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These reference sequences exist independently of genome builds. Explain
These reference sequences are curated independently of the genome
annotation cycle, so their versions may not match the RefSeq versions in the current
genome build. Identify version mismatches by comparing the version of the RefSeq in
this section to the one reported in Genomic regions,
transcripts, and products above.
Genomic
-
NG_046949.1 RefSeqGene
- Range
-
4773..94002
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
mRNA and Protein(s)
-
NM_007039.4 → NP_008970.2 tyrosine-protein phosphatase non-receptor type 21
See identical proteins and their annotated locations for NP_008970.2
Status: REVIEWED
- Source sequence(s)
-
AL049834, AL162171, BM930068, DA860560, X79510
- Consensus CDS
-
CCDS9884.1
- UniProtKB/Swiss-Prot
-
Q16825
- UniProtKB/TrEMBL
-
Q8WX29
- Related
- ENSP00000452414.1, ENST00000556564.6
- Conserved Domains (6) summary
-
- smart00194
Location:896 → 1166
- PTPc; Protein tyrosine phosphatase, catalytic domain
- smart00295
Location:24 → 222
- B41; Band 4.1 homologues
- cd00047
Location:923 → 1166
- PTPc; Protein tyrosine phosphatases (PTP) catalyze the dephosphorylation of phosphotyrosine peptides; they regulate phosphotyrosine levels in signal transduction pathways. The depth of the active site cleft renders the enzyme specific for phosphorylated Tyr ...
- cd13188
Location:217 → 307
- FERM_C_PTPN14_PTPN21; FERM domain C-lobe of Protein tyrosine phosphatase non-receptor proteins 14 and 21 (PTPN14 and 21)
- pfam00373
Location:109 → 220
- FERM_M; FERM central domain
- pfam09379
Location:27 → 90
- FERM_N; FERM N-terminal domain
The following sections contain reference sequences that belong to a
specific genome build. Explain
This section includes genomic Reference
Sequences (RefSeqs) from all assemblies on which this gene is annotated, such as
RefSeqs for chromosomes and scaffolds (contigs) from both reference and alternate
assemblies. Model RNAs and proteins are also reported here.
Reference GRCh38.p14 Primary Assembly
Genomic
-
NC_000014.9 Reference GRCh38.p14 Primary Assembly
- Range
-
88465778..88555007 complement
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
mRNA and Protein(s)
-
XM_005267287.4 → XP_005267344.1 tyrosine-protein phosphatase non-receptor type 21 isoform X1
See identical proteins and their annotated locations for XP_005267344.1
- UniProtKB/Swiss-Prot
-
Q16825
- UniProtKB/TrEMBL
-
Q8WX29
- Related
- ENSP00000330276.3, ENST00000328736.7
- Conserved Domains (6) summary
-
- smart00194
Location:896 → 1166
- PTPc; Protein tyrosine phosphatase, catalytic domain
- smart00295
Location:24 → 222
- B41; Band 4.1 homologues
- cd00047
Location:923 → 1166
- PTPc; Protein tyrosine phosphatases (PTP) catalyze the dephosphorylation of phosphotyrosine peptides; they regulate phosphotyrosine levels in signal transduction pathways. The depth of the active site cleft renders the enzyme specific for phosphorylated Tyr ...
- cd13188
Location:217 → 307
- FERM_C_PTPN14_PTPN21; FERM domain C-lobe of Protein tyrosine phosphatase non-receptor proteins 14 and 21 (PTPN14 and 21)
- pfam00373
Location:109 → 220
- FERM_M; FERM central domain
- pfam09379
Location:27 → 90
- FERM_N; FERM N-terminal domain
-
XM_011536367.4 → XP_011534669.1 tyrosine-protein phosphatase non-receptor type 21 isoform X1
See identical proteins and their annotated locations for XP_011534669.1
- UniProtKB/Swiss-Prot
-
Q16825
- UniProtKB/TrEMBL
-
Q8WX29
- Conserved Domains (6) summary
-
- smart00194
Location:896 → 1166
- PTPc; Protein tyrosine phosphatase, catalytic domain
- smart00295
Location:24 → 222
- B41; Band 4.1 homologues
- cd00047
Location:923 → 1166
- PTPc; Protein tyrosine phosphatases (PTP) catalyze the dephosphorylation of phosphotyrosine peptides; they regulate phosphotyrosine levels in signal transduction pathways. The depth of the active site cleft renders the enzyme specific for phosphorylated Tyr ...
- cd13188
Location:217 → 307
- FERM_C_PTPN14_PTPN21; FERM domain C-lobe of Protein tyrosine phosphatase non-receptor proteins 14 and 21 (PTPN14 and 21)
- pfam00373
Location:109 → 220
- FERM_M; FERM central domain
- pfam09379
Location:27 → 90
- FERM_N; FERM N-terminal domain
-
XM_011536368.3 → XP_011534670.1 tyrosine-protein phosphatase non-receptor type 21 isoform X2
See identical proteins and their annotated locations for XP_011534670.1
- UniProtKB/TrEMBL
-
Q8WX29
- Conserved Domains (4) summary
-
- smart00194
Location:773 → 1043
- PTPc; Protein tyrosine phosphatase, catalytic domain
- cd00047
Location:800 → 1043
- PTPc; Protein tyrosine phosphatases (PTP) catalyze the dephosphorylation of phosphotyrosine peptides; they regulate phosphotyrosine levels in signal transduction pathways. The depth of the active site cleft renders the enzyme specific for phosphorylated Tyr ...
- cd13188
Location:94 → 184
- FERM_C_PTPN14_PTPN21; FERM domain C-lobe of Protein tyrosine phosphatase non-receptor proteins 14 and 21 (PTPN14 and 21)
- pfam00373
Location:27 → 97
- FERM_M; FERM central domain
-
XM_017020939.2 → XP_016876428.1 tyrosine-protein phosphatase non-receptor type 21 isoform X3
- UniProtKB/TrEMBL
-
Q8WX29
- Conserved Domains (3) summary
-
- smart00194
Location:692 → 962
- PTPc; Protein tyrosine phosphatase, catalytic domain
- cd00047
Location:719 → 962
- PTPc; Protein tyrosine phosphatases (PTP) catalyze the dephosphorylation of phosphotyrosine peptides; they regulate phosphotyrosine levels in signal transduction pathways. The depth of the active site cleft renders the enzyme specific for phosphorylated Tyr ...
- cd13188
Location:13 → 103
- FERM_C_PTPN14_PTPN21; FERM domain C-lobe of Protein tyrosine phosphatase non-receptor proteins 14 and 21 (PTPN14 and 21)
Alternate T2T-CHM13v2.0
Genomic
-
NC_060938.1 Alternate T2T-CHM13v2.0
- Range
-
82686590..82775829 complement
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
mRNA and Protein(s)
-
XM_054375286.1 → XP_054231261.1 tyrosine-protein phosphatase non-receptor type 21 isoform X1
- UniProtKB/Swiss-Prot
-
Q16825
- UniProtKB/TrEMBL
-
Q8WX29
-
XM_054375287.1 → XP_054231262.1 tyrosine-protein phosphatase non-receptor type 21 isoform X1
- UniProtKB/Swiss-Prot
-
Q16825
- UniProtKB/TrEMBL
-
Q8WX29
-
XM_054375288.1 → XP_054231263.1 tyrosine-protein phosphatase non-receptor type 21 isoform X2
- UniProtKB/TrEMBL
-
Q8WX29
-
XM_054375289.1 → XP_054231264.1 tyrosine-protein phosphatase non-receptor type 21 isoform X3
- UniProtKB/TrEMBL
-
Q8WX29