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    UTY ubiquitously transcribed tetratricopeptide repeat containing, Y-linked [ Homo sapiens (human) ]

    Gene ID: 7404, updated on 9-Nov-2024

    Summary

    Official Symbol
    UTYprovided by HGNC
    Official Full Name
    ubiquitously transcribed tetratricopeptide repeat containing, Y-linkedprovided by HGNC
    Primary source
    HGNC:HGNC:12638
    See related
    Ensembl:ENSG00000183878 MIM:400009; AllianceGenome:HGNC:12638
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    UTY1; KDM6C; KDM6AL
    Summary
    This gene encodes a protein containing tetratricopeptide repeats which are thought to be involved in protein-protein interactions. The encoded protein is also a minor histocompatibility antigen which may induce graft rejection of male stem cell grafts. A large number of alternatively spliced transcripts have been observed for this gene, but the full length nature of some of these variants has not been determined. [provided by RefSeq, Apr 2012]
    Expression
    Broad expression in prostate (RPKM 1.9), small intestine (RPKM 1.4) and 20 other tissues See more
    Orthologs
    NEW
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    Genomic context

    See UTY in Genome Data Viewer
    Location:
    Yq11.221
    Exon count:
    44
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCh38.p14 (GCF_000001405.40) Y NC_000024.10 (13233895..13480670, complement)
    RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) Y NC_060948.1 (14140601..14387359, complement)
    RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) Y NC_000024.9 (15345776..15592550, complement)

    Chromosome Y - NC_000024.10Genomic Context describing neighboring genes Neighboring gene TGF-beta activated kinase 1/MAP3K7 binding protein 3 pseudogene 1 Neighboring gene developmental pluripotency associated 2 pseudogene 1 Neighboring gene proteasome subunit alpha 6 pseudogene 1 Neighboring gene microRNA 12120 Neighboring gene H3K27ac hESC enhancer GRCh37_chrY:15676931-15677431 Neighboring gene PSIP1 pseudogene 2 Neighboring gene thymosin beta 4 Y-linked

    Genomic regions, transcripts, and products

    Expression

    • Project title: HPA RNA-seq normal tissues
    • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
    • BioProject: PRJEB4337
    • Publication: PMID 24309898
    • Analysis date: Wed Apr 4 07:08:55 2018

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    HIV-1 interactions

    Replication interactions

    Interaction Pubs
    Knockdown of ubiquitously transcribed tetratricopeptide repeat gene, Y-linked (UTY) by siRNA inhibits HIV-1 replication in HeLa P4/R5 cells PubMed

    Go to the HIV-1, Human Interaction Database

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Clone Names

    • DKFZp686L12190

    Gene Ontology Provided by GOA

    Function Evidence Code Pubs
    enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables chromatin DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables histone H3K27me2/H3K27me3 demethylase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables histone demethylase activity TAS
    Traceable Author Statement
    more info
     
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    involved_in chromatin remodeling IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in heart development IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in regulation of gene expression IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    part_of MLL3/4 complex IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in nucleoplasm TAS
    Traceable Author Statement
    more info
     

    General protein information

    Preferred Names
    histone demethylase UTY
    Names
    [histone H3]-trimethyl-L-lysine(27) demethylase UTY
    ubiquitous TPR motif protein UTY
    ubiquitously transcribed TPR gene on Y chromosome
    ubiquitously transcribed tetratricopeptide repeat gene, Y chromosome
    ubiquitously transcribed tetratricopeptide repeat gene, Y-linked
    ubiquitously-transcribed TPR protein on the Y chromosome
    ubiquitously-transcribed Y chromosome tetratricopeptide repeat protein
    NP_001245178.1
    NP_001245179.1
    NP_001245180.1
    NP_001245181.1
    NP_001245182.1
    NP_001245183.1
    NP_001245184.1
    NP_001245185.1
    NP_001245186.1
    NP_001245187.1
    NP_001245188.1
    NP_001245189.1
    NP_001245190.1
    NP_001245191.1
    NP_001245192.1
    NP_001245193.1
    NP_001245194.1
    NP_001245195.1
    NP_001245196.1
    NP_001245197.1
    NP_001245198.1
    NP_001245199.1
    NP_001387099.1
    NP_001387100.1
    NP_001387102.1
    NP_001387104.1
    NP_001387106.1
    NP_001387107.1
    NP_001387110.1
    NP_001387112.1
    NP_001387114.1
    NP_001387116.1
    NP_001387118.1
    NP_001387121.1
    NP_001387124.1
    NP_001387128.1
    NP_001406735.1
    NP_009056.3
    NP_872600.1
    NP_872601.1
    XP_011529743.1
    XP_011529744.1
    XP_011529745.1
    XP_011529747.1
    XP_011529748.1
    XP_011529749.1
    XP_011529750.1
    XP_011529755.1
    XP_011529756.1
    XP_011529757.1
    XP_011529761.1
    XP_011529762.1
    XP_016885559.1
    XP_016885560.1
    XP_016885562.1
    XP_047298702.1
    XP_047298703.1
    XP_047298704.1
    XP_047298705.1
    XP_047298706.1
    XP_047298707.1
    XP_047298708.1
    XP_047298709.1
    XP_047298710.1
    XP_047298711.1
    XP_047298712.1
    XP_047298713.1
    XP_054184308.1
    XP_054184309.1
    XP_054184310.1
    XP_054184311.1
    XP_054184312.1
    XP_054184313.1
    XP_054184314.1
    XP_054184315.1
    XP_054184317.1
    XP_054184318.1
    XP_054184319.1
    XP_054184320.1
    XP_054184321.1
    XP_054184322.1
    XP_054184323.1
    XP_054184324.1
    XP_054184325.1
    XP_054184326.1
    XP_054184327.1
    XP_054184328.1
    XP_054184329.1
    XP_054184330.1
    XP_054184331.1
    XP_054184332.1
    XP_054184333.1
    XP_054184334.1
    XP_054184335.1

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001258249.2NP_001245178.1  histone demethylase UTY isoform 4

      Status: REVIEWED

      Description
      Transcript Variant: This variant (4) encodes the longest isoform (4).
      Source sequence(s)
      AC006376, AC010877
      Consensus CDS
      CCDS76079.1
      UniProtKB/TrEMBL
      F4MH35, F5H8B4
      Related
      ENSP00000442047.2, ENST00000545955.6
      Conserved Domains (7) summary
      pfam02373
      Location:11771285
      JmjC; JmjC domain, hydroxylase
      smart00558
      Location:11431207
      JmjC; A domain family that is part of the cupin metalloenzyme superfamily
      sd00006
      Location:282309
      TPR; TPR repeat [structural motif]
      pfam00515
      Location:315348
      TPR_1; Tetratricopeptide repeat
      pfam13414
      Location:314375
      TPR_11; TPR repeat
      pfam13424
      Location:202279
      TPR_12; Tetratricopeptide repeat
      pfam13431
      Location:269300
      TPR_17; Tetratricopeptide repeat
    2. NM_001258250.1NP_001245179.1  histone demethylase UTY isoform 5

      Status: REVIEWED

      Description
      Transcript Variant: This variant (5) has multiple differences in the coding region, but maintains the reading frame, compared to variant 4. The encoded isoform (5) is shorter than isoform 4.
      Source sequence(s)
      AC006376, AC010877, AY934850
      UniProtKB/TrEMBL
      E1NZ93
      Conserved Domains (6) summary
      pfam02373
      Location:9401048
      JmjC; JmjC domain, hydroxylase
      smart00558
      Location:906970
      JmjC; A domain family that is part of the cupin metalloenzyme superfamily
      sd00006
      Location:240275
      TPR; TPR repeat [structural motif]
      pfam00515
      Location:299332
      TPR_1; Tetratricopeptide repeat
      pfam13414
      Location:298359
      TPR_11; TPR repeat
      pfam13424
      Location:202279
      TPR_12; Tetratricopeptide repeat
    3. NM_001258251.1NP_001245180.1  histone demethylase UTY isoform 6

