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    MGA MAX dimerization protein MGA [ Homo sapiens (human) ]

    Gene ID: 23269, updated on 10-Dec-2024

    Summary

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    Official Symbol
    MGAprovided by HGNC
    Official Full Name
    MAX dimerization protein MGAprovided by HGNC
    Primary source
    HGNC:HGNC:14010
    See related
    Ensembl:ENSG00000174197 MIM:616061; AllianceGenome:HGNC:14010
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    MAD5; MXD5
    Summary
    Predicted to enable DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in cell fate specification and positive regulation of transcription by RNA polymerase II. Predicted to act upstream of or within cellular response to leukemia inhibitory factor. Part of MLL1 complex. [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Ubiquitous expression in ovary (RPKM 5.9), testis (RPKM 5.5) and 25 other tissues See more
    Orthologs
    mouse all
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    Genomic context

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    See MGA in Genome Data Viewer
    Location:
    15q15.1
    Exon count:
    28
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 15 NC_000015.10 (41621224..41769940)
    RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 15 NC_060939.1 (39427379..39575822)
    RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 15 NC_000015.9 (41913422..42062138)

    Chromosome 15 - NC_000015.10Genomic Context describing neighboring genes Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 6365 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr15:41851897-41852538 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr15:41854571-41855258 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr15:41856635-41857321 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr15:41860135-41860642 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr15:41860643-41861148 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr15:41861657-41862163 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 6366 Neighboring gene TYRO3 protein tyrosine kinase Neighboring gene H3K4me1 hESC enhancer GRCh37_chr15:41888161-41888662 Neighboring gene uncharacterized LOC105370791 Neighboring gene uncharacterized LOC124903614 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 6367 Neighboring gene microRNA 626 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 9285 Neighboring gene mitogen-activated protein kinase binding protein 1 Neighboring gene JMJD7-PLA2G4B readthrough Neighboring gene H3K4me1 hESC enhancer GRCh37_chr15:42117960-42118842 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 9286 Neighboring gene Sharpr-MPRA regulatory region 5929 Neighboring gene jumonji domain containing 7

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Tissue-specific circular RNA induction during human fetal development
    • Description: 35 human fetal samples from 6 tissues (3 - 7 replicates per tissue) collected between 10 and 20 weeks gestational time were sequenced using Illumina TruSeq Stranded Total RNA
    • BioProject: PRJNA270632
    • Publication: PMID 26076956
    • Analysis date: Mon Apr 2 22:54:59 2018

    Bibliography

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    Related articles in PubMed

    1. In vivo CRISPR screens identify Mga as an immunotherapy target in triple-negative breast cancer. Feng X, et al. Proc Natl Acad Sci U S A, 2024 Sep 24. PMID 39298484,
    2. Somatic mutation of a candidate tumour suppressor MGA gene and its mutational heterogeneity in colorectal cancers. Jo YS, et al. Pathology, 2016 Aug. PMID 27306572
    3. Generation of monoclonal antibodies against MGA and comparison of their application in breast cancer detection by immunohistochemistry. Duan C, et al. Sci Rep, 2015 Aug 14. PMID 26272389, Free PMC Article
    4. Functional characterization of cooperating MGA mutations in RUNX1::RUNX1T1 acute myeloid leukemia. Thomas ME 3rd, et al. Leukemia, 2024 May. PMID 38454121, Free PMC Article
    5. Multi-Omics Analysis Identifies MGA as a Negative Regulator of the MYC Pathway in Lung Adenocarcinoma. Llabata P, et al. Mol Cancer Res, 2020 Apr. PMID 31862696, Free PMC Article

