maf1a MAF1 homolog, negative regulator of RNA polymerase III a [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: maf1aprovided by ZNC
Official Full Name: MAF1 homolog, negative regulator of RNA polymerase III aprovided by ZNC
Primary source: ZFIN:ZDB-GENE-040426-2788
See related: Ensembl:ENSDARG00000013122 AllianceGenome:ZFIN:ZDB-GENE-040426-2788
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: maf1; zgc:63803; wu:fb92h08; wu:fd61g02
Summary: Predicted to enable RNA polymerase III core binding activity. Predicted to be involved in negative regulation of transcription by RNA polymerase III. Predicted to be located in cytoplasm. Predicted to be active in nucleus. Is expressed in female organism and male organism. Orthologous to human MAF1 (MAF1 homolog, negative regulator of RNA polymerase III). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs: all
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Genomic context

Location:: chromosome: 11

Exon count:: 7

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	11	NC_007122.7 (24046179..24056609)
105	previous assembly	GRCz10 (GCF_000002035.5)	11	NC_007122.6 (23808322..23818752)

Chromosome 11 - NC_007122.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Multiple approaches support a central role for PP4 in Maf1 dephosphorylation.
Title: PP4 dephosphorylates Maf1 to couple multiple stress conditions to RNA polymerase III repression.

Submit: New GeneRIF Correction

General gene information

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Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables RNA polymerase III core binding	IBA Inferred from Biological aspect of Ancestor more info

Process	Evidence Code	Pubs
involved_in negative regulation of transcription by RNA polymerase III	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within negative regulation of transcription by RNA polymerase III	IEA Inferred from Electronic Annotation more info
involved_in negative regulation of transcription by RNA polymerase III	ISS Inferred from Sequence or Structural Similarity more info

Component	Evidence Code	Pubs
located_in cytoplasm	IEA Inferred from Electronic Annotation more info
located_in cytoplasm	ISS Inferred from Sequence or Structural Similarity more info
is_active_in nucleus	IBA Inferred from Biological aspect of Ancestor more info
located_in nucleus	IEA Inferred from Electronic Annotation more info
located_in nucleus	ISS Inferred from Sequence or Structural Similarity more info

General protein information

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Preferred Names: repressor of RNA polymerase III transcription MAF1 homolog

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.