      Status: REVIEWED

      Description
      Transcript Variant: This variant (6) has multiple differences in the coding region, but maintains the reading frame, compared to variant 4. The encoded isoform (6) is shorter than isoform 4.
      Source sequence(s)
      AC006376, AC010877, DQ140388
      Consensus CDS
      CCDS76075.1
      UniProtKB/TrEMBL
      E1U198, F5H3N7
      Related
      ENSP00000445274.2, ENST00000538878.6
      Conserved Domains (7) summary
      pfam02373
      Location:10961204
      JmjC; JmjC domain, hydroxylase
      smart00558
      Location:10621126
      JmjC; A domain family that is part of the cupin metalloenzyme superfamily
      sd00006
      Location:282309
      TPR; TPR repeat [structural motif]
      pfam00515
      Location:315348
      TPR_1; Tetratricopeptide repeat
      pfam13414
      Location:314375
      TPR_11; TPR repeat
      pfam13424
      Location:202279
      TPR_12; Tetratricopeptide repeat
      pfam13431
      Location:269300
      TPR_17; Tetratricopeptide repeat
    4. NM_001258252.1NP_001245181.1  histone demethylase UTY isoform 7

      Status: REVIEWED

      Description
      Transcript Variant: This variant (7) lacks an exon in the coding region, but maintains the reading frame, compared to variant 4. The encoded isoform (7) is shorter than isoform 4.
      Source sequence(s)
      AC006376, AC010877, DQ140389
      Consensus CDS
      CCDS59184.1
      UniProtKB/TrEMBL
      F4MH92
      Related
      ENSP00000507736.1, ENST00000682913.1
      Conserved Domains (7) summary
      pfam02373
      Location:11251233
      JmjC; JmjC domain, hydroxylase
      smart00558
      Location:10911155
      JmjC; A domain family that is part of the cupin metalloenzyme superfamily
      sd00006
      Location:282309
      TPR; TPR repeat [structural motif]
      pfam00515
      Location:315348
      TPR_1; Tetratricopeptide repeat
      pfam13414
      Location:314375
      TPR_11; TPR repeat
      pfam13424
      Location:202279
      TPR_12; Tetratricopeptide repeat
      pfam13431
      Location:269300
      TPR_17; Tetratricopeptide repeat
    5. NM_001258253.1NP_001245182.1  histone demethylase UTY isoform 8

      Status: REVIEWED

      Description
      Transcript Variant: This variant (8) has multiple differences in the coding region, but maintains the reading frame, compared to variant 4. The encoded isoform (8) is shorter than isoform 4.
      Source sequence(s)
      AC006376, AC010877, DQ350457
      UniProtKB/TrEMBL
      E1U1M9
      Conserved Domains (7) summary
      pfam02373
      Location:10961204
      JmjC; JmjC domain, hydroxylase
      smart00558
      Location:10621126
      JmjC; A domain family that is part of the cupin metalloenzyme superfamily
      sd00006
      Location:282309
      TPR; TPR repeat [structural motif]
      pfam00515
      Location:315348
      TPR_1; Tetratricopeptide repeat
      pfam13414
      Location:314375
      TPR_11; TPR repeat
      pfam13424
      Location:202279
      TPR_12; Tetratricopeptide repeat
      pfam13431
      Location:269300
      TPR_17; Tetratricopeptide repeat
    6. NM_001258254.1NP_001245183.1  histone demethylase UTY isoform 9

      Status: REVIEWED

      Description
      Transcript Variant: This variant (9) has multiple differences in the coding region, but maintains the reading frame, compared to variant 4. The encoded isoform (9) is shorter than isoform 4.
      Source sequence(s)
      AC006376, AC010877, DQ140390
      Consensus CDS
      CCDS59185.1
      UniProtKB/TrEMBL
      F4MH29
      Related
      ENSP00000485539.2, ENST00000624098.3
      Conserved Domains (7) summary
      pfam02373
      Location:10011109
      JmjC; JmjC domain, hydroxylase
      smart00558
      Location:9671031
      JmjC; A domain family that is part of the cupin metalloenzyme superfamily
      sd00006
      Location:282309
      TPR; TPR repeat [structural motif]
      pfam00515
      Location:315348
      TPR_1; Tetratricopeptide repeat
      pfam13414
      Location:314375
      TPR_11; TPR repeat
      pfam13424
      Location:202279
      TPR_12; Tetratricopeptide repeat
      pfam13431
      Location:269300
      TPR_17; Tetratricopeptide repeat
    7. NM_001258255.1NP_001245184.1  histone demethylase UTY isoform 10

      See identical proteins and their annotated locations for NP_001245184.1

      Status: REVIEWED

      Description
      Transcript Variant: This variant (10) has multiple differences in the coding region, but maintains the reading frame, compared to variant 4. The encoded isoform (10) is shorter than isoform 4.
      Source sequence(s)
      AC006376, AC010877, EF612660
      UniProtKB/TrEMBL
      F4MH27, F4MH29
      Conserved Domains (7) summary
      pfam02373
      Location:10011109
      JmjC; JmjC domain, hydroxylase
      smart00558
      Location:9671031
      JmjC; A domain family that is part of the cupin metalloenzyme superfamily
      sd00006
      Location:282309
      TPR; TPR repeat [structural motif]
      pfam00515
      Location:315348
      TPR_1; Tetratricopeptide repeat
      pfam13414
      Location:314375
      TPR_11; TPR repeat
      pfam13424
      Location:202279
      TPR_12; Tetratricopeptide repeat
      pfam13431
      Location:269300
      TPR_17; Tetratricopeptide repeat
    8. NM_001258256.1NP_001245185.1  histone demethylase UTY isoform 11

      Status: REVIEWED

      Description
      Transcript Variant: This variant (11) lacks two exons in the coding region, but maintains the reading frame, compared to variant 4. The encoded isoform (11) is shorter than isoform 4.
      Source sequence(s)
      AC006376, AC010877, EF612663
      Consensus CDS
      CCDS76078.1
      UniProtKB/TrEMBL
      A0A096LPD8, F4MH30
      Related
      ENSP00000439922.2, ENST00000537580.6
      Conserved Domains (7) summary
      pfam02373
      Location:11251233
      JmjC; JmjC domain, hydroxylase
      smart00558
      Location:10911155
      JmjC; A domain family that is part of the cupin metalloenzyme superfamily
      sd00006
      Location:282309
      TPR; TPR repeat [structural motif]
      pfam00515
      Location:315348
      TPR_1; Tetratricopeptide repeat
      pfam13414
      Location:314375
      TPR_11; TPR repeat
      pfam13424
      Location:202279
      TPR_12; Tetratricopeptide repeat
      pfam13431
      Location:269300
      TPR_17; Tetratricopeptide repeat
    9. NM_001258257.1NP_001245186.1  histone demethylase UTY isoform 12

      Status: REVIEWED

      Description
      Transcript Variant: This variant (12) has multiple differences in the coding region, but maintains the reading frame, compared to variant 4. The encoded isoform (12) is shorter than isoform 4.
      Source sequence(s)
      AC006376, AC010877, EF612664
      UniProtKB/TrEMBL
      F4MH31
      Conserved Domains (7) summary
      pfam02373
      Location:9561064
      JmjC; JmjC domain, hydroxylase
      smart00558
      Location:922986
      JmjC; A domain family that is part of the cupin metalloenzyme superfamily
      sd00006
      Location:282309
      TPR; TPR repeat [structural motif]
      pfam00515
      Location:315348
      TPR_1; Tetratricopeptide repeat
      pfam13414
      Location:314375
      TPR_11; TPR repeat
      pfam13424
      Location:202279
      TPR_12; Tetratricopeptide repeat
      pfam13431
      Location:269300
      TPR_17; Tetratricopeptide repeat
    10. NM_001258258.1NP_001245187.1  histone demethylase UTY isoform 13