    See all (119) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. In vivo CRISPR screens identify Mga as an immunotherapy target in triple-negative breast cancer.
      Title: In vivo CRISPR screens identify Mga as an immunotherapy target in triple-negative breast cancer.
    2. Functional characterization of cooperating MGA mutations in RUNX1::RUNX1T1 acute myeloid leukemia.
      Title: Functional characterization of cooperating MGA mutations in RUNX1::RUNX1T1 acute myeloid leukemia.
    3. Multi-Omics Analysis Identifies MGA as a Negative Regulator of the MYC Pathway in Lung Adenocarcinoma.
      Title: Multi-Omics Analysis Identifies MGA as a Negative Regulator of the MYC Pathway in Lung Adenocarcinoma.
    4. this study shows that LINE1 contributes to autoimmunity through both RIG-I- and MDA5-mediated RNA sensing pathways
      Title: LINE1 contributes to autoimmunity through both RIG-I- and MDA5-mediated RNA sensing pathways.
    5. we suggest that MGA loss-of-function mutations are present in colorectal cancers
      Title: Somatic mutation of a candidate tumour suppressor MGA gene and its mutational heterogeneity in colorectal cancers.
    6. In conclusion, our study generated five mAbs against MGA and identified the best candidate for detection of MGA expression in breast cancer tissues.
      Title: Generation of monoclonal antibodies against MGA and comparison of their application in breast cancer detection by immunohistochemistry.
    7. Results show that inactivation of MGA was observed in both non-small cell lung cancer and SCLC.
      Title: MAX inactivation in small cell lung cancer disrupts MYC-SWI/SNF programs and is synthetic lethal with BRG1.
    8. TLR3 and MDA5 signalling, although not expression, is impaired in asthmatic epithelial cells in response to rhinovirus infection.
      Title: TLR3 and MDA5 signalling, although not expression, is impaired in asthmatic epithelial cells in response to rhinovirus infection.
    Submit: New GeneRIF Correction

    Phenotypes

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    Find tests for this gene in the NIH Genetic Testing Registry (GTR)

    Review eQTL and phenotype association data in this region using PheGenI

    Variation

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    See variants in ClinVar

    See studies and variants in dbVar

    See Variation Viewer (GRCh37.p13)

    See Variation Viewer (GRCh38)

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Clone Names

    • FLJ12634, KIAA0518

    Gene Ontology Provided by GOA

    Function Evidence Code Pubs
    enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables DNA-binding transcription factor activity, RNA polymerase II-specific ISA
    Inferred from Sequence Alignment
    more info
    		  
    enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables protein dimerization activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in cell fate specification IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in positive regulation of DNA-templated transcription IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    part_of MLL1 complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of MLL1 complex IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in chromatin IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in chromatin ISA
    Inferred from Sequence Alignment
    more info
    		  
    located_in nucleoplasm TAS
    Traceable Author Statement
    more info
    		  
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    MAX gene-associated protein
    Names
    MAX dimerization protein 5
    MGA, MAX dimerization protein

    NCBI Reference Sequences (RefSeq)

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    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001080541.3 → NP_001074010.2  MAX gene-associated protein isoform 2

      Status: VALIDATED

      Source sequence(s)
      AA188751, AB011090, AC016134, AC073657, BC136659, BQ937819, BX643019, DC391039, DR001080
      Consensus CDS
      CCDS55960.1
      UniProtKB/TrEMBL
      A0A8C8P5L8
      Related
      ENSP00000456141.1, ENST00000566586.6
      Conserved Domains (3) summary
      cd00182
      Location:74 → 264
      TBOX; T-box DNA binding domain of the T-box family of transcriptional regulators. The T-box family is an ancient group that appears to play a critical role in development in all animal species. These genes were uncovered on the basis of similarity to the DNA ...
      pfam00010
      Location:2216 → 2266
      HLH; Helix-loop-helix DNA-binding domain
      pfam16059
      Location:1041 → 1087
      DUF4801; Domain of unknown function (DUF4801)

