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    stk38a serine/threonine kinase 38a [ Danio rerio (zebrafish) ]

    Gene ID: 406765, updated on 9-Dec-2024

    Summary

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    Official Symbol
    stk38aprovided by ZNC
    Official Full Name
    serine/threonine kinase 38aprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-040426-2811
    See related
    Ensembl:ENSDARG00000019973 AllianceGenome:ZFIN:ZDB-GENE-040426-2811
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    zgc:55572; wu:fj80h03
    Summary
    Predicted to enable protein serine/threonine kinase activity. Predicted to be involved in intracellular signal transduction. Predicted to act upstream of or within protein phosphorylation. Orthologous to human STK38 (serine/threonine kinase 38). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See stk38a in Genome Data Viewer
    Location:
    chromosome: 8
    Exon count:
    14
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 8 NC_007119.7 (25590850..25605531, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 8 NC_007119.6 (25567885..25586392, complement)

    Chromosome 8 - NC_007119.7Genomic Context describing neighboring genes Neighboring gene phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1 Neighboring gene uncharacterized LOC137496360 Neighboring gene transmembrane protein 81 Neighboring gene solute carrier family 38 member 5a Neighboring gene WASP actin nucleation promoting factor a

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. Proteome dynamics in neutrophils of adult zebrafish upon chemically-induced inflammation. Singh SK, et al. Fish Shellfish Immunol, 2014 Sep. PMID 25014315
    2. Eumetazoan cryptochrome phylogeny and evolution. Haug MF, et al. Genome Biol Evol, 2015 Jan 18. PMID 25601102, Free PMC Article
    3. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
    4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    5. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables nucleotide binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein serine/threonine kinase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables protein serine/threonine kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables transferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in intracellular signal transduction IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    acts_upstream_of_or_within phosphorylation IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within protein phosphorylation IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    serine/threonine-protein kinase 38
    NP_998621.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_213456.1 → NP_998621.1  serine/threonine-protein kinase 38

      See identical proteins and their annotated locations for NP_998621.1

      Status: PROVISIONAL

      Source sequence(s)
      BC044428
      UniProtKB/TrEMBL
      A0A8M1PH51, Q803L5
      Related
      ENSDARP00000003411.5, ENSDART00000005906.6
      Conserved Domains (2) summary
      smart00220
      Location:89 → 382
      S_TKc; Serine/Threonine protein kinases, catalytic domain
      cd05628
      Location:87 → 464
      STKc_NDR1; Catalytic domain of the Serine/Threonine Kinase, Nuclear Dbf2-Related kinase 1

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007119.7 Reference GRCz11 Primary Assembly

      Range
      25590850..25605531 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version

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