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    GALNT11 polypeptide N-acetylgalactosaminyltransferase 11 [ Homo sapiens (human) ]

    Gene ID: 63917, updated on 27-Nov-2024

    Summary

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    Official Symbol
    GALNT11provided by HGNC
    Official Full Name
    polypeptide N-acetylgalactosaminyltransferase 11provided by HGNC
    Primary source
    HGNC:HGNC:19875
    See related
    Ensembl:ENSG00000178234 MIM:615130; AllianceGenome:HGNC:19875
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    GALNACT11; GALNAC-T11
    Summary
    Enables Notch binding activity and polypeptide N-acetylgalactosaminyltransferase activity. Involved in protein O-linked glycosylation via threonine. Predicted to be located in Golgi membrane. Predicted to be active in Golgi apparatus. [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Broad expression in kidney (RPKM 69.9), placenta (RPKM 22.3) and 24 other tissues See more
    Orthologs
    mouse all
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    Genomic context

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    See GALNT11 in Genome Data Viewer
    Location:
    7q36.1; 7q36.1
    Exon count:
    25
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 7 NC_000007.14 (152025674..152122340)
    RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 7 NC_060931.1 (153198601..153295227)
    RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 7 NC_000007.13 (151722759..151819425)

    Chromosome 7 - NC_000007.14Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC105375571 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr7:151685205-151685733 Neighboring gene polypeptide N-acetylgalactosaminyltransferase like 5 Neighboring gene Sharpr-MPRA regulatory region 5574 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 18829 Neighboring gene NANOG hESC enhancer GRCh37_chr7:151735547-151736048 Neighboring gene small nucleolar RNA U13 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr7:151778343-151779337 Neighboring gene BRD4-independent group 4 enhancer GRCh37_chr7:151804574-151805773 Neighboring gene uncharacterized LOC731075 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 26876 Neighboring gene Y-box binding protein 1 pseudogene 4 Neighboring gene lysine methyltransferase 2C Neighboring gene MPRA-validated peak6855 silencer Neighboring gene Sharpr-MPRA regulatory region 15588 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 26877 Neighboring gene septin 7 pseudogene 6

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: HPA RNA-seq normal tissues
    • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
    • BioProject: PRJEB4337
    • Publication: PMID 24309898
    • Analysis date: Wed Apr 4 07:08:55 2018

    Bibliography

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    Related articles in PubMed

    1. GALNT11 as a new molecular marker in chronic lymphocytic leukemia. Libisch MG, et al. Gene, 2014 Jan 1. PMID 24076351
    2. Rescue of Drosophila Melanogaster l(2)35Aa lethality is only mediated by polypeptide GalNAc-transferase pgant35A, but not by the evolutionary conserved human ortholog GalNAc-transferase-T11. Bennett EP, et al. Glycoconj J, 2010 May. PMID 20422447
    3. A Japanese-specific allele in the GALNT11 gene. Yuasa I, et al. Leg Med (Tokyo), 2010 Jul. PMID 20547088
    4. The heterotaxy gene GALNT11 glycosylates Notch to orchestrate cilia type and laterality. Boskovski MT, et al. Nature, 2013 Dec 19. PMID 24226769, Free PMC Article
    5. Genome-wide association study of kidney function decline in individuals of European descent. Gorski M, et al. Kidney Int, 2015 May. PMID 25493955, Free PMC Article

    See all (24) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. possible role in the deterioration of kidney function [meta-analysis]
      Title: Genome-wide association study of kidney function decline in individuals of European descent.
    2. evidence suggests that CLL patient samples harbor aberrant O-glycosylation highlighted by Tn antigen expression and that the over-expression of GALNT11 constitutes a new molecular marker for CLL
      Title: GALNT11 as a new molecular marker in chronic lymphocytic leukemia.
    3. GALNT11, the human ortholog to Drosophila melanogaster pgant35A, was shown not to support rescue of the l(2)35Aa lethality during Drosophila embryogenesis.
      Title: Rescue of Drosophila Melanogaster l(2)35Aa lethality is only mediated by polypeptide GalNAc-transferase pgant35A, but not by the evolutionary conserved human ortholog GalNAc-transferase-T11.
    4. Single nucleiotide polymorphism in the GALNT11 genes were investigated to assess allele frequencies in different populations. This SNP would be useful marker for forensic individualization, in particular, as ancestry-informative markers.
      Title: A Japanese-specific allele in the GALNT11 gene.
    5. Observational study of genotype prevalence. (HuGE Navigator)
      Title: A Japanese-specific allele in the GALNT11 gene.
    Submit: New GeneRIF Correction