    2. NM_001164273.2 → NP_001157745.1  MAX gene-associated protein isoform 1

      Status: VALIDATED

      Source sequence(s)
      AC016134, AC073657
      Consensus CDS
      CCDS55959.1
      UniProtKB/Swiss-Prot
      B9EGR5, E7ENI0, F5H7K2, Q8IWI9, Q9H8R3, Q9H9N7, Q9UG69, Q9Y4E9
      UniProtKB/TrEMBL
      A0A8C8P5L8
      Related
      ENSP00000219905.7, ENST00000219905.13
      Conserved Domains (5) summary
      cd00182
      Location:74 → 264
      TBOX; T-box DNA binding domain of the T-box family of transcriptional regulators. The T-box family is an ancient group that appears to play a critical role in development in all animal species. These genes were uncovered on the basis of similarity to the DNA ...
      pfam03154
      Location:1689 → 1983
      Atrophin-1; Atrophin-1 family
      pfam16059
      Location:1041 → 1083
      DUF4801; Domain of unknown function (DUF4801)
      pfam17823
      Location:1469 → 1771
      DUF5585; Family of unknown function (DUF5585)
      cd18911
      Location:2425 → 2489
      bHLHzip_MGA; basic Helix-Loop-Helix-zipper (bHLHzip) domain found in MAX gene-associated protein (MGA) and similar proteins

    3. NM_001400225.1 → NP_001387154.1  MAX gene-associated protein isoform 3

      Status: VALIDATED

      Source sequence(s)
      AC016134, AC073657
      Consensus CDS
      CCDS91982.1
      UniProtKB/TrEMBL
      A0A8C8P5L8, A0A994J6L2
      Related
      ENSP00000515495.1, ENST00000703841.1

    4. NM_001400242.1 → NP_001387171.1  MAX gene-associated protein isoform 4

      Status: VALIDATED

      Source sequence(s)
      AC016134, AC073657

    5. NM_001400243.1 → NP_001387172.1  MAX gene-associated protein isoform 5

      Status: VALIDATED

      Source sequence(s)
      AC016134, AC073657
      Related
      ENST00000682463.1

    6. NM_001400244.1 → NP_001387173.1  MAX gene-associated protein isoform 5

      Status: VALIDATED

      Source sequence(s)
      AC016134, AC073657

    7. NM_001400245.1 → NP_001387174.1  MAX gene-associated protein isoform 5

      Status: VALIDATED

      Source sequence(s)
      AC016134, AC073657

    8. NM_001400246.1 → NP_001387175.1  MAX gene-associated protein isoform 5

      Status: VALIDATED

      Source sequence(s)
      AC016134, AC073657

    9. NM_001400247.1 → NP_001387176.1  MAX gene-associated protein isoform 5

      Status: VALIDATED

      Source sequence(s)
      AC016134, AC073657

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000015.10 Reference GRCh38.p14 Primary Assembly

      Range
      41621224..41769940
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_017022029.3 → XP_016877518.1  MAX gene-associated protein isoform X16

      Conserved Domains (2) summary
      pfam00010
      Location:2018 → 2068
      HLH; Helix-loop-helix DNA-binding domain
      pfam16059
      Location:584 → 630
      DUF4801; Domain of unknown function (DUF4801)

    2. XM_047432300.1 → XP_047288256.1  MAX gene-associated protein isoform X18

    3. XM_047432302.1 → XP_047288258.1  MAX gene-associated protein isoform X19

    4. XM_005254246.4 → XP_005254303.1  MAX gene-associated protein isoform X1

      See identical proteins and their annotated locations for XP_005254303.1

      UniProtKB/TrEMBL
      A0A8C8P5L8
      Conserved Domains (3) summary
      cd00182
      Location:74 → 264
      TBOX; T-box DNA binding domain of the T-box family of transcriptional regulators. The T-box family is an ancient group that appears to play a critical role in development in all animal species. These genes were uncovered on the basis of similarity to the DNA ...
      pfam00010
      Location:2475 → 2525
      HLH; Helix-loop-helix DNA-binding domain
      pfam16059
      Location:1041 → 1087
      DUF4801; Domain of unknown function (DUF4801)

    5. XM_047432276.1 → XP_047288232.1  MAX gene-associated protein isoform X2

      UniProtKB/TrEMBL
      A0A8C8P5L8, A0A994J6L2
      Related
      ENSP00000457035.2, ENST00000570161.6

