lipt1 lipoyltransferase 1 [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: lipt1provided by ZNC
Official Full Name: lipoyltransferase 1provided by ZNC
Primary source: ZFIN:ZDB-GENE-060929-112
See related: Ensembl:ENSDARG00000025233 AllianceGenome:ZFIN:ZDB-GENE-060929-112
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: fi89f05; wu:fi89f05; zgc:152851
Summary: Predicted to enable lipoyltransferase activity. Predicted to act upstream of or within protein lipoylation. Predicted to be active in mitochondrion. Orthologous to human LIPT1 (lipoyltransferase 1). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 1

Exon count:: 1

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	1	NC_007112.7 (45922699..45924004)
105	previous assembly	GRCz10 (GCF_000002035.5)	1	NC_007112.6 (45230904..45232209)

Chromosome 1 - NC_007112.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables lipoyl(octanoyl) transferase activity	IEA Inferred from Electronic Annotation more info
enables lipoyltransferase activity	IBA Inferred from Biological aspect of Ancestor more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within protein lipoylation	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within protein modification process	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
is_active_in cytoplasm	IBA Inferred from Biological aspect of Ancestor more info
is_active_in mitochondrion	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: lipoyl amidotransferase LIPT1, mitochondrial

NP_001068570.1

EC 2.3.1.181

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001075102.2 → NP_001068570.1 lipoyl amidotransferase LIPT1, mitochondrial

See identical proteins and their annotated locations for NP_001068570.1

Status: PROVISIONAL

Source sequence(s)

BC124156

UniProtKB/TrEMBL

Q08CP2

Related

ENSDARP00000031386.6, ENSDART00000033669.8

Conserved Domains (2) summary

TIGR00545
Location:33 → 335

lipoyltrans; lipoyltransferase and lipoate-protein ligase

COG0095
Location:44 → 278

LplA; Lipoate-protein ligase A [Coenzyme transport and metabolism]