chmp2a charged multivesicular body protein 2A [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: chmp2aprovided by ZNC
Official Full Name: charged multivesicular body protein 2Aprovided by ZNC
Primary source: ZFIN:ZDB-GENE-040426-2922
See related: Ensembl:ENSDARG00000053979 AllianceGenome:ZFIN:ZDB-GENE-040426-2922
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: bc2; fj10d05; zgc:55361; wu:fi18h03; wu:fj10d05
Summary: Predicted to be involved in several processes, including endosome transport via multivesicular body sorting pathway; exit from mitosis; and late endosome to vacuole transport. Predicted to act upstream of or within vacuolar transport. Predicted to be located in nuclear envelope. Predicted to be part of ESCRT III complex. Predicted to be active in multivesicular body. Orthologous to human CHMP2A (charged multivesicular body protein 2A). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 12

Exon count:: 6

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	12	NC_007123.7 (27027314..27031031, complement)
105	previous assembly	GRCz10 (GCF_000002035.5)	12	NC_007123.6 (26935954..26939671, complement)

Chromosome 12 - NC_007123.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

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General gene information

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Gene Ontology Provided by ZFIN

Process	Evidence Code	Pubs
involved_in endosome transport via multivesicular body sorting pathway	IBA Inferred from Biological aspect of Ancestor more info
involved_in exit from mitosis	ISS Inferred from Sequence or Structural Similarity more info
involved_in late endosome to vacuole transport	IBA Inferred from Biological aspect of Ancestor more info
involved_in nuclear membrane reassembly	ISS Inferred from Sequence or Structural Similarity more info
involved_in protein transport	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within protein transport	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within vacuolar transport	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
part_of ESCRT III complex	IBA Inferred from Biological aspect of Ancestor more info
located_in cytoplasm	IEA Inferred from Electronic Annotation more info
located_in endosome	IEA Inferred from Electronic Annotation more info
located_in late endosome membrane	IEA Inferred from Electronic Annotation more info
located_in membrane	IEA Inferred from Electronic Annotation more info
is_active_in multivesicular body	IBA Inferred from Biological aspect of Ancestor more info
located_in nuclear envelope	ISS Inferred from Sequence or Structural Similarity more info

General protein information

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Preferred Names: charged multivesicular body protein 2a

Names: chromatin modifying protein 2A; chromatin-modifying protein 2a; putative breast adenocarcinoma marker

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.