    6. XM_047432286.1 → XP_047288242.1  MAX gene-associated protein isoform X9

      UniProtKB/TrEMBL
      A0A8C8P5L8

    7. XM_047432288.1 → XP_047288244.1  MAX gene-associated protein isoform X10

      UniProtKB/TrEMBL
      A0A8C8P5L8

    8. XM_047432279.1 → XP_047288235.1  MAX gene-associated protein isoform X3

      UniProtKB/TrEMBL
      A0A8C8P5L8

    9. XM_047432280.1 → XP_047288236.1  MAX gene-associated protein isoform X4

      UniProtKB/Swiss-Prot
      B9EGR5, E7ENI0, F5H7K2, Q8IWI9, Q9H8R3, Q9H9N7, Q9UG69, Q9Y4E9
      UniProtKB/TrEMBL
      A0A8C8P5L8

    10. XM_047432291.1 → XP_047288247.1  MAX gene-associated protein isoform X12

      UniProtKB/TrEMBL
      A0A8C8P5L8

    11. XM_047432281.1 → XP_047288237.1  MAX gene-associated protein isoform X6

      UniProtKB/TrEMBL
      A0A8C8P5L8

    12. XM_047432295.1 → XP_047288251.1  MAX gene-associated protein isoform X14

      UniProtKB/TrEMBL
      A0A8C8P5L8

    13. XM_047432298.1 → XP_047288254.1  MAX gene-associated protein isoform X15

      UniProtKB/TrEMBL
      A0A8C8P5L8

    14. XM_006720445.5 → XP_006720508.1  MAX gene-associated protein isoform X16

      Conserved Domains (2) summary
      pfam00010
      Location:2018 → 2068
      HLH; Helix-loop-helix DNA-binding domain
      pfam16059
      Location:584 → 630
      DUF4801; Domain of unknown function (DUF4801)

    15. XM_047432299.1 → XP_047288255.1  MAX gene-associated protein isoform X17

    16. XM_047432305.1 → XP_047288261.1  MAX gene-associated protein isoform X22

    17. XM_047432306.1 → XP_047288262.1  MAX gene-associated protein isoform X23

    18. XM_047432301.1 → XP_047288257.1  MAX gene-associated protein isoform X19

    19. XM_047432307.1 → XP_047288263.1  MAX gene-associated protein isoform X24

    20. XM_047432303.1 → XP_047288259.1  MAX gene-associated protein isoform X20

    21. XM_047432308.1 → XP_047288264.1  MAX gene-associated protein isoform X25

    22. XM_047432304.1 → XP_047288260.1  MAX gene-associated protein isoform X21

    23. XM_005254243.4 → XP_005254300.1  MAX gene-associated protein isoform X1

      See identical proteins and their annotated locations for XP_005254300.1

      UniProtKB/TrEMBL
      A0A8C8P5L8
      Conserved Domains (3) summary
      cd00182
      Location:74 → 264
      TBOX; T-box DNA binding domain of the T-box family of transcriptional regulators. The T-box family is an ancient group that appears to play a critical role in development in all animal species. These genes were uncovered on the basis of similarity to the DNA ...
      pfam00010
      Location:2475 → 2525
      HLH; Helix-loop-helix DNA-binding domain
      pfam16059
      Location:1041 → 1087
      DUF4801; Domain of unknown function (DUF4801)

    24. XM_005254253.4 → XP_005254310.1  MAX gene-associated protein isoform X9

      UniProtKB/TrEMBL
      A0A8C8P5L8
      Conserved Domains (3) summary
      cd00182
      Location:74 → 264
      TBOX; T-box DNA binding domain of the T-box family of transcriptional regulators. The T-box family is an ancient group that appears to play a critical role in development in all animal species. These genes were uncovered on the basis of similarity to the DNA ...
      pfam00010
      Location:2266 → 2316
      HLH; Helix-loop-helix DNA-binding domain
      pfam16059
      Location:1041 → 1087
      DUF4801; Domain of unknown function (DUF4801)

    25. XM_047432287.1 → XP_047288243.1  MAX gene-associated protein isoform X10

      UniProtKB/TrEMBL
      A0A8C8P5L8

    26. XM_005254249.4 → XP_005254306.1  MAX gene-associated protein isoform X3

      UniProtKB/TrEMBL
      A0A8C8P5L8
      Conserved Domains (3) summary
      cd00182
      Location:74 → 264
      TBOX; T-box DNA binding domain of the T-box family of transcriptional regulators. The T-box family is an ancient group that appears to play a critical role in development in all animal species. These genes were uncovered on the basis of similarity to the DNA ...
      pfam00010
      Location:2426 → 2476
      HLH; Helix-loop-helix DNA-binding domain
      pfam16059
      Location:1041 → 1087
      DUF4801; Domain of unknown function (DUF4801)

