PAXIP1-DT PAXIP1 divergent transcript [Homo sapiens (human)] - Gene

Summary

Official Symbol: PAXIP1-DTprovided by HGNC
Official Full Name: PAXIP1 divergent transcriptprovided by HGNC
Primary source: HGNC:HGNC:27328
See related: Ensembl:ENSG00000273344 AllianceGenome:HGNC:27328
Gene type: ncRNA
RefSeq status: VALIDATED
Organism: Homo sapiens
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as: PAXIP1-AS1
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Genomic context

Location:: 7q36.2

Exon count:: 1

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCh38.p14 (GCF_000001405.40)	7	NC_000007.14 (155003433..155005703)
RS_2024_08	current	T2T-CHM13v2.0 (GCF_009914755.1)	7	NC_060931.1 (156178707..156180978)
RS_2024_09	previous assembly	GRCh37.p13 (GCF_000001405.25)	7	NC_000007.13 (154795143..154797413)

Chromosome 7 - NC_000007.14 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

PAXIP1-AS1 is associated with immune infiltration and predicts poor prognosis in ovarian cancer.
Title: PAXIP1-AS1 is associated with immune infiltration and predicts poor prognosis in ovarian cancer.
The HOXD9-mediated PAXIP1-AS1 regulates gastric cancer progression through PABPC1/PAK1 modulation.
Title: The HOXD9-mediated PAXIP1-AS1 regulates gastric cancer progression through PABPC1/PAK1 modulation.
LncRNA PAXIP1-AS1 fosters the pathogenesis of pulmonary arterial hypertension via ETS1/WIPF1/RhoA axis.
Title: LncRNA PAXIP1-AS1 fosters the pathogenesis of pulmonary arterial hypertension via ETS1/WIPF1/RhoA axis.
LncRNA PAXIP1-AS1 was highly expressed in glioma and associated with poor prognosis. Highly expressed lncRNA PAXIP1-AS1 promoted glioma cell migration, invasion and angiogenesis by recruiting transcription factor ETS1 to upregulate KIF14 expression. However, its silencing inhibited migration, invasion and angiogenesis of glioma cells.
Title: Long non-coding RNA PAXIP1-AS1 facilitates cell invasion and angiogenesis of glioma by recruiting transcription factor ETS1 to upregulate KIF14 expression.

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Phenotypes

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Review eQTL and phenotype association data in this region using PheGenI

Variation

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See variants in ClinVar

See studies and variants in dbVar

See Variation Viewer (GRCh37.p13)

See Variation Viewer (GRCh38)

General gene information

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Markers

RH104026 (e-PCR)
- UniSTS:98351

D8S2279 (e-PCR)
- UniSTS:473907

D10S16 (e-PCR)
- UniSTS:155756

RH48948 (e-PCR)
- UniSTS:55220

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.