riox1 ribosomal oxygenase 1 [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: riox1provided by ZNC
Official Full Name: ribosomal oxygenase 1provided by ZNC
Primary source: ZFIN:ZDB-GENE-041008-221
See related: Ensembl:ENSDARG00000067838 AllianceGenome:ZFIN:ZDB-GENE-041008-221
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: no66; no66a; im:7141580; zgc:162967
Summary: Predicted to enable 2-oxoglutarate-dependent dioxygenase activity and iron ion binding activity. Predicted to be involved in negative regulation of DNA-templated transcription and negative regulation of osteoblast differentiation. Predicted to act upstream of or within chromatin organization. Predicted to be located in nucleus. Predicted to be active in nucleolus. Orthologous to human RIOX1 (ribosomal oxygenase 1). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 20

Exon count:: 15

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	20	NC_007131.7 (50015689..50044757)
105	previous assembly	GRCz10 (GCF_000002035.5)	20	NC_007131.6 (50212485..50242523)

Chromosome 20 - NC_007131.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

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General gene information

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Markers

fe14c07.y1 (e-PCR)
- UniSTS:196188

fb97h02.x1 (e-PCR)
- UniSTS:191952

Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables 2-oxoglutarate-dependent dioxygenase activity	ISS Inferred from Sequence or Structural Similarity more info
enables dioxygenase activity	IEA Inferred from Electronic Annotation more info
enables histone H3K36 demethylase activity	IBA Inferred from Biological aspect of Ancestor more info
enables histone H3K36 demethylase activity	ISS Inferred from Sequence or Structural Similarity more info
enables histone H3K36me/H3K36me2 demethylase activity	IEA Inferred from Electronic Annotation more info
enables histone H3K4 demethylase activity	IBA Inferred from Biological aspect of Ancestor more info
enables histone H3K4me/H3K4me2/H3K4me3 demethylase activity	ISS Inferred from Sequence or Structural Similarity more info
enables iron ion binding	ISS Inferred from Sequence or Structural Similarity more info
enables metal ion binding	IEA Inferred from Electronic Annotation more info
enables oxidoreductase activity	IEA Inferred from Electronic Annotation more info
enables peptidyl-histidine dioxygenase activity	IEA Inferred from Electronic Annotation more info
enables peptidyl-histidine dioxygenase activity	ISS Inferred from Sequence or Structural Similarity more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within chromatin organization	IEA Inferred from Electronic Annotation more info
involved_in negative regulation of DNA-templated transcription	ISS Inferred from Sequence or Structural Similarity more info
involved_in negative regulation of osteoblast differentiation	ISS Inferred from Sequence or Structural Similarity more info

Component	Evidence Code	Pubs
is_active_in nucleolus	IBA Inferred from Biological aspect of Ancestor more info
located_in nucleoplasm	IEA Inferred from Electronic Annotation more info
located_in nucleus	IEA Inferred from Electronic Annotation more info
located_in nucleus	ISS Inferred from Sequence or Structural Similarity more info

General protein information

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Preferred Names: ribosomal oxygenase 1

Names: bifunctional lysine-specific demethylase and histidyl-hydroxylase NO66; histone lysine demethylase NO66; lysine-specific demethylase NO66; nucleolar protein 66

NP_001082857.1

EC 1.14.11.27

EC 1.14.11.79

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.