    27. XM_047432290.1 → XP_047288246.1  MAX gene-associated protein isoform X11

      UniProtKB/TrEMBL
      A0A8C8P5L8

    28. XM_011521397.4 → XP_011519699.1  MAX gene-associated protein isoform X5

      UniProtKB/TrEMBL
      A0A8C8P5L8
      Conserved Domains (3) summary
      cd00182
      Location:74 → 264
      TBOX; T-box DNA binding domain of the T-box family of transcriptional regulators. The T-box family is an ancient group that appears to play a critical role in development in all animal species. These genes were uncovered on the basis of similarity to the DNA ...
      pfam00010
      Location:2365 → 2415
      HLH; Helix-loop-helix DNA-binding domain
      pfam16059
      Location:1041 → 1087
      DUF4801; Domain of unknown function (DUF4801)

    29. XM_011521398.4 → XP_011519700.1  MAX gene-associated protein isoform X6

      UniProtKB/TrEMBL
      A0A8C8P5L8
      Conserved Domains (3) summary
      cd00182
      Location:74 → 264
      TBOX; T-box DNA binding domain of the T-box family of transcriptional regulators. The T-box family is an ancient group that appears to play a critical role in development in all animal species. These genes were uncovered on the basis of similarity to the DNA ...
      pfam00010
      Location:2364 → 2414
      HLH; Helix-loop-helix DNA-binding domain
      pfam16059
      Location:1041 → 1087
      DUF4801; Domain of unknown function (DUF4801)

    30. XM_047432292.1 → XP_047288248.1  MAX gene-associated protein isoform X13

      UniProtKB/TrEMBL
      A0A8C8P5L8

    31. XM_047432293.1 → XP_047288249.1  MAX gene-associated protein isoform X14

      UniProtKB/TrEMBL
      A0A8C8P5L8

    32. XM_005254252.4 → XP_005254309.1  MAX gene-associated protein isoform X7

      UniProtKB/TrEMBL
      A0A8C8P5L8
      Conserved Domains (3) summary
      cd00182
      Location:74 → 264
      TBOX; T-box DNA binding domain of the T-box family of transcriptional regulators. The T-box family is an ancient group that appears to play a critical role in development in all animal species. These genes were uncovered on the basis of similarity to the DNA ...
      pfam00010
      Location:2316 → 2366
      HLH; Helix-loop-helix DNA-binding domain
      pfam16059
      Location:1041 → 1087
      DUF4801; Domain of unknown function (DUF4801)

    33. XM_047432283.1 → XP_047288239.1  MAX gene-associated protein isoform X8

      UniProtKB/TrEMBL
      A0A8C8P5L8

    34. XM_047432297.1 → XP_047288253.1  MAX gene-associated protein isoform X15

      UniProtKB/TrEMBL
      A0A8C8P5L8

    35. XM_006720443.5 → XP_006720506.1  MAX gene-associated protein isoform X1

      See identical proteins and their annotated locations for XP_006720506.1

      UniProtKB/TrEMBL
      A0A8C8P5L8
      Conserved Domains (3) summary
      cd00182
      Location:74 → 264
      TBOX; T-box DNA binding domain of the T-box family of transcriptional regulators. The T-box family is an ancient group that appears to play a critical role in development in all animal species. These genes were uncovered on the basis of similarity to the DNA ...
      pfam00010
      Location:2475 → 2525
      HLH; Helix-loop-helix DNA-binding domain
      pfam16059
      Location:1041 → 1087
      DUF4801; Domain of unknown function (DUF4801)