    Phenotypes

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    Find tests for this gene in the NIH Genetic Testing Registry (GTR)

    Review eQTL and phenotype association data in this region using PheGenI

    Variation

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    See variants in ClinVar

    See studies and variants in dbVar

    See Variation Viewer (GRCh37.p13)

    See Variation Viewer (GRCh38)

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Clone Names

    • FLJ21634, MGC71630

    Gene Ontology Provided by GOA

    Function Evidence Code Pubs
    enables Notch binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables Notch binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables carbohydrate binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables polypeptide N-acetylgalactosaminyltransferase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables polypeptide N-acetylgalactosaminyltransferase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables polypeptide N-acetylgalactosaminyltransferase activity TAS
    Traceable Author Statement
    more info
    		  
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in Notch receptor processing ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    involved_in Notch signaling involved in heart development ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    involved_in O-glycan processing TAS
    Traceable Author Statement
    more info
    		  
    involved_in cilium assembly ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    involved_in determination of left/right symmetry ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    involved_in protein O-linked glycosylation IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in protein O-linked glycosylation via threonine IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in regulation of Notch signaling pathway IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in regulation of Notch signaling pathway ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Component Evidence Code Pubs
    is_active_in Golgi apparatus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in Golgi membrane TAS
    Traceable Author Statement
    more info
    		  

    General protein information

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    Preferred Names
    polypeptide N-acetylgalactosaminyltransferase 11
    Names
    UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 11
    UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 11 (GalNAc-T11)
    polypeptide GalNAc transferase 11
    pp-GaNTase 11
    protein-UDP acetylgalactosaminyltransferase 11
    NP_001291443.1
    NP_001358387.1
    NP_001358388.1
    NP_001358389.1
    NP_001358390.1
    NP_001358391.1
    NP_001358392.1
    NP_001358393.1
    NP_001358394.1
    NP_001358395.1
    NP_001358396.1
    NP_001358397.1
    NP_001358398.1
    NP_001358399.1
    NP_001358400.1
    NP_001358401.1
    NP_001358402.1
    NP_001358403.1
    NP_001358404.1
    NP_071370.2
    XP_006716146.1
    XP_006716147.1
    XP_024302625.1
    XP_024302627.1
    XP_024302628.1
    XP_024302629.1
    XP_024302630.1
    XP_047276645.1
    XP_047276646.1
    XP_047276647.1
    XP_054214742.1
    XP_054214743.1
    XP_054214744.1
    XP_054214745.1
    XP_054214746.1
    XP_054214747.1
    XP_054214748.1
    XP_054214749.1
    XP_054214750.1
    XP_054214751.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001304514.2 → NP_001291443.1  polypeptide N-acetylgalactosaminyltransferase 11 isoform 2

      See identical proteins and their annotated locations for NP_001291443.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) lacks part of the 5' coding region and uses an alternate start codon, compared to variant 1. The encoded isoform (2) has a shorter and distinct N-terminus, compared to isoform 1.
      Source sequence(s)
      AC006017
      UniProtKB/TrEMBL
      B7Z5G5
      Conserved Domains (4) summary
      cd02510
      Location:73 → 371
      pp-GalNAc-T; pp-GalNAc-T initiates the formation of mucin-type O-linked glycans
      cd00161
      Location:406 → 525
      RICIN; Ricin-type beta-trefoil; Carbohydrate-binding domain formed from presumed gene triplication. The domain is found in a variety of molecules serving diverse functions such as enzymatic activity, inhibitory toxicity and signal transduction. Highly specific ...
      pfam00652
      Location:402 → 523
      Ricin_B_lectin; Ricin-type beta-trefoil lectin domain
      pfam13641
      Location:73 → 301
      Glyco_tranf_2_3; Glycosyltransferase like family 2

    2. NM_001371458.1 → NP_001358387.1  polypeptide N-acetylgalactosaminyltransferase 11 isoform 1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (3), as well as variants 1 and 4-8, encodes isoform 1.
      Source sequence(s)
      AC006017
      Consensus CDS
      CCDS5930.1
      UniProtKB/Swiss-Prot
      B3KWF4, Q6PCD1, Q8NCW6, Q9H6C2, Q9H6Z5, Q9UDR8
      UniProtKB/TrEMBL
      A0A090N7X6
      Conserved Domains (2) summary
      cd02510
      Location:154 → 452
      pp-GalNAc-T; pp-GalNAc-T initiates the formation of mucin-type O-linked glycans
      pfam00652
      Location:483 → 604
      Ricin_B_lectin; Ricin-type beta-trefoil lectin domain