      Status: REVIEWED

      Description
      Transcript Variant: This variant (13) lacks an exon in the coding region, but maintains the reading frame, compared to variant 4. The encoded isoform (13) is shorter than isoform 4.
      Source sequence(s)
      AC006376, AC010877, EF612673
      Consensus CDS
      CCDS76076.1
      UniProtKB/TrEMBL
      A0A087X0Y2, F4MH40
      Related
      ENSP00000483735.1, ENST00000617789.5
      Conserved Domains (7) summary
      pfam02373
      Location:11321240
      JmjC; JmjC domain, hydroxylase
      smart00558
      Location:10981162
      JmjC; A domain family that is part of the cupin metalloenzyme superfamily
      sd00006
      Location:282309
      TPR; TPR repeat [structural motif]
      pfam00515
      Location:315348
      TPR_1; Tetratricopeptide repeat
      pfam13414
      Location:314375
      TPR_11; TPR repeat
      pfam13424
      Location:202279
      TPR_12; Tetratricopeptide repeat
      pfam13431
      Location:269300
      TPR_17; Tetratricopeptide repeat
    11. NM_001258259.1NP_001245188.1  histone demethylase UTY isoform 14

      Status: REVIEWED

      Description
      Transcript Variant: This variant (14) has multiple differences in the coding region, but maintains the reading frame, compared to variant 4. The encoded isoform (14) is shorter than isoform 4.
      Source sequence(s)
      AC006376, AC010877, EF612665
      UniProtKB/TrEMBL
      F4MH32
      Conserved Domains (6) summary
      pfam02373
      Location:10641172
      JmjC; JmjC domain, hydroxylase
      smart00558
      Location:10301094
      JmjC; A domain family that is part of the cupin metalloenzyme superfamily
      sd00006
      Location:240275
      TPR; TPR repeat [structural motif]
      pfam00515
      Location:299332
      TPR_1; Tetratricopeptide repeat
      pfam13414
      Location:298359
      TPR_11; TPR repeat
      pfam13424
      Location:202279
      TPR_12; Tetratricopeptide repeat
    12. NM_001258260.1NP_001245189.1  histone demethylase UTY isoform 15

      Status: REVIEWED

      Description
      Transcript Variant: This variant (15) has multiple differences in the coding region, but maintains the reading frame, compared to variant 4. The encoded isoform (15) is shorter than isoform 4.
      Source sequence(s)
      AC006376, AC010877, EF612680
      UniProtKB/TrEMBL
      F4MH47
      Conserved Domains (7) summary
      pfam02373
      Location:11101218
      JmjC; JmjC domain, hydroxylase
      smart00558
      Location:10761140
      JmjC; A domain family that is part of the cupin metalloenzyme superfamily
      sd00006
      Location:282309
      TPR; TPR repeat [structural motif]
      pfam00515
      Location:315348
      TPR_1; Tetratricopeptide repeat
      pfam13414
      Location:314375
      TPR_11; TPR repeat
      pfam13424
      Location:202279
      TPR_12; Tetratricopeptide repeat
      pfam13431
      Location:269300
      TPR_17; Tetratricopeptide repeat
    13. NM_001258261.1NP_001245190.1  histone demethylase UTY isoform 16

      Status: REVIEWED

      Description
      Transcript Variant: This variant (16) has multiple differences in the coding region, but maintains the reading frame, compared to variant 4. The encoded isoform (16) is shorter than isoform 4.
      Source sequence(s)
      AC006376, AC010877, EF612683
      Consensus CDS
      CCDS76074.1
      UniProtKB/TrEMBL
      F4MH50, F5GWV3
      Related
      ENSP00000441943.2, ENST00000540140.6
      Conserved Domains (5) summary
      pfam02373
      Location:11221230
      JmjC; JmjC domain, hydroxylase
      smart00558
      Location:10881152
      JmjC; A domain family that is part of the cupin metalloenzyme superfamily
      COG0457
      Location:103389
      TPR; Tetratricopeptide (TPR) repeat [General function prediction only]
      sd00006
      Location:240275
      TPR; TPR repeat [structural motif]
      pfam13431
      Location:269303
      TPR_17; Tetratricopeptide repeat
    14. NM_001258262.1NP_001245191.1  histone demethylase UTY isoform 17

      Status: REVIEWED

      Description
      Transcript Variant: This variant (17) uses an alternate splice site in the coding region, but maintains the reading frame, compared to variant 4. The encoded isoform (17) is shorter than isoform 4.
      Source sequence(s)
      AC006376, AC010877, EF612684
      UniProtKB/TrEMBL
      F4MH51
      Conserved Domains (7) summary
      pfam02373
      Location:10531161
      JmjC; JmjC domain, hydroxylase
      smart00558
      Location:10191083
      JmjC; A domain family that is part of the cupin metalloenzyme superfamily
      sd00006
      Location:282309
      TPR; TPR repeat [structural motif]
      pfam00515
      Location:315348
      TPR_1; Tetratricopeptide repeat
      pfam13414
      Location:314375
      TPR_11; TPR repeat
      pfam13424
      Location:202279
      TPR_12; Tetratricopeptide repeat
      pfam13431
      Location:269300
      TPR_17; Tetratricopeptide repeat
    15. NM_001258263.1NP_001245192.1  histone demethylase UTY isoform 18

      See identical proteins and their annotated locations for NP_001245192.1

      Status: REVIEWED

      Description
      Transcript Variant: This variant (18) lacks three exons in the coding region, but maintains the reading frame, compared to variant 4. The encoded isoform (18) is shorter than isoform 4.
      Source sequence(s)
      AC006376, AC010877, EF612693
      UniProtKB/TrEMBL
      E1U1M9, F4MH60
      Conserved Domains (7) summary
      pfam02373
      Location:10801188
      JmjC; JmjC domain, hydroxylase
      smart00558
      Location:10461110
      JmjC; A domain family that is part of the cupin metalloenzyme superfamily
      sd00006
      Location:282309
      TPR; TPR repeat [structural motif]
      pfam00515
      Location:315348
      TPR_1; Tetratricopeptide repeat
      pfam13414
      Location:314375
      TPR_11; TPR repeat
      pfam13424
      Location:202279
      TPR_12; Tetratricopeptide repeat
      pfam13431
      Location:269300
      TPR_17; Tetratricopeptide repeat
    16. NM_001258264.1NP_001245193.1  histone demethylase UTY isoform 19

      Status: REVIEWED

      Description
      Transcript Variant: This variant (19) has multiple differences in the coding region, but maintains the reading frame, compared to variant 4. The encoded isoform (19) is shorter than isoform 4.
      Source sequence(s)
      AC006376, AC010877, EF612695
      UniProtKB/TrEMBL
      F4MH62
      Conserved Domains (5) summary
      pfam02373
      Location:11091217
      JmjC; JmjC domain, hydroxylase
      smart00558
      Location:10751139
      JmjC; A domain family that is part of the cupin metalloenzyme superfamily
      COG0457
      Location:103406
      TPR; Tetratricopeptide (TPR) repeat [General function prediction only]
      sd00006
      Location:240275
      TPR; TPR repeat [structural motif]
      pfam00515
      Location:299332
      TPR_1; Tetratricopeptide repeat
    17. NM_001258265.1NP_001245194.1  histone demethylase UTY isoform 20

      Status: REVIEWED

      Description
      Transcript Variant: This variant (20) lacks six exons in the coding region, but maintains the reading frame, compared to variant 4. The encoded isoform (20) is shorter than isoform 4.
      Source sequence(s)
      AC006376, AC010877, EF653189
      Consensus CDS
      CCDS76073.1
      UniProtKB/TrEMBL
      A0A087X248, F4MH91
      Related
      ENSP00000484698.1, ENST00000618474.5
      Conserved Domains (7) summary
      pfam02373
      Location:9971105
      JmjC; JmjC domain, hydroxylase
      smart00558
      Location:9631027
      JmjC; A domain family that is part of the cupin metalloenzyme superfamily
      sd00006
      Location:199226
      TPR; TPR repeat [structural motif]
      pfam00515
      Location:232265
      TPR_1; Tetratricopeptide repeat
      pfam13414
      Location:231292
      TPR_11; TPR repeat
      pfam13424
      Location:194262
      TPR_12; Tetratricopeptide repeat
      pfam13431
      Location:186217
      TPR_17; Tetratricopeptide repeat
    18. NM_001258266.1NP_001245195.1  histone demethylase UTY isoform 21

