospholipid catabolic process. Predicted to be located in Golgi membrane and early endosome membrane. Predicted to be active in cytoplasm. Orthologous to human NAPEPLD (N-acyl phosphatidylethanolamine phospholipase D). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: human mouse all
NEW: Try the new Gene table
Try the new Transcript table

Genomic context

Location:: chromosome: 4

Exon count:: 5

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	4	NC_007115.7 (20480399..20485508, complement)
105	previous assembly	GRCz10 (GCF_000002035.5)	4	NC_007115.6 (20759419..20765007, complement)

Chromosome 4 - NC_007115.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to reference sequence details

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

Go to the top of the page Help

See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

Go to the top of the page Help

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Submit: New GeneRIF Correction

General gene information

Go to the top of the page Help

Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables N-acylphosphatidylethanolamine-specific phospholipase D activity	IBA Inferred from Biological aspect of Ancestor more info
enables N-acylphosphatidylethanolamine-specific phospholipase D activity	IEA Inferred from Electronic Annotation more info
enables metal ion binding	IEA Inferred from Electronic Annotation more info
enables zinc ion binding	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in N-acylethanolamine metabolic process	IBA Inferred from Biological aspect of Ancestor more info
involved_in N-acylphosphatidylethanolamine metabolic process	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within lipid catabolic process	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within lipid metabolic process	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within phospholipid catabolic process	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in Golgi membrane	IEA Inferred from Electronic Annotation more info
is_active_in cytoplasm	IBA Inferred from Biological aspect of Ancestor more info
located_in early endosome membrane	IEA Inferred from Electronic Annotation more info
is_active_in membrane-bounded organelle	IBA Inferred from Biological aspect of Ancestor more info

General protein information

Go to the top of the page Help

Preferred Names: N-acyl-phosphatidylethanolamine-hydrolyzing phospholipase D

NP_001074082.2

EC 3.1.4.54

XP_005164954.2

EC 3.1.4.54

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001080613.2 → NP_001074082.2 N-acyl-phosphatidylethanolamine-hydrolyzing phospholipase D

See identical proteins and their annotated locations for NP_001074082.2

Status: VALIDATED

Source sequence(s)

BX248410, CD014813, EB868982

UniProtKB/TrEMBL

A0A2R8RJ40, A0A8M1NCU2, A0A8M2BC81

Related

ENSDARP00000154110.1, ENSDART00000183276.1

Conserved Domains (2) summary

COG2220
Location:97 → 353

UlaG; L-ascorbate metabolism protein UlaG, beta-lactamase superfamily [Carbohydrate transport and metabolism]

cl23716
Location:98 → 283

metallo-hydrolase-like_MBL-fold; mainly hydrolytic enzymes and related proteins which carry out various biological functions; MBL-fold metallohydrolase domain