    3. NM_001371459.1 → NP_001358388.1  polypeptide N-acetylgalactosaminyltransferase 11 isoform 1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (4), as well as variants 1, 3, and 5-8, encodes isoform 1.
      Source sequence(s)
      AC006017
      Consensus CDS
      CCDS5930.1
      UniProtKB/Swiss-Prot
      B3KWF4, Q6PCD1, Q8NCW6, Q9H6C2, Q9H6Z5, Q9UDR8
      UniProtKB/TrEMBL
      A0A090N7X6
      Conserved Domains (2) summary
      cd02510
      Location:154 → 452
      pp-GalNAc-T; pp-GalNAc-T initiates the formation of mucin-type O-linked glycans
      pfam00652
      Location:483 → 604
      Ricin_B_lectin; Ricin-type beta-trefoil lectin domain

    4. NM_001371460.1 → NP_001358389.1  polypeptide N-acetylgalactosaminyltransferase 11 isoform 1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (5), as well as variants 1, 3, 4, and 6-8, encodes isoform 1.
      Source sequence(s)
      AC006017
      Consensus CDS
      CCDS5930.1
      UniProtKB/Swiss-Prot
      B3KWF4, Q6PCD1, Q8NCW6, Q9H6C2, Q9H6Z5, Q9UDR8
      UniProtKB/TrEMBL
      A0A090N7X6
      Conserved Domains (2) summary
      cd02510
      Location:154 → 452
      pp-GalNAc-T; pp-GalNAc-T initiates the formation of mucin-type O-linked glycans
      pfam00652
      Location:483 → 604
      Ricin_B_lectin; Ricin-type beta-trefoil lectin domain

    5. NM_001371461.1 → NP_001358390.1  polypeptide N-acetylgalactosaminyltransferase 11 isoform 1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (6), as well as variants 1, 3-5, 7, and 8, encodes isoform 1.
      Source sequence(s)
      AC006017
      Consensus CDS
      CCDS5930.1
      UniProtKB/Swiss-Prot
      B3KWF4, Q6PCD1, Q8NCW6, Q9H6C2, Q9H6Z5, Q9UDR8
      UniProtKB/TrEMBL
      A0A090N7X6
      Conserved Domains (2) summary
      cd02510
      Location:154 → 452
      pp-GalNAc-T; pp-GalNAc-T initiates the formation of mucin-type O-linked glycans
      pfam00652
      Location:483 → 604
      Ricin_B_lectin; Ricin-type beta-trefoil lectin domain

    6. NM_001371462.1 → NP_001358391.1  polypeptide N-acetylgalactosaminyltransferase 11 isoform 1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (7), as well as variants 1, 3-6, and 8, encodes isoform 1.
      Source sequence(s)
      AC006017
      Consensus CDS
      CCDS5930.1
      UniProtKB/Swiss-Prot
      B3KWF4, Q6PCD1, Q8NCW6, Q9H6C2, Q9H6Z5, Q9UDR8
      UniProtKB/TrEMBL
      A0A090N7X6
      Conserved Domains (2) summary
      cd02510
      Location:154 → 452
      pp-GalNAc-T; pp-GalNAc-T initiates the formation of mucin-type O-linked glycans
      pfam00652
      Location:483 → 604
      Ricin_B_lectin; Ricin-type beta-trefoil lectin domain

    7. NM_001371463.1 → NP_001358392.1  polypeptide N-acetylgalactosaminyltransferase 11 isoform 1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (8), as well as variants 1 and 3-7, encodes isoform 1.
      Source sequence(s)
      AC006017
      Consensus CDS
      CCDS5930.1
      UniProtKB/Swiss-Prot
      B3KWF4, Q6PCD1, Q8NCW6, Q9H6C2, Q9H6Z5, Q9UDR8
      UniProtKB/TrEMBL
      A0A090N7X6
      Conserved Domains (2) summary
      cd02510
      Location:154 → 452
      pp-GalNAc-T; pp-GalNAc-T initiates the formation of mucin-type O-linked glycans
      pfam00652
      Location:483 → 604
      Ricin_B_lectin; Ricin-type beta-trefoil lectin domain