    36. XM_047432278.1 → XP_047288234.1  MAX gene-associated protein isoform X2

      UniProtKB/TrEMBL
      A0A8C8P5L8, A0A994J6L2

    37. XM_047432289.1 → XP_047288245.1  MAX gene-associated protein isoform X10

      UniProtKB/TrEMBL
      A0A8C8P5L8

    38. XM_047432282.1 → XP_047288238.1  MAX gene-associated protein isoform X6

      UniProtKB/TrEMBL
      A0A8C8P5L8

    39. XM_047432296.1 → XP_047288252.1  MAX gene-associated protein isoform X14

      UniProtKB/TrEMBL
      A0A8C8P5L8

    40. XM_047432285.1 → XP_047288241.1  MAX gene-associated protein isoform X8

      UniProtKB/TrEMBL
      A0A8C8P5L8

    41. XM_047432310.1 → XP_047288266.1  MAX gene-associated protein isoform X29

    42. XM_047432312.1 → XP_047288268.1  MAX gene-associated protein isoform X30

    43. XM_047432309.1 → XP_047288265.1  MAX gene-associated protein isoform X28

    44. XM_047432311.1 → XP_047288267.1  MAX gene-associated protein isoform X30

    45. XM_047432313.1 → XP_047288269.1  MAX gene-associated protein isoform X31

    46. XM_005254254.5 → XP_005254311.1  MAX gene-associated protein isoform X26

      Conserved Domains (1) summary
      pfam00010
      Location:987 → 1037
      HLH; Helix-loop-helix DNA-binding domain

    47. XM_011521399.4 → XP_011519701.1  MAX gene-associated protein isoform X27

      See identical proteins and their annotated locations for XP_011519701.1

      Conserved Domains (1) summary
      pfam00010
      Location:924 → 974
      HLH; Helix-loop-helix DNA-binding domain

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060939.1 Alternate T2T-CHM13v2.0

      Range
      39427379..39575822
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_054377597.1 → XP_054233572.1  MAX gene-associated protein isoform X16

