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    snip1 Smad nuclear interacting protein [ Danio rerio (zebrafish) ]

    Gene ID: 793873, updated on 2-Nov-2024

    Summary

    Official Symbol
    snip1provided by ZNC
    Official Full Name
    Smad nuclear interacting proteinprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-041026-3
    See related
    Ensembl:ENSDARG00000087528 AllianceGenome:ZFIN:ZDB-GENE-041026-3
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Summary
    Predicted to enable mRNA binding activity. Acts upstream of or within mRNA splicing, via spliceosome. Predicted to be active in nucleus. Is expressed in several structures, including blastodisc; fourth ventricle; notochord; otic vesicle; and pectoral fin bud. Orthologous to human SNIP1 (Smad nuclear interacting protein 1). [provided by Alliance of Genome Resources, Nov 2024]
    Orthologs
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    Genomic context

    See snip1 in Genome Data Viewer
    Location:
    chromosome: 16
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 16 NC_007127.7 (33930864..33937924)
    105 previous assembly GRCz10 (GCF_000002035.5) 16 NC_007127.6 (33976834..33983894)

    Chromosome 16 - NC_007127.7Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC137487930 Neighboring gene G protein nucleolar 2 Neighboring gene dynein, axonemal, light intermediate chain 1 Neighboring gene GPN-loop GTPase 2 Neighboring gene AT-rich interaction domain 1Aa

    Genomic regions, transcripts, and products

    Expression

    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Pathways from PubChem

    General gene information

    Markers

    Clone Names

    • MGC114106

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables mRNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Process Evidence Code Pubs
    acts_upstream_of_or_within mRNA splicing, via spliceosome IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in miRNA processing IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    General protein information

    Preferred Names
    smad nuclear-interacting protein 1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001025470.1NP_001020641.1  smad nuclear-interacting protein 1

      See identical proteins and their annotated locations for NP_001020641.1

      Status: PROVISIONAL

      Source sequence(s)
      BC097166
      UniProtKB/TrEMBL
      A0A8M1N734, Q4V8W8
      Related
      ENSDARP00000108908.3, ENSDART00000125945.5
      Conserved Domains (2) summary
      COG1716
      Location:253344
      FHA; Forkhead associated (FHA) domain, binds pSer, pThr, pTyr [Signal transduction mechanisms]
      cd00060
      Location:236339
      FHA; Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins ...

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007127.7 Reference GRCz11 Primary Assembly

      Range
      33930864..33937924
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)