    8. NM_001371464.1 → NP_001358393.1  polypeptide N-acetylgalactosaminyltransferase 11 isoform 3

      Status: VALIDATED

      Description
      Transcript Variant: This variant (9) encodes the longest isoform (3).
      Source sequence(s)
      AC006017
      Conserved Domains (2) summary
      cd02510
      Location:154 → 452
      pp-GalNAc-T; pp-GalNAc-T initiates the formation of mucin-type O-linked glycans
      pfam00652
      Location:483 → 564
      Ricin_B_lectin; Ricin-type beta-trefoil lectin domain

    9. NM_001371465.1 → NP_001358394.1  polypeptide N-acetylgalactosaminyltransferase 11 isoform 4

      Status: VALIDATED

      Description
      Transcript Variant: This variant (10), as well as variants 11 and 12, encodes isoform 4.
      Source sequence(s)
      AC006017
      Conserved Domains (2) summary
      cd02510
      Location:154 → 451
      pp-GalNAc-T; pp-GalNAc-T initiates the formation of mucin-type O-linked glycans
      pfam00652
      Location:482 → 603
      Ricin_B_lectin; Ricin-type beta-trefoil lectin domain

    10. NM_001371466.1 → NP_001358395.1  polypeptide N-acetylgalactosaminyltransferase 11 isoform 4

      Status: VALIDATED

      Description
      Transcript Variant: This variant (11), as well as variants 10 and 12, encodes isoform 4.
      Source sequence(s)
      AC006017
      Conserved Domains (2) summary
      cd02510
      Location:154 → 451
      pp-GalNAc-T; pp-GalNAc-T initiates the formation of mucin-type O-linked glycans
      pfam00652
      Location:482 → 603
      Ricin_B_lectin; Ricin-type beta-trefoil lectin domain

    11. NM_001371467.1 → NP_001358396.1  polypeptide N-acetylgalactosaminyltransferase 11 isoform 4

      Status: VALIDATED

      Description
      Transcript Variant: This variant (12), as well as variants 10 and 11, encodes isoform 4.
      Source sequence(s)
      AC006017
      Conserved Domains (2) summary
      cd02510
      Location:154 → 451
      pp-GalNAc-T; pp-GalNAc-T initiates the formation of mucin-type O-linked glycans
      pfam00652
      Location:482 → 603
      Ricin_B_lectin; Ricin-type beta-trefoil lectin domain

    12. NM_001371468.1 → NP_001358397.1  polypeptide N-acetylgalactosaminyltransferase 11 isoform 5

      Status: VALIDATED

      Description
      Transcript Variant: This variant (13), as well as variants 14 and 15, encodes isoform 5.
      Source sequence(s)
      AC006017
      Conserved Domains (2) summary
      cd02510
      Location:55 → 353
      pp-GalNAc-T; pp-GalNAc-T initiates the formation of mucin-type O-linked glycans
      pfam00652
      Location:384 → 505
      Ricin_B_lectin; Ricin-type beta-trefoil lectin domain

    13. NM_001371469.1 → NP_001358398.1  polypeptide N-acetylgalactosaminyltransferase 11 isoform 5

      Status: VALIDATED

      Description
      Transcript Variant: This variant (14), as well as variants 13 and 15, encodes isoform 5.
      Source sequence(s)
      AC006017
      Conserved Domains (2) summary
      cd02510
      Location:55 → 353
      pp-GalNAc-T; pp-GalNAc-T initiates the formation of mucin-type O-linked glycans
      pfam00652
      Location:384 → 505
      Ricin_B_lectin; Ricin-type beta-trefoil lectin domain

    14. NM_001371470.1 → NP_001358399.1  polypeptide N-acetylgalactosaminyltransferase 11 isoform 5

      Status: VALIDATED

      Description
      Transcript Variant: This variant (15), as well as variants 13 and 14, encodes isoform 5.
      Source sequence(s)
      AC006017
      Conserved Domains (2) summary
      cd02510
      Location:55 → 353
      pp-GalNAc-T; pp-GalNAc-T initiates the formation of mucin-type O-linked glycans
      pfam00652
      Location:384 → 505
      Ricin_B_lectin; Ricin-type beta-trefoil lectin domain