      Status: REVIEWED

      Description
      Transcript Variant: This variant (21) lacks two exons in the coding region, but maintains the reading frame, compared to variant 4. The encoded isoform (21) is shorter than isoform 4.
      Source sequence(s)
      AC006376, AC010877, EF653190
      Consensus CDS
      CCDS76077.1
      UniProtKB/TrEMBL
      A0A087X2I9, F4MH92
      Related
      ENSP00000485013.1, ENST00000612274.5
      Conserved Domains (7) summary
      pfam02373
      Location:11001208
      JmjC; JmjC domain, hydroxylase
      smart00558
      Location:10661130
      JmjC; A domain family that is part of the cupin metalloenzyme superfamily
      sd00006
      Location:282309
      TPR; TPR repeat [structural motif]
      pfam00515
      Location:315348
      TPR_1; Tetratricopeptide repeat
      pfam13414
      Location:314375
      TPR_11; TPR repeat
      pfam13424
      Location:202279
      TPR_12; Tetratricopeptide repeat
      pfam13431
      Location:269300
      TPR_17; Tetratricopeptide repeat
    19. NM_001258267.1NP_001245196.1  histone demethylase UTY isoform 22

      Status: REVIEWED

      Description
      Transcript Variant: This variant (22) has multiple differences in the coding region, one of which results in a frameshift, compared to variant 4. The encoded isoform (22) is shorter and has a distinct C-terminus, compared to isoform 4.
      Source sequence(s)
      AC006376, AC010877, DQ341386
      UniProtKB/TrEMBL
      E1U1M3
      Conserved Domains (7) summary
      pfam02373
      Location:10801188
      JmjC; JmjC domain, hydroxylase
      smart00558
      Location:10461110
      JmjC; A domain family that is part of the cupin metalloenzyme superfamily
      sd00006
      Location:282309
      TPR; TPR repeat [structural motif]
      pfam00515
      Location:315348
      TPR_1; Tetratricopeptide repeat
      pfam13414
      Location:314375
      TPR_11; TPR repeat
      pfam13424
      Location:202279
      TPR_12; Tetratricopeptide repeat
      pfam13431
      Location:269300
      TPR_17; Tetratricopeptide repeat
    20. NM_001258268.1NP_001245197.1  histone demethylase UTY isoform 23

      Status: REVIEWED

      Description
      Transcript Variant: This variant (23) has multiple differences in the coding region, one of which results in a frameshift, compared to variant 4. The encoded isoform (23) is shorter and has a distinct C-terminus, compared to isoform 4.
      Source sequence(s)
      AC006376, AC010877, EF612662
      UniProtKB/TrEMBL
      F4MH29
      Conserved Domains (7) summary
      pfam02373
      Location:10011109
      JmjC; JmjC domain, hydroxylase
      smart00558
      Location:9671031
      JmjC; A domain family that is part of the cupin metalloenzyme superfamily
      sd00006
      Location:282309
      TPR; TPR repeat [structural motif]
      pfam00515
      Location:315348
      TPR_1; Tetratricopeptide repeat
      pfam13414
      Location:314375
      TPR_11; TPR repeat
      pfam13424
      Location:202279
      TPR_12; Tetratricopeptide repeat
      pfam13431
      Location:269300
      TPR_17; Tetratricopeptide repeat
    21. NM_001258269.1NP_001245198.1  histone demethylase UTY isoform 24

      Status: REVIEWED

      Description
      Transcript Variant: This variant (24) has multiple differences in the coding region, one of which results in a frameshift, compared to variant 4. The encoded isoform (24) is shorter and has a distinct C-terminus, compared to isoform 4.
      Source sequence(s)
      AC006376, AC010877, EF612679
      UniProtKB/TrEMBL
      F4MH46
      Conserved Domains (7) summary
      pfam02373
      Location:10311139
      JmjC; JmjC domain, hydroxylase
      smart00558
      Location:9971061
      JmjC; A domain family that is part of the cupin metalloenzyme superfamily
      sd00006
      Location:282309
      TPR; TPR repeat [structural motif]
      pfam00515
      Location:315348
      TPR_1; Tetratricopeptide repeat
      pfam13414
      Location:314375
      TPR_11; TPR repeat
      pfam13424
      Location:202279
      TPR_12; Tetratricopeptide repeat
      pfam13431
      Location:269300
      TPR_17; Tetratricopeptide repeat
    22. NM_001258270.1NP_001245199.1  histone demethylase UTY isoform 25

      Status: REVIEWED

      Description
      Transcript Variant: This variant (25) has multiple differences in the coding region, one of which results in a frameshift, compared to variant 4. The encoded isoform (25) is shorter and has a distinct C-terminus, compared to isoform 4.
      Source sequence(s)
      AC006376, AC010877, EF612669
      UniProtKB/TrEMBL
      F4MH36
      Conserved Domains (7) summary
      pfam02373
      Location:9561064
      JmjC; JmjC domain, hydroxylase
      smart00558
      Location:922986
      JmjC; A domain family that is part of the cupin metalloenzyme superfamily
      sd00006
      Location:282309
      TPR; TPR repeat [structural motif]
      pfam00515
      Location:315348
      TPR_1; Tetratricopeptide repeat
      pfam13414
      Location:314375
      TPR_11; TPR repeat
      pfam13424
      Location:202279
      TPR_12; Tetratricopeptide repeat
      pfam13431
      Location:269300
      TPR_17; Tetratricopeptide repeat
    23. NM_001400170.1NP_001387099.1  histone demethylase UTY isoform 26

      Status: REVIEWED

      Source sequence(s)
      AC006376, AC010877, AC244214
    24. NM_001400171.1NP_001387100.1  histone demethylase UTY isoform 27

      Status: REVIEWED

      Source sequence(s)
      AC006376, AC010877, AC244214
    25. NM_001400173.1NP_001387102.1  histone demethylase UTY isoform 28

      Status: REVIEWED

      Source sequence(s)
      AC006376, AC010877, AC244214
      Related
      ENSP00000507656.1, ENST00000682216.1
    26. NM_001400175.1NP_001387104.1  histone demethylase UTY isoform 29

      Status: REVIEWED

      Source sequence(s)
      AC006376, AC010877
      Consensus CDS
      CCDS94713.1
      UniProtKB/TrEMBL
      A0A8C8KHL4
      Related
      ENSP00000372352.5, ENST00000382896.9
    27. NM_001400177.1NP_001387106.1  histone demethylase UTY isoform 30

      Status: REVIEWED

      Source sequence(s)
      AC006376, AC010877
    28. NM_001400178.1NP_001387107.1  histone demethylase UTY isoform 31

      Status: REVIEWED

      Source sequence(s)
      AC006376, AC010877
    29. NM_001400181.1NP_001387110.1  histone demethylase UTY isoform 32

      Status: REVIEWED

      Source sequence(s)
      AC006376, AC010877
    30. NM_001400183.1NP_001387112.1  histone demethylase UTY isoform 33

      Status: REVIEWED

      Source sequence(s)
      AC006376, AC010877
    31. NM_001400185.1NP_001387114.1  histone demethylase UTY isoform 34

      Status: REVIEWED

      Source sequence(s)
      AC006376, AC010877
    32. NM_001400187.1NP_001387116.1  histone demethylase UTY isoform 35

      Status: REVIEWED

      Source sequence(s)
      AC006376, AC010877
    33. NM_001400189.1NP_001387118.1  histone demethylase UTY isoform 36

      Status: REVIEWED

      Source sequence(s)
      AC006376, AC010877
    34. NM_001400192.1NP_001387121.1  histone demethylase UTY isoform 37

      Status: REVIEWED

      Source sequence(s)
      AC006376, AC010877
      UniProtKB/TrEMBL
      F4MH58
    35. NM_001400195.1NP_001387124.1  histone demethylase UTY isoform 38

      Status: REVIEWED

      Source sequence(s)
      AC006376, AC010877
    36. NM_001400199.1NP_001387128.1  histone demethylase UTY isoform 39

      Status: REVIEWED

      Source sequence(s)
      AC006376, AC010877
    37. NM_001419806.1NP_001406735.1  histone demethylase UTY isoform 40

      Status: REVIEWED

      Source sequence(s)
      AC006376, AC010877, AC244214
    38. NM_007125.4NP_009056.3  histone demethylase UTY isoform 3

