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    LINC00310 long intergenic non-protein coding RNA 310 [ Homo sapiens (human) ]

    Gene ID: 114036, updated on 10-Dec-2024

    Summary

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    Official Symbol
    LINC00310provided by HGNC
    Official Full Name
    long intergenic non-protein coding RNA 310provided by HGNC
    Primary source
    HGNC:HGNC:16414
    See related
    Ensembl:ENSG00000227456 AllianceGenome:HGNC:16414
    Gene type
    ncRNA
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    C21orf82; NCRNA00310
    Expression
    Low expression observed in reference dataset See more
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    Genomic context

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    See LINC00310 in Genome Data Viewer
    Location:
    21q22.11
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 21 NC_000021.9 (34180677..34189919)
    RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 21 NC_060945.1 (32562758..32572000)
    RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 21 NC_000021.8 (35552978..35562220)

    Chromosome 21 - NC_000021.9Genomic Context describing neighboring genes Neighboring gene H3K27ac hESC enhancer GRCh37_chr21:35445789-35446739 Neighboring gene solute carrier family 5 member 3 Neighboring gene mitochondrial ribosomal protein S6 Neighboring gene H3K27ac hESC enhancer GRCh37_chr21:35501946-35502490 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr21:35531196-35531696 Neighboring gene RPS5 pseudogene 2 Neighboring gene NANOG hESC enhancer GRCh37_chr21:35551498-35552375 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 18394 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr21:35575958-35576956 Neighboring gene VISTA enhancer hs2174 Neighboring gene uncharacterized LOC105372791 Neighboring gene Sharpr-MPRA regulatory region 13847 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr21:35755873-35756380 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr21:35756381-35756886 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr21:35756972-35757494 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr21:35757495-35758015 Neighboring gene potassium voltage-gated channel subfamily E regulatory subunit 2 Neighboring gene small integral membrane protein 11

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: HPA RNA-seq normal tissues
    • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
    • BioProject: PRJEB4337
    • Publication: PMID 24309898
    • Analysis date: Wed Apr 4 07:08:55 2018

    Bibliography

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    Related articles in PubMed

    1. [Role of LINC00310 in the glycidyl methacrylate-induced malignant transformation of human bronchial epithelial cell]. Ma S, et al. Wei Sheng Yan Jiu, 2020 Sep. PMID 33070810
    2. The oncogenic potentials and diagnostic significance of long non-coding RNA LINC00310 in breast cancer. Li J, et al. J Cell Mol Med, 2018 Sep. PMID 29993199, Free PMC Article
    3. Nineteen additional unpredicted transcripts from human chromosome 21. Reymond A, et al. Genomics, 2002 Jun. PMID 12036297
    4. The sequence of the human genome. Venter JC, et al. Science, 2001 Feb 16. PMID 11181995
    5. Complete sequencing and characterization of 21,243 full-length human cDNAs. Ota T, et al. Nat Genet, 2004 Jan. PMID 14702039

    See all (7) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. [Role of LINC00310 in the glycidyl methacrylate-induced malignant transformation of human bronchial epithelial cell].
      Title: [Role of LINC00310 in the glycidyl methacrylate-induced malignant transformation of human bronchial epithelial cell].
    2. Long non-coding RNA LINC00310 promoted cell proliferation by regulating c-Myc expression in vitro.
      Title: The oncogenic potentials and diagnostic significance of long non-coding RNA LINC00310 in breast cancer.
    Submit: New GeneRIF Correction

    Phenotypes

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    Review eQTL and phenotype association data in this region using PheGenI

    Variation

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    See variants in ClinVar

    See studies and variants in dbVar

    See Variation Viewer (GRCh37.p13)

    See Variation Viewer (GRCh38)

    General gene information

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    Markers

    Clone Names

    • FLJ35385, MGC138201

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    RNA

    1. NR_027266.1 RNA Sequence

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longer transcript.
      Source sequence(s)
      AF426258, AK092704

    2. NR_027267.1 RNA Sequence

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) uses an alternate 3' exon, compared to variant 1.
      Source sequence(s)
      AF426258
      Related
      ENST00000428914.2

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000021.9 Reference GRCh38.p14 Primary Assembly

      Range
      34180677..34189919
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060945.1 Alternate T2T-CHM13v2.0

      Range
      32562758..32572000
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Suppressed Reference Sequence(s)

    The following Reference Sequences have been suppressed. Explain

    1. NM_153751.1: Suppressed sequence

      Description
      NM_153751.1: This RefSeq was permanently suppressed because currently there is support for the transcript but not for the protein.
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P59036.1 GenPept UniProtKB/Swiss-Prot:P59036

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Chemical Information
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    Research Materials