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    tmem198ab transmembrane protein 198ab [ Danio rerio (zebrafish) ]

    Gene ID: 564608, updated on 2-Nov-2024

    Summary

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    Official Symbol
    tmem198abprovided by ZNC
    Official Full Name
    transmembrane protein 198abprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-050809-123
    See related
    Ensembl:ENSDARG00000034685 AllianceGenome:ZFIN:ZDB-GENE-050809-123
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    tmem198; tmem198b; zgc:112212
    Summary
    Predicted to be involved in positive regulation of canonical Wnt signaling pathway. Predicted to be located in membrane. Predicted to be active in cytoplasmic vesicle and plasma membrane. Is expressed in anterior macula. Orthologous to human TMEM198 (transmembrane protein 198). [provided by Alliance of Genome Resources, Nov 2024]
    Orthologs
    human mouse all
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    Genomic context

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    See tmem198ab in Genome Data Viewer
    Location:
    chromosome: 6
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 6 NC_007117.7 (13782089..13870158)
    105 previous assembly GRCz10 (GCF_000002035.5) 6 NC_007117.6 (13676969..13740721)

    Chromosome 6 - NC_007117.7Genomic Context describing neighboring genes Neighboring gene wingless-type MMTV integration site family, member 6a Neighboring gene cyclin dependent kinase 5, regulatory subunit 2a (p39) Neighboring gene crystallin, beta A2a Neighboring gene microRNA 375-1 Neighboring gene uncharacterized LOC137495835 Neighboring gene uncharacterized LOC110439862 Neighboring gene desmin b Neighboring gene aspartyl aminopeptidase

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. Analysis and functional evaluation of the hair-cell transcriptome. McDermott BM Jr, et al. Proc Natl Acad Sci U S A, 2007 Jul 10. PMID 17606911, Free PMC Article
    2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article
    4. Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database. Pasquier J, et al. BMC Genomics, 2016 May 18. PMID 27189481, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Clone Names

    • MGC112212

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in positive regulation of canonical Wnt signaling pathway IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cytoplasmic vesicle IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    transmembrane protein 198-B
    Names
    transmembrane protein 198
    transmembrane protein 198b

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001033919.2 → NP_001029091.1  transmembrane protein 198-B

      See identical proteins and their annotated locations for NP_001029091.1

      Status: VALIDATED

      Source sequence(s)
      CU652701, CU929360
      UniProtKB/Swiss-Prot
      Q498W5
      UniProtKB/TrEMBL
      A0A8M9QFG9
      Related
      ENSDARP00000043521.5, ENSDART00000043522.7
      Conserved Domains (1) summary
      pfam13886
      Location:48 → 239
      DUF4203; Domain of unknown function (DUF4203)

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007117.7 Reference GRCz11 Primary Assembly

      Range
      13782089..13870158
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_021476900.2 → XP_021332575.1  transmembrane protein 198-B isoform X1

      UniProtKB/Swiss-Prot
      Q498W5
      UniProtKB/TrEMBL
      A0A8M9QFG9
      Related
      ENSDARP00000155749.1, ENSDART00000182899.1
      Conserved Domains (1) summary
      pfam13886
      Location:48 → 239
      DUF4203; Domain of unknown function (DUF4203)

    2. XM_021476899.2 → XP_021332574.1  transmembrane protein 198-B isoform X1

      UniProtKB/Swiss-Prot
      Q498W5
      UniProtKB/TrEMBL
      A0A8M9QFG9
      Conserved Domains (1) summary
      pfam13886
      Location:48 → 239
      DUF4203; Domain of unknown function (DUF4203)

    3. XM_009302265.4 → XP_009300540.1  transmembrane protein 198-B isoform X1

      See identical proteins and their annotated locations for XP_009300540.1

      UniProtKB/Swiss-Prot
      Q498W5
      UniProtKB/TrEMBL
      A0A8M9QFG9
      Conserved Domains (1) summary
      pfam13886
      Location:48 → 239
      DUF4203; Domain of unknown function (DUF4203)

    4. XM_068221759.1 → XP_068077860.1  transmembrane protein 198-B isoform X1

    Reference GRCz11 ALT_DRER_TU_1

    Genomic

    1. NW_018394628.1 Reference GRCz11 ALT_DRER_TU_1

      Range
      4642..22664
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q498W5.1 GenPept UniProtKB/Swiss-Prot:Q498W5

    Gene LinkOut

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