    2. XM_054377600.1 → XP_054233575.1  MAX gene-associated protein isoform X18

    3. XM_054377602.1 → XP_054233577.1  MAX gene-associated protein isoform X19

    4. XM_054377570.1 → XP_054233545.1  MAX gene-associated protein isoform X1

      UniProtKB/TrEMBL
      A0A8C8P5L8

    5. XM_054377572.1 → XP_054233547.1  MAX gene-associated protein isoform X2

      UniProtKB/TrEMBL
      A0A8C8P5L8

    6. XM_054377585.1 → XP_054233560.1  MAX gene-associated protein isoform X9

      UniProtKB/TrEMBL
      A0A8C8P5L8

    7. XM_054377587.1 → XP_054233562.1  MAX gene-associated protein isoform X10

      UniProtKB/TrEMBL
      A0A8C8P5L8

    8. XM_054377575.1 → XP_054233550.1  MAX gene-associated protein isoform X3

      UniProtKB/TrEMBL
      A0A8C8P5L8

    9. XM_054377576.1 → XP_054233551.1  MAX gene-associated protein isoform X4

      UniProtKB/TrEMBL
      A0A8C8P5L8

    10. XM_054377590.1 → XP_054233565.1  MAX gene-associated protein isoform X12

      UniProtKB/TrEMBL
      A0A8C8P5L8

    11. XM_054377579.1 → XP_054233554.1  MAX gene-associated protein isoform X6

      UniProtKB/TrEMBL
      A0A8C8P5L8

    12. XM_054377593.1 → XP_054233568.1  MAX gene-associated protein isoform X14

      UniProtKB/TrEMBL
      A0A8C8P5L8

    13. XM_054377596.1 → XP_054233571.1  MAX gene-associated protein isoform X15

      UniProtKB/TrEMBL
      A0A8C8P5L8

    14. XM_054377598.1 → XP_054233573.1  MAX gene-associated protein isoform X16

    15. XM_054377599.1 → XP_054233574.1  MAX gene-associated protein isoform X17

    16. XM_054377605.1 → XP_054233580.1  MAX gene-associated protein isoform X22

    17. XM_054377606.1 → XP_054233581.1  MAX gene-associated protein isoform X23

    18. XM_054377601.1 → XP_054233576.1  MAX gene-associated protein isoform X19

    19. XM_054377607.1 → XP_054233582.1  MAX gene-associated protein isoform X24

    20. XM_054377603.1 → XP_054233578.1  MAX gene-associated protein isoform X20

    21. XM_054377608.1 → XP_054233583.1  MAX gene-associated protein isoform X25

    22. XM_054377604.1 → XP_054233579.1  MAX gene-associated protein isoform X21

    23. XM_054377569.1 → XP_054233544.1  MAX gene-associated protein isoform X1

      UniProtKB/TrEMBL
      A0A8C8P5L8

    24. XM_054377584.1 → XP_054233559.1  MAX gene-associated protein isoform X9

      UniProtKB/TrEMBL
      A0A8C8P5L8

    25. XM_054377586.1 → XP_054233561.1  MAX gene-associated protein isoform X10

      UniProtKB/TrEMBL
      A0A8C8P5L8

    26. XM_054377574.1 → XP_054233549.1  MAX gene-associated protein isoform X3

      UniProtKB/TrEMBL
      A0A8C8P5L8

    27. XM_054377589.1 → XP_054233564.1  MAX gene-associated protein isoform X11

      UniProtKB/TrEMBL
      A0A8C8P5L8

    28. XM_054377577.1 → XP_054233552.1  MAX gene-associated protein isoform X5

      UniProtKB/TrEMBL
      A0A8C8P5L8

    29. XM_054377578.1 → XP_054233553.1  MAX gene-associated protein isoform X6

      UniProtKB/TrEMBL
      A0A8C8P5L8

    30. XM_054377591.1 → XP_054233566.1  MAX gene-associated protein isoform X13

      UniProtKB/TrEMBL
      A0A8C8P5L8

    31. XM_054377592.1 → XP_054233567.1  MAX gene-associated protein isoform X14

      UniProtKB/TrEMBL
      A0A8C8P5L8

    32. XM_054377581.1 → XP_054233556.1  MAX gene-associated protein isoform X7

      UniProtKB/TrEMBL
      A0A8C8P5L8

    33. XM_054377582.1 → XP_054233557.1  MAX gene-associated protein isoform X8

      UniProtKB/TrEMBL
      A0A8C8P5L8

    34. XM_054377595.1 → XP_054233570.1  MAX gene-associated protein isoform X15

      UniProtKB/TrEMBL
      A0A8C8P5L8

    35. XM_054377571.1 → XP_054233546.1  MAX gene-associated protein isoform X1

      UniProtKB/TrEMBL
      A0A8C8P5L8

    36. XM_054377573.1 → XP_054233548.1  MAX gene-associated protein isoform X2

      UniProtKB/TrEMBL
      A0A8C8P5L8

    37. XM_054377588.1 → XP_054233563.1  MAX gene-associated protein isoform X10

      UniProtKB/TrEMBL
      A0A8C8P5L8

    38. XM_054377580.1 → XP_054233555.1  MAX gene-associated protein isoform X6

      UniProtKB/TrEMBL
      A0A8C8P5L8

    39. XM_054377594.1 → XP_054233569.1  MAX gene-associated protein isoform X14

      UniProtKB/TrEMBL
      A0A8C8P5L8

    40. XM_054377583.1 → XP_054233558.1  MAX gene-associated protein isoform X8

      UniProtKB/TrEMBL
      A0A8C8P5L8

    41. XM_054377612.1 → XP_054233587.1  MAX gene-associated protein isoform X29

    42. XM_054377614.1 → XP_054233589.1  MAX gene-associated protein isoform X30

    43. XM_054377611.1 → XP_054233586.1  MAX gene-associated protein isoform X28

    44. XM_054377613.1 → XP_054233588.1  MAX gene-associated protein isoform X30

    45. XM_054377615.1 → XP_054233590.1  MAX gene-associated protein isoform X31

    46. XM_054377609.1 → XP_054233584.1  MAX gene-associated protein isoform X26

    47. XM_054377610.1 → XP_054233585.1  MAX gene-associated protein isoform X27

    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8IWI9.4 GenPept UniProtKB/Swiss-Prot:Q8IWI9

    Gene LinkOut

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