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    atpsckmt fATP synthase c subunit lysine N-methyltransferase [ Danio rerio (zebrafish) ]

    Gene ID: 492519, updated on 2-Nov-2024

    Summary

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    Official Symbol
    atpsckmtprovided by ZNC
    Official Full Name
    fATP synthase c subunit lysine N-methyltransferaseprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-041114-90
    See related
    Ensembl:ENSDARG00000033451 AllianceGenome:ZFIN:ZDB-GENE-041114-90
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    fam173b; zgc:103579
    Summary
    Predicted to enable protein-lysine N-methyltransferase activity. Predicted to be involved in positive regulation of sensory perception of pain and regulation of mitochondrial ATP synthesis coupled proton transport. Predicted to act upstream of or within methylation. Predicted to be located in mitochondrial membrane. Predicted to be active in mitochondrion. Orthologous to human ATPSCKMT (ATP synthase c subunit lysine N-methyltransferase). [provided by Alliance of Genome Resources, Nov 2024]
    Orthologs
    all
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    Genomic context

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    See atpsckmt in Genome Data Viewer
    Location:
    chromosome: 2
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 2 NC_007113.7 (30480862..30483364)
    105 previous assembly GRCz10 (GCF_000002035.5) 2 NC_007113.6 (30497329..30500055)

    Chromosome 2 - NC_007113.7Genomic Context describing neighboring genes Neighboring gene neuropilin and tolloid-like protein 1 Neighboring gene cerebellin 2a precursor Neighboring gene uncharacterized LOC137487883 Neighboring gene membrane-associated ring finger (C3HC4) 6

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables methyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein-lysine N-methyltransferase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables protein-lysine N-methyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables transferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within methylation IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in positive regulation of sensory perception of pain IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in regulation of mitochondrial ATP synthesis coupled proton transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in mitochondrial membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in mitochondrion IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein LOC492519
    Names
    family with sequence similarity 173, member B

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001007391.2 → NP_001007392.2  uncharacterized protein LOC492519 isoform 2

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) uses an alternate splice site in the 3' coding region that results in a frameshift compared to variant 1. The resulting protein (isoform 2) is shorter and has a distinct C-terminus compared to isoform 1.
      Source sequence(s)
      CR388419, EH455280, EH549744, EH559135
      UniProtKB/TrEMBL
      A0A8M1N3B7, F1QDF7
      Related
      ENSDARP00000041377.4, ENSDART00000041378.6
      Conserved Domains (1) summary
      pfam12847
      Location:82 → 112
      Methyltransf_18; Methyltransferase domain

    2. NM_001291706.1 → NP_001278635.1  uncharacterized protein LOC492519 isoform 1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longer transcript and encodes the longer protein (isoform 1).
      Source sequence(s)
      CR388419, EH455280, EH559135
      UniProtKB/TrEMBL
      A0A8M1P0Q0, E7EXV0
      Related
      ENSDARP00000111927.2, ENSDART00000125933.3
      Conserved Domains (1) summary
      pfam12847
      Location:82 → 162
      Methyltransf_18; Methyltransferase domain

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007113.7 Reference GRCz11 Primary Assembly

      Range
      30480862..30483364
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version

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