      See identical proteins and their annotated locations for NP_009056.3

      Status: REVIEWED

      Description
      Transcript Variant: This variant (3) lacks two consecutive exons in the coding region, but maintains the reading frame, compared to variant 4. The encoded isoform (3) is shorter than isoform 4.
      Source sequence(s)
      AC006376, AC010877, AF000994
      Consensus CDS
      CCDS14783.1
      UniProtKB/Swiss-Prot
      A8K9Z3, E1U199, E1U1A0, F5H4V7, F8W8R7, O14607, O14608
      UniProtKB/TrEMBL
      E1U198
      Related
      ENSP00000328939.4, ENST00000331397.8
      Conserved Domains (4) summary
      smart00558
      Location:10461110
      JmjC; A domain family that is part of the cupin metalloenzyme superfamily
      COG0457
      Location:103375
      TPR; Tetratricopeptide (TPR) repeat [General function prediction only]
      sd00006
      Location:282309
      TPR; TPR repeat [structural motif]
      pfam02373
      Location:10801188
      JmjC; JmjC domain, hydroxylase
    39. NM_182659.1NP_872600.1  histone demethylase UTY isoform 2

      Status: REVIEWED

      Description
      Transcript Variant: This variant (2) has multiple differences compared to variant 4, including the use of an alternate 3' UTR. The encoded isoform (2) is shorter than isoform 4.
      Source sequence(s)
      AF000995
      Consensus CDS
      CCDS14784.1
      UniProtKB/TrEMBL
      F4MH64
      Related
      ENSP00000355420.4, ENST00000362096.8
      Conserved Domains (7) summary
      pfam02373
      Location:10801188
      JmjC; JmjC domain, hydroxylase
      smart00558
      Location:10461110
      JmjC; A domain family that is part of the cupin metalloenzyme superfamily
      sd00006
      Location:282309
      TPR; TPR repeat [structural motif]
      pfam00515
      Location:315348
      TPR_1; Tetratricopeptide repeat
      pfam13414
      Location:314375
      TPR_11; TPR repeat
      pfam13424
      Location:202279
      TPR_12; Tetratricopeptide repeat
      pfam13431
      Location:269300
      TPR_17; Tetratricopeptide repeat
    40. NM_182660.1NP_872601.1  histone demethylase UTY isoform 1

      See identical proteins and their annotated locations for NP_872601.1

      Status: REVIEWED

      Description
      Transcript Variant: This variant (1) has multiple differences compared to variant 4, including the use of an alternate 3' UTR. The encoded isoform (1) is shorter and has a distinct C-terminus, compared to isoform 4.
      Source sequence(s)
      AF000996
      Consensus CDS
      CCDS14785.1
      UniProtKB/TrEMBL
      F4MH54
      Related
      ENSP00000330446.5, ENST00000329134.9
      Conserved Domains (6) summary
      sd00006
      Location:282309
      TPR; TPR repeat [structural motif]
      pfam00515
      Location:315348
      TPR_1; Tetratricopeptide repeat
      pfam13414
      Location:314375
      TPR_11; TPR repeat
      pfam13424
      Location:202279
      TPR_12; Tetratricopeptide repeat
      pfam13431
      Location:269300
      TPR_17; Tetratricopeptide repeat
      pfam13900
      Location:9961040
      GVQW; Putative domain of unknown function

    RNA

    1. NR_047596.1 RNA Sequence

      Status: REVIEWED

      Description
      Transcript Variant: This variant (26) lacks three internal exons compared to variant 4. This variant is represented as non-coding because the use of the 5'-most expected translational start codon renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).
      Source sequence(s)
      AC006376, AC010877, AY769065
    2. NR_047597.1 RNA Sequence

      Status: REVIEWED

      Description
      Transcript Variant: This variant (27) has multiple differences compared to variant 4. This variant is represented as non-coding because the use of the 5'-most expected translational start codon renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).
      Source sequence(s)
      AC006376, AC010877, AY769062
    3. NR_047598.1 RNA Sequence

      Status: REVIEWED

      Description
      Transcript Variant: This variant (28) has multiple differences compared to variant 4. This variant is represented as non-coding because the use of the 5'-most expected translational start codon renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).
      Source sequence(s)
      AC006376, AC010877, AY769061
    4. NR_047599.1 RNA Sequence

      Status: REVIEWED

      Description
      Transcript Variant: This variant (29) has multiple differences compared to variant 4. This variant is represented as non-coding because the use of the 5'-most expected translational start codon renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).
      Source sequence(s)
      AC006376, AC010877, DQ350459
    5. NR_047600.1 RNA Sequence

      Status: REVIEWED

      Description
      Transcript Variant: This variant (30) has multiple differences compared to variant 4. This variant is represented as non-coding because the use of the 5'-most expected translational start codon renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).
      Source sequence(s)
      AC006376, AC010877, DQ350456
    6. NR_047601.1 RNA Sequence

      Status: REVIEWED

      Description
      Transcript Variant: This variant (31) has multiple differences compared to variant 4. This variant is represented as non-coding because the use of the 5'-most expected translational start codon renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).
      Source sequence(s)
      AC006376, AC010877, EF653168
    7. NR_047602.1 RNA Sequence

      Status: REVIEWED

      Description
      Transcript Variant: This variant (32) lacks three internal exons compared to variant 4. This variant is represented as non-coding because the use of the 5'-most expected translational start codon renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).
      Source sequence(s)
      AC006376, AC010877, EF653182
    8. NR_047603.1 RNA Sequence

      Status: REVIEWED

      Description
      Transcript Variant: This variant (33) has multiple differences compared to variant 4. This variant is represented as non-coding because the use of the 5'-most expected translational start codon renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).
      Source sequence(s)
      AC006376, AC010877, EF653186
    9. NR_047604.1 RNA Sequence

      Status: REVIEWED

      Description
      Transcript Variant: This variant (34) has multiple differences compared to variant 4. This variant is represented as non-coding because the use of the 5'-most expected translational start codon renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).
      Source sequence(s)
      AC006376, AC010877, EF653191
    10. NR_047605.1 RNA Sequence

      Status: REVIEWED

      Description
      Transcript Variant: This variant (35) has multiple differences compared to variant 4. This variant is represented as non-coding because the use of the 5'-most expected translational start codon renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).
      Source sequence(s)
      AC006376, AC010877, EF653218
    11. NR_047606.1 RNA Sequence

      Status: REVIEWED

      Description
      Transcript Variant: This variant (36) has multiple differences compared to variant 4. This variant is represented as non-coding because the use of the 5'-most expected translational start codon renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).
      Source sequence(s)
      AC006376, AC010877, EF685283
    12. NR_047607.1 RNA Sequence

      Status: REVIEWED

      Description
      Transcript Variant: This variant (37) has multiple differences compared to variant 4. This variant is represented as non-coding because the use of the 5'-most expected translational start codon renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).
      Source sequence(s)
      AC006376, AC010877, EF653224
    13. NR_047608.1 RNA Sequence

      Status: REVIEWED

      Description
      Transcript Variant: This variant (38) has multiple differences compared to variant 4. This variant is represented as non-coding because the use of the 5'-most expected translational start codon renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).
      Source sequence(s)
      AC006376, AC010877, EF685285
    14. NR_047609.1 RNA Sequence

      Status: REVIEWED

      Description
      Transcript Variant: This variant (39) has multiple differences compared to variant 4. This variant is represented as non-coding because the use of the 5'-most expected translational start codon renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).
      Source sequence(s)
      AC006376, AC010877, EF685284
    15. NR_047610.1 RNA Sequence

      Status: REVIEWED

      Description
      Transcript Variant: This variant (40) has multiple differences compared to variant 4. This variant is represented as non-coding because the use of the 5'-most expected translational start codon renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).
      Source sequence(s)
      AC006376, AC010877, EF685287
    16. NR_047611.1 RNA Sequence

      Status: REVIEWED

      Description
      Transcript Variant: This variant (41) lacks two internal exons compared to variant 4. This variant is represented as non-coding because the use of the 5'-most expected translational start codon renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).
      Source sequence(s)
      AC006376, AC010877, EF685286
    17. NR_047612.1 RNA Sequence

