hexd hexosaminidase d [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: hexdprovided by ZNC
Official Full Name: hexosaminidase dprovided by ZNC
Primary source: ZFIN:ZDB-GENE-060929-448
See related: Ensembl:ENSDARG00000061216 AllianceGenome:ZFIN:ZDB-GENE-060929-448
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: hexdc; fj33c04; wu:fj33c04; zgc:152869
Summary: Predicted to enable hexosaminidase activity. Predicted to act upstream of or within carbohydrate metabolic process. Orthologous to human HEXD (hexosaminidase D). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs: all
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Genomic context

Location:: chromosome: 12

Exon count:: 12

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	12	NC_007123.7 (26611426..26620728, complement)
105	previous assembly	GRCz10 (GCF_000002035.5)	12	NC_007123.6 (26520066..26529368, complement)

Chromosome 12 - NC_007123.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables beta-N-acetylhexosaminidase activity	IEA Inferred from Electronic Annotation more info
enables hexosaminidase activity	IBA Inferred from Biological aspect of Ancestor more info
enables hexosaminidase activity	IEA Inferred from Electronic Annotation more info
enables hydrolase activity	IEA Inferred from Electronic Annotation more info
enables hydrolase activity, hydrolyzing O-glycosyl compounds	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within carbohydrate metabolic process	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: hexosaminidase D

Names: hexosaminidase (glycosyl hydrolase family 20, catalytic domain) containing

NP_001070635.2

EC 3.2.1.52

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001077167.2 → NP_001070635.2 hexosaminidase D

Status: VALIDATED

Source sequence(s)

BX470098

UniProtKB/TrEMBL

A0A8M1NBL6, F1R118

Related

ENSDARP00000081501.4, ENSDART00000087067.5

Conserved Domains (1) summary

cd06565
Location:9 → 326

GH20_GcnA-like; Glycosyl hydrolase family 20 (GH20) catalytic domain of N-acetyl-beta-D-glucosaminidase (GcnA, also known as BhsA) and related proteins. GcnA is an exoglucosidase which cleaves N-acetyl-beta-D-galactosamine (NAG) and N-acetyl-beta-D-galactosamine ...