    15. NM_001371471.1 → NP_001358400.1  polypeptide N-acetylgalactosaminyltransferase 11 isoform 6

      Status: VALIDATED

      Description
      Transcript Variant: This variant (16), as well as variant 17, encodes isoform 6.
      Source sequence(s)
      AC006017
      Conserved Domains (1) summary
      cl11394
      Location:154 → 238
      Glyco_tranf_GTA_type; Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold

    16. NM_001371472.1 → NP_001358401.1  polypeptide N-acetylgalactosaminyltransferase 11 isoform 6

      Status: VALIDATED

      Description
      Transcript Variant: This variant (17), as well as variant 16, encodes isoform 6.
      Source sequence(s)
      AC006017
      Conserved Domains (1) summary
      cl11394
      Location:154 → 238
      Glyco_tranf_GTA_type; Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold

    17. NM_001371473.1 → NP_001358402.1  polypeptide N-acetylgalactosaminyltransferase 11 isoform 7

      Status: VALIDATED

      Description
      Transcript Variant: This variant (18), as well as variant 19, encodes isoform 7.
      Source sequence(s)
      AC006017
      Consensus CDS
      CCDS94237.1
      UniProtKB/TrEMBL
      C9J8A7
      Related
      ENSP00000397581.1, ENST00000419245.5
      Conserved Domains (1) summary
      cl11394
      Location:154 → 195
      Glyco_tranf_GTA_type; Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold

    18. NM_001371474.1 → NP_001358403.1  polypeptide N-acetylgalactosaminyltransferase 11 isoform 7

      Status: VALIDATED

      Description
      Transcript Variant: This variant (19), as well as variant 18, encodes isoform 7.
      Source sequence(s)
      AC006017, BC059377
      Consensus CDS
      CCDS94237.1
      UniProtKB/TrEMBL
      C9J8A7
      Related
      ENSP00000410093.1, ENST00000415421.5
      Conserved Domains (1) summary
      cl11394
      Location:154 → 195
      Glyco_tranf_GTA_type; Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold

    19. NM_001371475.1 → NP_001358404.1  polypeptide N-acetylgalactosaminyltransferase 11 isoform 8

      Status: VALIDATED

      Source sequence(s)
      AC006017
      Conserved Domains (2) summary
      cd02510
      Location:154 → 410
      pp-GalNAc-T; pp-GalNAc-T initiates the formation of mucin-type O-linked glycans
      pfam00652
      Location:441 → 562
      Ricin_B_lectin; Ricin-type beta-trefoil lectin domain

    20. NM_022087.4 → NP_071370.2  polypeptide N-acetylgalactosaminyltransferase 11 isoform 1

      See identical proteins and their annotated locations for NP_071370.2

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1), as well as variants 3-8, encodes isoform 1.
      Source sequence(s)
      AC006017
      Consensus CDS
      CCDS5930.1
      UniProtKB/Swiss-Prot
      B3KWF4, Q6PCD1, Q8NCW6, Q9H6C2, Q9H6Z5, Q9UDR8
      UniProtKB/TrEMBL
      A0A090N7X6
      Related
      ENSP00000395122.2, ENST00000430044.7
      Conserved Domains (2) summary
      cd02510
      Location:154 → 452
      pp-GalNAc-T; pp-GalNAc-T initiates the formation of mucin-type O-linked glycans
      pfam00652
      Location:483 → 604
      Ricin_B_lectin; Ricin-type beta-trefoil lectin domain

    RNA

    1. NR_163956.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC006017

    2. NR_163957.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC006017

    3. NR_163958.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC006017

    4. NR_163959.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC006017

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000007.14 Reference GRCh38.p14 Primary Assembly

      Range
      152025674..152122340
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_047420691.1 → XP_047276647.1  polypeptide N-acetylgalactosaminyltransferase 11 isoform X1

      UniProtKB/Swiss-Prot
      B3KWF4, Q6PCD1, Q8NCW6, Q9H6C2, Q9H6Z5, Q9UDR8
      UniProtKB/TrEMBL
      A0A090N7X6

    2. XM_024446857.2 → XP_024302625.1  polypeptide N-acetylgalactosaminyltransferase 11 isoform X1

      UniProtKB/Swiss-Prot
      B3KWF4, Q6PCD1, Q8NCW6, Q9H6C2, Q9H6Z5, Q9UDR8
      UniProtKB/TrEMBL
      A0A090N7X6
      Related
      ENSP00000416787.1, ENST00000434507.5
      Conserved Domains (2) summary
      cd02510
      Location:154 → 452
      pp-GalNAc-T; pp-GalNAc-T initiates the formation of mucin-type O-linked glycans
      pfam00652
      Location:483 → 604
      Ricin_B_lectin; Ricin-type beta-trefoil lectin domain

