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These reference sequences exist independently of genome builds. Explain
These reference sequences are curated independently of the genome
annotation cycle, so their versions may not match the RefSeq versions in the current
genome build. Identify version mismatches by comparing the version of the RefSeq in
this section to the one reported in Genomic regions,
transcripts, and products above.
Genomic
-
NG_029052.1 RefSeqGene
- Range
-
4650..177630
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
mRNA and Protein(s)
-
NM_000870.7 → NP_000861.1 5-hydroxytryptamine receptor 4 isoform b
See identical proteins and their annotated locations for NP_000861.1
Status: REVIEWED
- Description
- Transcript Variant: This variant (b) encodes the longest isoform (b).
- Source sequence(s)
-
AC008627, AC091971, AJ131724, DR000612
- Consensus CDS
-
CCDS4291.1
- UniProtKB/Swiss-Prot
- C4WYH4, Q13639, Q546Q1, Q684M0, Q712M9, Q96KH9, Q96KI0, Q9H199, Q9NY73, Q9UBM6, Q9UBT4, Q9UE22, Q9UE23, Q9UQR6
- UniProtKB/TrEMBL
- A0A2D3FAF9, Q8IXH9
- Related
- ENSP00000367120.4, ENST00000377888.8
- Conserved Domains (1) summary
-
- cd15056
Location:20 → 323
- 7tmA_5-HT4; serotonin receptor subtype 4, member of the class A family of seven-transmembrane G protein-coupled receptors
-
NM_001040169.2 → NP_001035259.1 5-hydroxytryptamine receptor 4 isoform a
See identical proteins and their annotated locations for NP_001035259.1
Status: REVIEWED
- Description
- Transcript Variant: This variant (a) differs in the 5' UTR, 3' coding region and 3' UTR, compared to variant b. The resulting isoform (a) has a distinct C-terminus and is shorter than isoform b.
- Source sequence(s)
-
AC114939, AJ131724, AJ278979, Y08756
- Consensus CDS
-
CCDS34270.1
- UniProtKB/TrEMBL
-
E5RK45
- Related
- ENSP00000428320.1, ENST00000521530.6
- Conserved Domains (1) summary
-
- pfam00001
Location:36 → 312
- 7tm_1; 7 transmembrane receptor (rhodopsin family)
-
NM_001040172.2 → NP_001035262.2 5-hydroxytryptamine receptor 4 isoform d
See identical proteins and their annotated locations for NP_001035262.2
Status: REVIEWED
- Description
- Transcript Variant: This variant (d) differs in the 5' UTR and uses an alternate 3' terminal exon compared to variant b. The encoded isoform (d) has a distinct C-terminus and is shorter than isoform b.
- Source sequence(s)
-
AC091971, AJ131724, Y12507
- Consensus CDS
-
CCDS34273.2
- UniProtKB/TrEMBL
-
E5RK45
- Related
- ENSP00000435904.1, ENST00000517929.5
- Conserved Domains (1) summary
-
- pfam00001
Location:36 → 312
- 7tm_1; 7 transmembrane receptor (rhodopsin family)
-
NM_001040173.2 → NP_001035263.1 5-hydroxytryptamine receptor 4 isoform i
See identical proteins and their annotated locations for NP_001035263.1
Status: REVIEWED
- Description
- Transcript Variant: This variant (i) differs in the 5' UTR and includes an alternate in-frame exon, compared to variant b. This results in a longer protein (isoform i), compared to isoform b.
- Source sequence(s)
-
AC091971, AJ131724, AJ131726
- Consensus CDS
-
CCDS34272.1
- UniProtKB/TrEMBL
-
Q8IXH9
- Related
- ENSP00000353915.3, ENST00000360693.7
- Conserved Domains (1) summary
-
- pfam00001
Location:36 → 312
- 7tm_1; 7 transmembrane receptor (rhodopsin family)
-
NM_001286410.1 → NP_001273339.1 5-hydroxytryptamine receptor 4 isoform c
See identical proteins and their annotated locations for NP_001273339.1
Status: REVIEWED
- Description
- Transcript Variant: This variant (c) has a shorter 5' UTR and uses an alternate exon in the 3' UTR and coding region. The encoded isoform (c) is shorter and has a distinct C-terminus compared to isoform b.
- Source sequence(s)
-
AC008627, AM712912, Y12506
- Consensus CDS
-
CCDS75353.1
- UniProtKB/TrEMBL
-
E5RK45
- Related
- ENSP00000427913.1, ENST00000520514.5
- Conserved Domains (2) summary
-
- pfam00001
Location:36 → 312
- 7tm_1; 7 transmembrane receptor (rhodopsin family)
- cl21561
Location:26 → 215
- 7tm_4; Olfactory receptor
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NM_199453.3 → NP_955525.1 5-hydroxytryptamine receptor 4 isoform g
See identical proteins and their annotated locations for NP_955525.1
Status: REVIEWED
- Description
- Transcript Variant: This variant (g), also known as E or G1, differs in the 5' UTR, 3' coding region and 3' UTR, compared to variant 1. The resulting isoform (isoform g) has a distinct C-terminus and is shorter than isoform b.
- Source sequence(s)
-
AC114939, AJ011371, AJ131724, AJ278981, Y08756
- Consensus CDS
-
CCDS34271.1
- UniProtKB/TrEMBL
-
E5RK45
- Related
- ENSP00000430979.1, ENST00000521735.5
- Conserved Domains (1) summary
-
- pfam00001
Location:36 → 312
- 7tm_1; 7 transmembrane receptor (rhodopsin family)
RNA
-
NR_104445.2 RNA Sequence
Status: REVIEWED
- Description
- Transcript Variant: This variant (j) uses an alternate exon at the 3' end compared to variant b. This variant (j) is represented as non-coding because the use of the 5'-most expected translational start codon, as used in variant 1, renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).
- Source sequence(s)
-
AC008627, AC091971, AK308471
The following sections contain reference sequences that belong to a
specific genome build. Explain
This section includes genomic Reference
Sequences (RefSeqs) from all assemblies on which this gene is annotated, such as
RefSeqs for chromosomes and scaffolds (contigs) from both reference and alternate
assemblies. Model RNAs and proteins are also reported here.
Reference GRCh38.p14 Primary Assembly
Genomic
-
NC_000005.10 Reference GRCh38.p14 Primary Assembly
- Range
-
148451032..148654527 complement
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
Alternate T2T-CHM13v2.0
Genomic
-
NC_060929.1 Alternate T2T-CHM13v2.0
- Range
-
148985559..149189026 complement
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
The following Reference Sequences have been suppressed. Explain
These RefSeqs were suppressed for the
cited reason(s). Suppressed RefSeqs do not appear in BLAST databases, related
sequence links, or BLAST links (BLink), but may still be retrieved by clicking on
their accession.version below.
-
NM_001040174.1: Suppressed sequence
- Description
- NM_001040174.1: This RefSeq was permanently suppressed because currently there is insufficient support for the transcript and the protein.