cpt2 carnitine palmitoyltransferase 2 [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: cpt2provided by ZNC
Official Full Name: carnitine palmitoyltransferase 2provided by ZNC
Primary source: ZFIN:ZDB-GENE-030131-6719
See related: Ensembl:ENSDARG00000038618 AllianceGenome:ZFIN:ZDB-GENE-030131-6719
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: wu:fa03e08; wu:fb54a02; zgc:101627
Summary: Predicted to enable carnitine O-palmitoyltransferase activity. Predicted to be involved in fatty acid beta-oxidation. Predicted to act upstream of or within fatty acid metabolic process. Predicted to be located in mitochondrial inner membrane. Predicted to be active in mitochondrion. Is expressed in cardiac ventricle; intestine; and liver. Human ortholog(s) of this gene implicated in brain disease; lipid metabolism disorder; and muscular disease. Orthologous to human CPT2 (carnitine palmitoyltransferase 2). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 8

Exon count:: 6

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	8	NC_007119.7 (21137453..21142599, complement)
105	previous assembly	GRCz10 (GCF_000002035.5)	8	NC_007119.6 (21105370..21110514, complement)

Chromosome 8 - NC_007119.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Markers

fb54a02.x1 (e-PCR)
- UniSTS:203318

AA497292 (e-PCR)
- UniSTS:206935

Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables acyltransferase activity	IEA Inferred from Electronic Annotation more info
enables carnitine O-octanoyltransferase activity	IEA Inferred from Electronic Annotation more info
enables carnitine O-palmitoyltransferase activity	IBA Inferred from Biological aspect of Ancestor more info
enables carnitine O-palmitoyltransferase activity	IEA Inferred from Electronic Annotation more info
enables transferase activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in fatty acid beta-oxidation	IBA Inferred from Biological aspect of Ancestor more info
involved_in fatty acid beta-oxidation	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within fatty acid metabolic process	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within lipid metabolic process	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in membrane	IEA Inferred from Electronic Annotation more info
located_in mitochondrial inner membrane	IEA Inferred from Electronic Annotation more info
is_active_in mitochondrion	IBA Inferred from Biological aspect of Ancestor more info
located_in mitochondrion	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: carnitine O-palmitoyltransferase 2, mitochondrial

Names: CPT II; carnitine palmitoyltransferase II

NP_001007448.2

EC 2.3.1.21

XP_068078938.1

EC 2.3.1.21

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001007447.2 → NP_001007448.2 carnitine O-palmitoyltransferase 2, mitochondrial

Status: VALIDATED

Source sequence(s)

BX927144

UniProtKB/Swiss-Prot

B0S7W9, Q5U3U3

UniProtKB/TrEMBL

B2GQ15

Related

ENSDARP00000122226.1, ENSDART00000135938.3

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

NC_007119.7 Reference GRCz11 Primary Assembly

Range

21137453..21142599 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_068222837.1 → XP_068078938.1 carnitine O-palmitoyltransferase 2, mitochondrial isoform X1

UniProtKB/Swiss-Prot

B0S7W9, Q5U3U3

UniProtKB/TrEMBL

B2GQ15