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    baz1a bromodomain adjacent to zinc finger domain, 1A [ Danio rerio (zebrafish) ]

    Gene ID: 334173, updated on 9-Dec-2024

    Summary

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    Official Symbol
    baz1aprovided by ZNC
    Official Full Name
    bromodomain adjacent to zinc finger domain, 1Aprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-030131-6105
    See related
    Ensembl:ENSDARG00000099745 AllianceGenome:ZFIN:ZDB-GENE-030131-6105
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    fi34e04; im:6907928; wu:fi34e04
    Summary
    Predicted to enable DNA binding activity. Predicted to be involved in positive regulation of DNA replication; regulation of DNA-templated transcription; and regulation of heterochromatin formation. Predicted to act upstream of or within chromatin remodeling. Predicted to be located in nucleus. Predicted to be part of CHRAC. Predicted to be active in nuclear chromosome. Orthologous to human BAZ1A (bromodomain adjacent to zinc finger domain 1A). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    human mouse all
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    Genomic context

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    See baz1a in Genome Data Viewer
    Location:
    chromosome: 17
    Exon count:
    28
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 17 NC_007128.7 (10031791..10060007, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 17 NC_007128.6 (9875751..9903970, complement)

    Chromosome 17 - NC_007128.7Genomic Context describing neighboring genes Neighboring gene sorting nexin 6 Neighboring gene cofilin 2 (muscle) Neighboring gene zgc:109986 Neighboring gene signal recognition particle 54

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. A network of epigenetic regulators guides developmental haematopoiesis in vivo. Huang HT, et al. Nat Cell Biol, 2013 Dec. PMID 24240475, Free PMC Article
    2. Contrasted innate responses to two viruses in zebrafish: insights into the ancestral repertoire of vertebrate IFN-stimulated genes. Briolat V, et al. J Immunol, 2014 May 1. PMID 24683187
    3. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
    4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    5. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    acts_upstream_of_or_within chromatin remodeling IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    bromodomain adjacent to zinc finger domain protein 1A

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001365143.1 → NP_001352072.1  bromodomain adjacent to zinc finger domain protein 1A isoform 1

      Status: VALIDATED

      Source sequence(s)
      BX088587, CABZ01005612, CABZ01042488, CU928207
      UniProtKB/TrEMBL
      A0A8N7TEI0
      Conserved Domains (7) summary
      smart00571
      Location:406 → 467
      DDT; domain in different transcription and chromosome remodeling factors
      cd15627
      Location:1118 → 1163
      PHD_BAZ1A; PHD finger found in bromodomain adjacent to zinc finger domain protein 1A (BAZ1A)
      pfam10537
      Location:23 → 122
      WAC_Acf1_DNA_bd; ATP-utilising chromatin assembly and remodelling N-terminal
      pfam15612
      Location:570 → 615
      WHIM1; WSTF, HB1, Itc1p, MBD9 motif 1
      pfam15613
      Location:759 → 875
      WSD; Williams-Beuren syndrome DDT (WSD), D-TOX E motif
      cl02556
      Location:1353 → 1457
      Bromodomain; Bromodomain. Bromodomains are found in many chromatin-associated proteins and in nuclear histone acetyltransferases. They interact specifically with acetylated lysine.
      cl26511
      Location:618 → 747
      Neuromodulin_N; Gap junction protein N-terminal region

    2. NM_001365144.1 → NP_001352073.1  bromodomain adjacent to zinc finger domain protein 1A isoform 2

      Status: VALIDATED

      Source sequence(s)
      BX088587, CABZ01005612, CABZ01042488, CU928207
      UniProtKB/TrEMBL
      A0A8M6YTY8
      Related
      ENSDARP00000086641.5, ENSDART00000092209.6
      Conserved Domains (7) summary
      smart00571
      Location:406 → 467
      DDT; domain in different transcription and chromosome remodeling factors
      cd15627
      Location:1118 → 1163
      PHD_BAZ1A; PHD finger found in bromodomain adjacent to zinc finger domain protein 1A (BAZ1A)
      pfam10537
      Location:23 → 122
      WAC_Acf1_DNA_bd; ATP-utilising chromatin assembly and remodelling N-terminal
      pfam15612
      Location:570 → 615
      WHIM1; WSTF, HB1, Itc1p, MBD9 motif 1
      pfam15613
      Location:759 → 875
      WSD; Williams-Beuren syndrome DDT (WSD), D-TOX E motif
      cl02556
      Location:1352 → 1456
      Bromodomain; Bromodomain. Bromodomains are found in many chromatin-associated proteins and in nuclear histone acetyltransferases. They interact specifically with acetylated lysine.
      cl26511
      Location:618 → 747
      Neuromodulin_N; Gap junction protein N-terminal region

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007128.7 Reference GRCz11 Primary Assembly

      Range
      10031791..10060007 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version

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