      Status: REVIEWED

      Description
      Transcript Variant: This variant (42) lacks an internal exon compared to variant 4. This variant is represented as non-coding because the use of the 5'-most expected translational start codon renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).
      Source sequence(s)
      AC006376, AC010877, EF685288
    18. NR_047613.1 RNA Sequence

      Status: REVIEWED

      Description
      Transcript Variant: This variant (43) lacks three internal exons compared to variant 4. This variant is represented as non-coding because the use of the 5'-most expected translational start codon renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).
      Source sequence(s)
      AC006376, AC010877, EF685290
    19. NR_047614.1 RNA Sequence

      Status: REVIEWED

      Description
      Transcript Variant: This variant (44) has multiple differences compared to variant 4. This variant is represented as non-coding because the use of the 5'-most expected translational start codon renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).
      Source sequence(s)
      AC006376, AC010877, EF685291
    20. NR_047615.1 RNA Sequence

      Status: REVIEWED

      Description
      Transcript Variant: This variant (45) has multiple differences compared to variant 4. This variant is represented as non-coding because the use of the 5'-most expected translational start codon renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).
      Source sequence(s)
      AC006376, AC010877, EF685292
    21. NR_047616.1 RNA Sequence

      Status: REVIEWED

      Description
      Transcript Variant: This variant (46) has multiple differences compared to variant 4. This variant is represented as non-coding because the use of the 5'-most expected translational start codon renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).
      Source sequence(s)
      AC006376, AC010877, EF685293
    22. NR_047617.1 RNA Sequence

      Status: REVIEWED

      Description
      Transcript Variant: This variant (47) has multiple differences compared to variant 4. This variant is represented as non-coding because the use of the 5'-most expected translational start codon renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).
      Source sequence(s)
      AC006376, AC010877, EF685294
    23. NR_047618.1 RNA Sequence

      Status: REVIEWED

      Description
      Transcript Variant: This variant (48) has multiple differences compared to variant 4. This variant is represented as non-coding because the use of the 5'-most expected translational start codon renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).
      Source sequence(s)
      AC006376, AC010877, EF685295
    24. NR_047619.1 RNA Sequence

      Status: REVIEWED

      Description
      Transcript Variant: This variant (49) has multiple differences compared to variant 4. This variant is represented as non-coding because the use of the 5'-most expected translational start codon renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).
      Source sequence(s)
      AC006376, AC010877, EF685296
    25. NR_047620.1 RNA Sequence

      Status: REVIEWED

      Description
      Transcript Variant: This variant (50) lacks three internal exons compared to variant 4. This variant is represented as non-coding because the use of the 5'-most expected translational start codon renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).
      Source sequence(s)
      AC006376, AC010877, EF685297
    26. NR_047621.1 RNA Sequence

      Status: REVIEWED

      Description
      Transcript Variant: This variant (51) has multiple differences compared to variant 4. This variant is represented as non-coding because the use of the 5'-most expected translational start codon renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).
      Source sequence(s)
      AC006376, AC010877, EF685298
    27. NR_047622.1 RNA Sequence

      Status: REVIEWED

      Description
      Transcript Variant: This variant (52) lacks two internal exons compared to variant 4. This variant is represented as non-coding because the use of the 5'-most expected translational start codon renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).
      Source sequence(s)
      AC006376, AC010877, EF685300
    28. NR_047623.1 RNA Sequence

      Status: REVIEWED

      Description
      Transcript Variant: This variant (53) has multiple differences compared to variant 4. This variant is represented as non-coding because the use of the 5'-most expected translational start codon renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).
      Source sequence(s)
      AC006376, AC010877, EF685301
    29. NR_047624.1 RNA Sequence

      Status: REVIEWED

      Description
      Transcript Variant: This variant (54) has multiple differences compared to variant 4. This variant is represented as non-coding because the use of the 5'-most expected translational start codon renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).
      Source sequence(s)
      AC006376, AC010877, EF685307
    30. NR_047625.1 RNA Sequence

      Status: REVIEWED

      Description
      Transcript Variant: This variant (55) has multiple differences compared to variant 4. This variant is represented as non-coding because the use of the 5'-most expected translational start codon renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).
      Source sequence(s)
      AC006376, AC010877, EF685308
    31. NR_047626.1 RNA Sequence

      Status: REVIEWED

      Description
      Transcript Variant: This variant (56) has multiple differences compared to variant 4. This variant is represented as non-coding because the use of the 5'-most expected translational start codon renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).
      Source sequence(s)
      AC006376, AC010877, EF685309
    32. NR_047627.1 RNA Sequence

      Status: REVIEWED

      Description
      Transcript Variant: This variant (57) has multiple differences compared to variant 4. This variant is represented as non-coding because the use of the 5'-most expected translational start codon renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).
      Source sequence(s)
      AC006376, AC010877, EF685312
    33. NR_047628.1 RNA Sequence

      Status: REVIEWED

      Description
      Transcript Variant: This variant (58) has multiple differences compared to variant 4. This variant is represented as non-coding because the use of the 5'-most expected translational start codon renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).
      Source sequence(s)
      AC006376, AC010877, EF685314
    34. NR_047629.1 RNA Sequence

      Status: REVIEWED

      Description
      Transcript Variant: This variant (59) has multiple differences compared to variant 4. This variant is represented as non-coding because the use of the 5'-most expected translational start codon renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).
      Source sequence(s)
      AC006376, AC010877, EF685316
    35. NR_047630.1 RNA Sequence

      Status: REVIEWED

      Description
      Transcript Variant: This variant (60) lacks four internal exons compared to variant 4. This variant is represented as non-coding because the use of the 5'-most expected translational start codon renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).
      Source sequence(s)
      AC006376, AC010877, EF685342
    36. NR_047631.1 RNA Sequence

      Status: REVIEWED

      Description
      Transcript Variant: This variant (61) has multiple differences compared to variant 4. This variant is represented as non-coding because the use of the 5'-most expected translational start codon renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).
      Source sequence(s)
      AC006376, AC010877, EU026310
    37. NR_047632.1 RNA Sequence

      Status: REVIEWED

      Description
      Transcript Variant: This variant (62) has multiple differences compared to variant 4. This variant is represented as non-coding because the use of the 5'-most expected translational start codon renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).
      Source sequence(s)
      AC006376, AC010877, EU026316
    38. NR_047633.1 RNA Sequence

      Status: REVIEWED

      Description
      Transcript Variant: This variant (63) has multiple differences compared to variant 4. This variant is represented as non-coding because the use of the 5'-most expected translational start codon renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).
      Source sequence(s)
      AC006376, AC010877, EU026317
    39. NR_047634.1 RNA Sequence

      Status: REVIEWED

      Description
      Transcript Variant: This variant (64) has multiple differences compared to variant 4. This variant is represented as non-coding because the use of the 5'-most expected translational start codon renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).
      Source sequence(s)
      AC006376, AC010877, EU116348
    40. NR_047635.1 RNA Sequence

      Status: REVIEWED

      Description
      Transcript Variant: This variant (65) has multiple differences compared to variant 4. This variant is represented as non-coding because the use of the 5'-most expected translational start codon renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).
      Source sequence(s)
      AC006376, AC010877, EU116352
    41. NR_047636.1 RNA Sequence

      Status: REVIEWED

      Description
      Transcript Variant: This variant (66) has multiple differences compared to variant 4. This variant is represented as non-coding because the use of the 5'-most expected translational start codon renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).
      Source sequence(s)
      AC006376, AC010877, EU116353
    42. NR_047637.1 RNA Sequence

      Status: REVIEWED

      Description
      Transcript Variant: This variant (67) has multiple differences compared to variant 4. This variant is represented as non-coding because the use of the 5'-most expected translational start codon renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).
      Source sequence(s)
      AC006376, AC010877, EU163942
    43. NR_047638.1 RNA Sequence

      Status: REVIEWED

      Description
      Transcript Variant: This variant (68) has multiple differences compared to variant 4. This variant is represented as non-coding because the use of the 5'-most expected translational start codon renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).
      Source sequence(s)
      AC006376, AC010877, EU163941
    44. NR_047639.1 RNA Sequence