    3. XM_024446859.2 → XP_024302627.1  polypeptide N-acetylgalactosaminyltransferase 11 isoform X1

      UniProtKB/Swiss-Prot
      B3KWF4, Q6PCD1, Q8NCW6, Q9H6C2, Q9H6Z5, Q9UDR8
      UniProtKB/TrEMBL
      A0A090N7X6
      Conserved Domains (2) summary
      cd02510
      Location:154 → 452
      pp-GalNAc-T; pp-GalNAc-T initiates the formation of mucin-type O-linked glycans
      pfam00652
      Location:483 → 604
      Ricin_B_lectin; Ricin-type beta-trefoil lectin domain

    4. XM_047420690.1 → XP_047276646.1  polypeptide N-acetylgalactosaminyltransferase 11 isoform X1

      UniProtKB/Swiss-Prot
      B3KWF4, Q6PCD1, Q8NCW6, Q9H6C2, Q9H6Z5, Q9UDR8
      UniProtKB/TrEMBL
      A0A090N7X6

    5. XM_047420689.1 → XP_047276645.1  polypeptide N-acetylgalactosaminyltransferase 11 isoform X1

      UniProtKB/Swiss-Prot
      B3KWF4, Q6PCD1, Q8NCW6, Q9H6C2, Q9H6Z5, Q9UDR8
      UniProtKB/TrEMBL
      A0A090N7X6

    6. XM_024446860.2 → XP_024302628.1  polypeptide N-acetylgalactosaminyltransferase 11 isoform X1

      UniProtKB/Swiss-Prot
      B3KWF4, Q6PCD1, Q8NCW6, Q9H6C2, Q9H6Z5, Q9UDR8
      UniProtKB/TrEMBL
      A0A090N7X6
      Conserved Domains (2) summary
      cd02510
      Location:154 → 452
      pp-GalNAc-T; pp-GalNAc-T initiates the formation of mucin-type O-linked glycans
      pfam00652
      Location:483 → 604
      Ricin_B_lectin; Ricin-type beta-trefoil lectin domain

    7. XM_024446861.2 → XP_024302629.1  polypeptide N-acetylgalactosaminyltransferase 11 isoform X1

      UniProtKB/Swiss-Prot
      B3KWF4, Q6PCD1, Q8NCW6, Q9H6C2, Q9H6Z5, Q9UDR8
      UniProtKB/TrEMBL
      A0A090N7X6
      Conserved Domains (2) summary
      cd02510
      Location:154 → 452
      pp-GalNAc-T; pp-GalNAc-T initiates the formation of mucin-type O-linked glycans
      pfam00652
      Location:483 → 604
      Ricin_B_lectin; Ricin-type beta-trefoil lectin domain

    8. XM_006716084.3 → XP_006716147.1  polypeptide N-acetylgalactosaminyltransferase 11 isoform X1

      See identical proteins and their annotated locations for XP_006716147.1

      UniProtKB/Swiss-Prot
      B3KWF4, Q6PCD1, Q8NCW6, Q9H6C2, Q9H6Z5, Q9UDR8
      UniProtKB/TrEMBL
      A0A090N7X6
      Conserved Domains (2) summary
      cd02510
      Location:154 → 452
      pp-GalNAc-T; pp-GalNAc-T initiates the formation of mucin-type O-linked glycans
      pfam00652
      Location:483 → 604
      Ricin_B_lectin; Ricin-type beta-trefoil lectin domain

    9. XM_024446862.2 → XP_024302630.1  polypeptide N-acetylgalactosaminyltransferase 11 isoform X1

      UniProtKB/Swiss-Prot
      B3KWF4, Q6PCD1, Q8NCW6, Q9H6C2, Q9H6Z5, Q9UDR8
      UniProtKB/TrEMBL
      A0A090N7X6
      Conserved Domains (2) summary
      cd02510
      Location:154 → 452
      pp-GalNAc-T; pp-GalNAc-T initiates the formation of mucin-type O-linked glycans
      pfam00652
      Location:483 → 604
      Ricin_B_lectin; Ricin-type beta-trefoil lectin domain

