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    pdia6 protein disulfide isomerase family A, member 6 [ Danio rerio (zebrafish) ]

    Gene ID: 322160, updated on 2-Nov-2024

    Summary

    Official Symbol
    pdia6provided by ZNC
    Official Full Name
    protein disulfide isomerase family A, member 6provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-030131-879
    See related
    Ensembl:ENSDARG00000009001 AllianceGenome:ZFIN:ZDB-GENE-030131-879
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    pdip5; pdi-p5; wu:fb51h08; wu:fc09e09
    Summary
    Predicted to enable protein-disulfide reductase activity. Predicted to be involved in response to endoplasmic reticulum stress. Predicted to be active in endoplasmic reticulum. Is expressed in several structures, including axis; hatching gland; nervous system; pectoral fin musculature; and polster. Orthologous to human PDIA6 (protein disulfide isomerase family A member 6). [provided by Alliance of Genome Resources, Nov 2024]
    Orthologs
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    Genomic context

    See pdia6 in Genome Data Viewer
    Location:
    chromosome: 20
    Exon count:
    13
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 20 NC_007131.7 (31217591..31231122)
    105 previous assembly GRCz10 (GCF_000002035.5) 20 NC_007131.6 (31314712..31328243)

    Chromosome 20 - NC_007131.7Genomic Context describing neighboring genes Neighboring gene ciliary microtubule inner protein 2C Neighboring gene otoferlin a Neighboring gene hippocalcin-like 1 Neighboring gene apolipoprotein Bb, tandem duplicate 1

    Genomic regions, transcripts, and products

    Expression

    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    General gene information

    Markers

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables isomerase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables protein disulfide isomerase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables protein-disulfide reductase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Process Evidence Code Pubs
    involved_in response to endoplasmic reticulum stress IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    is_active_in endoplasmic reticulum IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    General protein information

    Preferred Names
    protein disulfide-isomerase A6
    Names
    protein disulfide isomerase-related protein (provisional)
    NP_922915.2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_197933.2NP_922915.2  protein disulfide-isomerase A6 precursor

      See identical proteins and their annotated locations for NP_922915.2

      Status: PROVISIONAL

      Source sequence(s)
      BC044507
      UniProtKB/TrEMBL
      Q803F3
      Related
      ENSDARP00000027662.6, ENSDART00000020252.7
      Conserved Domains (3) summary
      cd02983
      Location:275404
      P5_C; P5 family, C-terminal redox inactive TRX-like domain; P5 is a protein disulfide isomerase (PDI)-related protein with a domain structure of aa'b (where a and a' are redox active TRX domains and b is a redox inactive TRX-like domain). Like PDI, P5 is ...
      cd03001
      Location:26128
      PDI_a_P5; PDIa family, P5 subfamily; composed of eukaryotic proteins similar to human P5, a PDI-related protein with a domain structure of aa'b (where a and a' are redox active TRX domains and b is a redox inactive TRX-like domain). Like PDI, P5 is located in the ...
      TIGR01130
      Location:25262
      ER_PDI_fam; protein disulfide isomerase, eukaryotic

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007131.7 Reference GRCz11 Primary Assembly

      Range
      31217591..31231122
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)