      Status: REVIEWED

      Description
      Transcript Variant: This variant (69) lacks four internal exons compared to variant 4. This variant is represented as non-coding because the use of the 5'-most expected translational start codon renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).
      Source sequence(s)
      AC006376, AC010877, EF653192
    45. NR_047640.1 RNA Sequence

      Status: REVIEWED

      Description
      Transcript Variant: This variant (70) has multiple differences compared to variant 4. This variant is represented as non-coding because the use of the 5'-most expected translational start codon renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).
      Source sequence(s)
      AC006376, AC010877, EF653193
    46. NR_047641.1 RNA Sequence

      Status: REVIEWED

      Description
      Transcript Variant: This variant (71) has multiple differences compared to variant 4. This variant is represented as non-coding because the use of the 5'-most expected translational start codon renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).
      Source sequence(s)
      AC006376, AC010877, EF653196
    47. NR_047642.1 RNA Sequence

      Status: REVIEWED

      Description
      Transcript Variant: This variant (72) has multiple differences compared to variant 4. This variant is represented as non-coding because the use of the 5'-most expected translational start codon renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).
      Source sequence(s)
      AC006376, AC010877, EF653198
    48. NR_047643.1 RNA Sequence

      Status: REVIEWED

      Description
      Transcript Variant: This variant (73) has multiple differences compared to variant 4. This variant is represented as non-coding because the use of the 5'-most expected translational start codon renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).
      Source sequence(s)
      AC006376, AC010877, EF653200
    49. NR_047644.1 RNA Sequence

      Status: REVIEWED

      Description
      Transcript Variant: This variant (74) uses an alternate splice site compared to variant 4. This variant is represented as non-coding because the use of the 5'-most expected translational start codon renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).
      Source sequence(s)
      AC006376, AC010877, EF653207
    50. NR_047645.1 RNA Sequence

      Status: REVIEWED

      Description
      Transcript Variant: This variant (75) has multiple differences compared to variant 4. This variant is represented as non-coding because the use of the 5'-most expected translational start codon renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).
      Source sequence(s)
      AC006376, AC010877, EF653209
    51. NR_047646.1 RNA Sequence

      Status: REVIEWED

      Description
      Transcript Variant: This variant (76) lacks three internal exons compared to variant 4. This variant is represented as non-coding because the use of the 5'-most expected translational start codon renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).
      Source sequence(s)
      AC006376, AC010877, EF653213
    52. NR_047647.1 RNA Sequence

      Status: REVIEWED

      Description
      Transcript Variant: This variant (77) has multiple differences compared to variant 4. This variant is represented as non-coding because the use of the 5'-most expected translational start codon renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).
      Source sequence(s)
      AC006376, AC010877, EF653217
    53. NR_174404.1 RNA Sequence

      Status: REVIEWED

      Source sequence(s)
      AC006376, AC010877, AC244214
    54. NR_174405.1 RNA Sequence

      Status: REVIEWED

      Source sequence(s)
      AC006376, AC010877
      Related
      ENST00000682112.1

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000024.10 Reference GRCh38.p14 Primary Assembly

      Range
      13233895..13480670 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_011531448.4XP_011529750.1  histone demethylase UTY isoform X8

      UniProtKB/TrEMBL
      A0A804HJV1
      Conserved Domains (7) summary
      pfam02373
      Location:11261234
      JmjC; JmjC domain, hydroxylase
      smart00558
      Location:10921156
      JmjC; A domain family that is part of the cupin metalloenzyme superfamily
      sd00006
      Location:282309
      TPR; TPR repeat [structural motif]
      pfam00515
      Location:315348
      TPR_1; Tetratricopeptide repeat
      pfam13414
      Location:314375
      TPR_11; TPR repeat
      pfam13424
      Location:202279
      TPR_12; Tetratricopeptide repeat
      pfam13431
      Location:269300
      TPR_17; Tetratricopeptide repeat
    2. XM_011531447.4XP_011529749.1  histone demethylase UTY isoform X7

      UniProtKB/TrEMBL
      A0A804HJV1
      Conserved Domains (7) summary
      pfam02373
      Location:11321240
      JmjC; JmjC domain, hydroxylase
      smart00558
      Location:10981162
      JmjC; A domain family that is part of the cupin metalloenzyme superfamily
      sd00006
      Location:282309
      TPR; TPR repeat [structural motif]
      pfam00515
      Location:315348
      TPR_1; Tetratricopeptide repeat
      pfam13414
      Location:314375
      TPR_11; TPR repeat
      pfam13424
      Location:202279
      TPR_12; Tetratricopeptide repeat
      pfam13431
      Location:269300
      TPR_17; Tetratricopeptide repeat
    3. XM_011531445.4XP_011529747.1  histone demethylase UTY isoform X5

      UniProtKB/TrEMBL
      A0A804HJV1
      Conserved Domains (7) summary
      pfam02373
      Location:11481256
      JmjC; JmjC domain, hydroxylase
      smart00558
      Location:11141178
      JmjC; A domain family that is part of the cupin metalloenzyme superfamily
      sd00006
      Location:282309
      TPR; TPR repeat [structural motif]
      pfam00515
      Location:315348
      TPR_1; Tetratricopeptide repeat
      pfam13414
      Location:314375
      TPR_11; TPR repeat
      pfam13424
      Location:202279
      TPR_12; Tetratricopeptide repeat
      pfam13431
      Location:269300
      TPR_17; Tetratricopeptide repeat
    4. XM_011531446.4XP_011529748.1  histone demethylase UTY isoform X6

      UniProtKB/TrEMBL
      A0A804HJV1
      Conserved Domains (7) summary
      pfam02373
      Location:11411249
      JmjC; JmjC domain, hydroxylase
      smart00558
      Location:11071171
      JmjC; A domain family that is part of the cupin metalloenzyme superfamily
      sd00006
      Location:282309
      TPR; TPR repeat [structural motif]
      pfam00515
      Location:315348
      TPR_1; Tetratricopeptide repeat
      pfam13414
      Location:314375
      TPR_11; TPR repeat
      pfam13424
      Location:202279
      TPR_12; Tetratricopeptide repeat
      pfam13431
      Location:269300
      TPR_17; Tetratricopeptide repeat
    5. XM_047442746.1XP_047298702.1  histone demethylase UTY isoform X4

    6. XM_011531443.4XP_011529745.1  histone demethylase UTY isoform X3

      UniProtKB/TrEMBL
      A0A804HJV1
      Conserved Domains (7) summary
      pfam02373
      Location:11711279
      JmjC; JmjC domain, hydroxylase
      smart00558
      Location:11371201
      JmjC; A domain family that is part of the cupin metalloenzyme superfamily
      sd00006
      Location:282309
      TPR; TPR repeat [structural motif]
      pfam00515
      Location:315348
      TPR_1; Tetratricopeptide repeat
      pfam13414
      Location:314375
      TPR_11; TPR repeat
      pfam13424
      Location:202279
      TPR_12; Tetratricopeptide repeat
      pfam13431
      Location:269300
      TPR_17; Tetratricopeptide repeat
    7. XM_011531442.4XP_011529744.1  histone demethylase UTY isoform X2

      UniProtKB/TrEMBL
      A0A804HJV1
      Conserved Domains (7) summary
      pfam02373
      Location:11771285
      JmjC; JmjC domain, hydroxylase
      smart00558
      Location:11431207
      JmjC; A domain family that is part of the cupin metalloenzyme superfamily
      sd00006
      Location:282309
      TPR; TPR repeat [structural motif]
      pfam00515
      Location:315348
      TPR_1; Tetratricopeptide repeat
      pfam13414
      Location:314375
      TPR_11; TPR repeat
      pfam13424
      Location:202279
      TPR_12; Tetratricopeptide repeat
      pfam13431
      Location:269300
      TPR_17; Tetratricopeptide repeat
    8. XM_011531441.4XP_011529743.1  histone demethylase UTY isoform X1