    10. XM_006716083.3 → XP_006716146.1  polypeptide N-acetylgalactosaminyltransferase 11 isoform X1

      See identical proteins and their annotated locations for XP_006716146.1

      UniProtKB/Swiss-Prot
      B3KWF4, Q6PCD1, Q8NCW6, Q9H6C2, Q9H6Z5, Q9UDR8
      UniProtKB/TrEMBL
      A0A090N7X6
      Conserved Domains (2) summary
      cd02510
      Location:154 → 452
      pp-GalNAc-T; pp-GalNAc-T initiates the formation of mucin-type O-linked glycans
      pfam00652
      Location:483 → 604
      Ricin_B_lectin; Ricin-type beta-trefoil lectin domain

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060931.1 Alternate T2T-CHM13v2.0

      Range
      153198601..153295227
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_054358770.1 → XP_054214745.1  polypeptide N-acetylgalactosaminyltransferase 11 isoform X1

      UniProtKB/Swiss-Prot
      B3KWF4, Q6PCD1, Q8NCW6, Q9H6C2, Q9H6Z5, Q9UDR8
      UniProtKB/TrEMBL
      A0A090N7X6

    2. XM_054358767.1 → XP_054214742.1  polypeptide N-acetylgalactosaminyltransferase 11 isoform X1

      UniProtKB/Swiss-Prot
      B3KWF4, Q6PCD1, Q8NCW6, Q9H6C2, Q9H6Z5, Q9UDR8
      UniProtKB/TrEMBL
      A0A090N7X6

    3. XM_054358771.1 → XP_054214746.1  polypeptide N-acetylgalactosaminyltransferase 11 isoform X1

      UniProtKB/Swiss-Prot
      B3KWF4, Q6PCD1, Q8NCW6, Q9H6C2, Q9H6Z5, Q9UDR8
      UniProtKB/TrEMBL
      A0A090N7X6

    4. XM_054358769.1 → XP_054214744.1  polypeptide N-acetylgalactosaminyltransferase 11 isoform X1

      UniProtKB/Swiss-Prot
      B3KWF4, Q6PCD1, Q8NCW6, Q9H6C2, Q9H6Z5, Q9UDR8
      UniProtKB/TrEMBL
      A0A090N7X6

    5. XM_054358768.1 → XP_054214743.1  polypeptide N-acetylgalactosaminyltransferase 11 isoform X1

      UniProtKB/Swiss-Prot
      B3KWF4, Q6PCD1, Q8NCW6, Q9H6C2, Q9H6Z5, Q9UDR8
      UniProtKB/TrEMBL
      A0A090N7X6

    6. XM_054358774.1 → XP_054214749.1  polypeptide N-acetylgalactosaminyltransferase 11 isoform X1

      UniProtKB/Swiss-Prot
      B3KWF4, Q6PCD1, Q8NCW6, Q9H6C2, Q9H6Z5, Q9UDR8
      UniProtKB/TrEMBL
      A0A090N7X6

    7. XM_054358772.1 → XP_054214747.1  polypeptide N-acetylgalactosaminyltransferase 11 isoform X1

      UniProtKB/Swiss-Prot
      B3KWF4, Q6PCD1, Q8NCW6, Q9H6C2, Q9H6Z5, Q9UDR8
      UniProtKB/TrEMBL
      A0A090N7X6

    8. XM_054358775.1 → XP_054214750.1  polypeptide N-acetylgalactosaminyltransferase 11 isoform X1

      UniProtKB/Swiss-Prot
      B3KWF4, Q6PCD1, Q8NCW6, Q9H6C2, Q9H6Z5, Q9UDR8
      UniProtKB/TrEMBL
      A0A090N7X6

    9. XM_054358773.1 → XP_054214748.1  polypeptide N-acetylgalactosaminyltransferase 11 isoform X1

      UniProtKB/Swiss-Prot
      B3KWF4, Q6PCD1, Q8NCW6, Q9H6C2, Q9H6Z5, Q9UDR8
      UniProtKB/TrEMBL
      A0A090N7X6

    10. XM_054358776.1 → XP_054214751.1  polypeptide N-acetylgalactosaminyltransferase 11 isoform X1

      UniProtKB/Swiss-Prot
      B3KWF4, Q6PCD1, Q8NCW6, Q9H6C2, Q9H6Z5, Q9UDR8
      UniProtKB/TrEMBL
      A0A090N7X6
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8NCW6.2 GenPept UniProtKB/Swiss-Prot:Q8NCW6

    Gene LinkOut

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