      UniProtKB/TrEMBL
      A0A804HJV1
      Conserved Domains (3) summary
      smart00558
      Location:11591223
      JmjC; A domain family that is part of the cupin metalloenzyme superfamily
      COG0457
      Location:103375
      TPR; Tetratricopeptide (TPR) repeat [General function prediction only]
      sd00006
      Location:282309
      TPR; TPR repeat [structural motif]
    9. XM_047442752.1XP_047298708.1  histone demethylase UTY isoform X18

    10. XM_047442754.1XP_047298710.1  histone demethylase UTY isoform X20

    11. XM_047442751.1XP_047298707.1  histone demethylase UTY isoform X17

    12. XM_047442749.1XP_047298705.1  histone demethylase UTY isoform X15

    13. XM_047442748.1XP_047298704.1  histone demethylase UTY isoform X14

    14. XM_047442750.1XP_047298706.1  histone demethylase UTY isoform X16

    15. XM_011531453.4XP_011529755.1  histone demethylase UTY isoform X10

      UniProtKB/TrEMBL
      F4MH35
      Conserved Domains (7) summary
      pfam02373
      Location:11931301
      JmjC; JmjC domain, hydroxylase
      smart00558
      Location:11591223
      JmjC; A domain family that is part of the cupin metalloenzyme superfamily
      sd00006
      Location:282309
      TPR; TPR repeat [structural motif]
      pfam00515
      Location:315348
      TPR_1; Tetratricopeptide repeat
      pfam13414
      Location:314375
      TPR_11; TPR repeat
      pfam13424
      Location:202279
      TPR_12; Tetratricopeptide repeat
      pfam13431
      Location:269300
      TPR_17; Tetratricopeptide repeat
    16. XM_011531455.4XP_011529757.1  histone demethylase UTY isoform X12

      See identical proteins and their annotated locations for XP_011529757.1

      UniProtKB/TrEMBL
      F4MH35
      Conserved Domains (7) summary
      pfam02373
      Location:11931301
      JmjC; JmjC domain, hydroxylase
      smart00558
      Location:11591223
      JmjC; A domain family that is part of the cupin metalloenzyme superfamily
      sd00006
      Location:282309
      TPR; TPR repeat [structural motif]
      pfam00515
      Location:315348
      TPR_1; Tetratricopeptide repeat
      pfam13414
      Location:314375
      TPR_11; TPR repeat
      pfam13424
      Location:202279
      TPR_12; Tetratricopeptide repeat
      pfam13431
      Location:269300
      TPR_17; Tetratricopeptide repeat
    17. XM_047442753.1XP_047298709.1  histone demethylase UTY isoform X19

    18. XM_047442747.1XP_047298703.1  histone demethylase UTY isoform X13

    19. XM_011531454.4XP_011529756.1  histone demethylase UTY isoform X11

      UniProtKB/TrEMBL
      F4MH35
      Conserved Domains (7) summary
      pfam02373
      Location:11931301
      JmjC; JmjC domain, hydroxylase
      smart00558
      Location:11591223
      JmjC; A domain family that is part of the cupin metalloenzyme superfamily
      sd00006
      Location:282309
      TPR; TPR repeat [structural motif]
      pfam00515
      Location:315348
      TPR_1; Tetratricopeptide repeat
      pfam13414
      Location:314375
      TPR_11; TPR repeat
      pfam13424
      Location:202279
      TPR_12; Tetratricopeptide repeat
      pfam13431
      Location:269300
      TPR_17; Tetratricopeptide repeat
    20. XM_047442755.1XP_047298711.1  histone demethylase UTY isoform X22

    21. XM_011531459.4XP_011529761.1  histone demethylase UTY isoform X21

      UniProtKB/TrEMBL
      F4MHC1
      Conserved Domains (7) summary
      pfam02373
      Location:11931301
      JmjC; JmjC domain, hydroxylase
      smart00558
      Location:11591223
      JmjC; A domain family that is part of the cupin metalloenzyme superfamily
      sd00006
      Location:282309
      TPR; TPR repeat [structural motif]
      pfam00515
      Location:315348
      TPR_1; Tetratricopeptide repeat
      pfam13414
      Location:314375
      TPR_11; TPR repeat
      pfam13424
      Location:202279
      TPR_12; Tetratricopeptide repeat
      pfam13431
      Location:269300
      TPR_17; Tetratricopeptide repeat
    22. XM_047442756.1XP_047298712.1  histone demethylase UTY isoform X25

    23. XM_017030070.3XP_016885559.1  histone demethylase UTY isoform X23

      UniProtKB/TrEMBL
      F4MHH6
    24. XM_017030071.3XP_016885560.1  histone demethylase UTY isoform X27

      UniProtKB/TrEMBL
      E1NZ81
    25. XM_017030073.3XP_016885562.1  histone demethylase UTY isoform X28

      UniProtKB/TrEMBL
      F4MH98
    26. XM_047442757.1XP_047298713.1  histone demethylase UTY isoform X26

    27. XM_011531460.4XP_011529762.1  histone demethylase UTY isoform X24

      UniProtKB/TrEMBL
      F4MH44
      Conserved Domains (6) summary
      sd00006
      Location:282309
      TPR; TPR repeat [structural motif]
      pfam00515
      Location:315348
      TPR_1; Tetratricopeptide repeat
      pfam13414
      Location:314375
      TPR_11; TPR repeat
      pfam13424
      Location:202279
      TPR_12; Tetratricopeptide repeat
      pfam13431
      Location:269300
      TPR_17; Tetratricopeptide repeat
      pfam13900
      Location:11091153
      GVQW; Putative domain of unknown function

    RNA

    1. XR_007068451.1 RNA Sequence

    2. XR_007068452.1 RNA Sequence

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060948.1 Alternate T2T-CHM13v2.0

      Range
      14140601..14387359 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_054328340.1XP_054184315.1  histone demethylase UTY isoform X8

    2. XM_054328339.1XP_054184314.1  histone demethylase UTY isoform X7

    3. XM_054328337.1XP_054184312.1  histone demethylase UTY isoform X5

    4. XM_054328338.1XP_054184313.1  histone demethylase UTY isoform X6

    5. XM_054328336.1XP_054184311.1  histone demethylase UTY isoform X4

    6. XM_054328335.1XP_054184310.1  histone demethylase UTY isoform X3

    7. XM_054328334.1XP_054184309.1  histone demethylase UTY isoform X2

    8. XM_054328333.1XP_054184308.1  histone demethylase UTY isoform X1

    9. XM_054328350.1XP_054184325.1  histone demethylase UTY isoform X18

    10. XM_054328352.1XP_054184327.1  histone demethylase UTY isoform X20

    11. XM_054328349.1XP_054184324.1  histone demethylase UTY isoform X17

    12. XM_054328347.1XP_054184322.1  histone demethylase UTY isoform X15

    13. XM_054328346.1XP_054184321.1  histone demethylase UTY isoform X14

    14. XM_054328348.1XP_054184323.1  histone demethylase UTY isoform X16

    15. XM_054328342.1XP_054184317.1  histone demethylase UTY isoform X10

    16. XM_054328344.1XP_054184319.1  histone demethylase UTY isoform X12

    17. XM_054328351.1XP_054184326.1  histone demethylase UTY isoform X19

    18. XM_054328345.1XP_054184320.1  histone demethylase UTY isoform X13

    19. XM_054328343.1XP_054184318.1  histone demethylase UTY isoform X11

    20. XM_054328354.1XP_054184329.1  histone demethylase UTY isoform X22

    21. XM_054328353.1XP_054184328.1  histone demethylase UTY isoform X21

    22. XM_054328357.1XP_054184332.1  histone demethylase UTY isoform X25

    23. XM_054328355.1XP_054184330.1  histone demethylase UTY isoform X23

    24. XM_054328359.1XP_054184334.1  histone demethylase UTY isoform X27

    25. XM_054328360.1XP_054184335.1  histone demethylase UTY isoform X28

    26. XM_054328358.1XP_054184333.1  histone demethylase UTY isoform X26

    27. XM_054328356.1XP_054184331.1  histone demethylase UTY isoform X24

    RNA

    1. XR_008485528.1 RNA Sequence

    2. XR_008485529.1 RNA Sequence