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    RABL2A RAB, member of RAS oncogene family like 2A [ Homo sapiens (human) ]

    Gene ID: 11159, updated on 10-Dec-2024

    Summary

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    Official Symbol
    RABL2Aprovided by HGNC
    Official Full Name
    RAB, member of RAS oncogene family like 2Aprovided by HGNC
    Primary source
    HGNC:HGNC:9799
    See related
    Ensembl:ENSG00000144134 MIM:605412; AllianceGenome:HGNC:9799
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Summary
    This gene is a member of the RAB gene family which belongs to the RAS GTPase superfamily. The proteins in the family of RAS-related signaling molecules are small GTP-binding proteins that play important roles in the regulation of exocytotic and endocytotic pathways. This gene maps to the site of an ancestral telomere fusion event and may be a subtelomeric gene. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Apr 2015]
    Expression
    Ubiquitous expression in testis (RPKM 5.1), lung (RPKM 4.1) and 25 other tissues See more
    Orthologs
    all
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    Genomic context

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    See RABL2A in Genome Data Viewer
    Location:
    2q14.1
    Exon count:
    12
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 2 NC_000002.12 (113627266..113643392)
    RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 2 NC_060926.1 (114051994..114068120)
    RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 2 NC_000002.11 (114384843..114400969)

    Chromosome 2 - NC_000002.12Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC124907874 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 11884 Neighboring gene DEAD/H-box helicase 11 like 2 (pseudogene) Neighboring gene ribosomal protein L23a pseudogene 7 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 11885 Neighboring gene uncharacterized LOC112268423 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr2:114413451-114414008 Neighboring gene SNRPA1 pseudogene 1 Neighboring gene ACR pseudogene 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: HPA RNA-seq normal tissues
    • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
    • BioProject: PRJEB4337
    • Publication: PMID 24309898
    • Analysis date: Wed Apr 4 07:08:55 2018

    Bibliography

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    Related articles in PubMed

    1. Genetic variants in the RABL2A gene in fertile and oligoasthenospermic infertile men. Jamsai D, et al. Fertil Steril, 2014 Jul. PMID 24825419
    2. Architecture of RabL2-associated complexes at the ciliary base: A structural modeling perspective: Deciphering the structural organization of ciliary RabL2 complexes. Boegholm N, et al. Bioessays, 2024 Sep. PMID 38991980
    3. RABL2A-CCDC34 Axis Promotes Sorafenib Resistance in Hepatocellular Carcinoma. Zhou M, et al. DNA Cell Biol, 2021 Nov. PMID 34767735
    4. RABL2 positively controls localization of GPCRs in mammalian primary cilia. Dateyama I, et al. J Cell Sci, 2019 Jan 16. PMID 30578315
    5. Variants in RABL2A causing male infertility and ciliopathy. Ding X, et al. Hum Mol Genet, 2020 Dec 18. PMID 33075816, Free PMC Article

    See all (25) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Architecture of RabL2-associated complexes at the ciliary base: A structural modeling perspective: Deciphering the structural organization of ciliary RabL2 complexes.
      Title: Architecture of RabL2-associated complexes at the ciliary base: A structural modeling perspective: Deciphering the structural organization of ciliary RabL2 complexes.
    2. RABL2A-CCDC34 Axis Promotes Sorafenib Resistance in Hepatocellular Carcinoma.
      Title: RABL2A-CCDC34 Axis Promotes Sorafenib Resistance in Hepatocellular Carcinoma.
    3. Variants in RABL2A causing male infertility and ciliopathy.
      Title: Variants in RABL2A causing male infertility and ciliopathy.
    4. RABL2 controls localization of GPR161 independently of TULP3, which promotes entry of ciliary GPCRs.
      Title: RABL2 positively controls localization of GPCRs in mammalian primary cilia.
    5. Suggest the 114391996 delC allele in the RABL2A gene may act as a risk factor for oligoasthenospermic infertility in Australian men.
      Title: Genetic variants in the RABL2A gene in fertile and oligoasthenospermic infertile men.
    6. In human samples no deviations of the euploid genomic state could be detected indicating that 22q13 microdeletions involving RABL2B are rare.
      Title: Analysis of relative gene dosage and expression differences of the paralogs RABL2A and RABL2B by Pyrosequencing.
    Submit: New GeneRIF Correction

    Phenotypes

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    Review eQTL and phenotype association data in this region using PheGenI

    Copy number response

    Description
    Copy number response
    Triplosensitivity

    No evidence available (Last evaluated 2021-02-02)

    ClinGen Genome Curation Page
    Haploinsufficency

    Dosage sensitivity unlikely (Last evaluated 2021-02-02)

    ClinGen Genome Curation PagePubMed

    Variation

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    See variants in ClinVar

    See studies and variants in dbVar

    See Variation Viewer (GRCh37.p13)

    See Variation Viewer (GRCh38)

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Clone Names

    • FLJ78724, MGC117180

    Gene Ontology Provided by GOA

    Function Evidence Code Pubs
    enables GTP binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables GTPase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in intracellular protein transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in endomembrane system IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    rab-like protein 2A

    NCBI Reference Sequences (RefSeq)

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    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001306158.2 → NP_001293087.1  rab-like protein 2A isoform 2

      See identical proteins and their annotated locations for NP_001293087.1

      Status: REVIEWED

      Description
      Transcript Variant: This variant (3) encodes isoform 3. Variants 3, 4, and 13-15 all encode the same isoform (2).
      Source sequence(s)
      AK092971, BI552699, CA427898, CR456554, HY023006, HY075940
      Consensus CDS
      CCDS77454.1
      UniProtKB/TrEMBL
      Q6IC14
      Related
      ENSP00000507832.1, ENST00000683472.1
      Conserved Domains (1) summary
      cd04124
      Location:22 → 182
      RabL2; Rab GTPase-like family 2 (Rab-like2)

    2. NM_001306159.2 → NP_001293088.1  rab-like protein 2A isoform 2

      See identical proteins and their annotated locations for NP_001293088.1

      Status: REVIEWED

      Description
      Transcript Variant: This variant (4) differs in the 3' UTR compared to variant 3. Variants 3, 4, and 13-15 all encode the same isoform (2).
      Source sequence(s)
      BC144052, BI552699, CA427898, CR456554, HY023006, HY075940
      Consensus CDS
      CCDS77454.1
      UniProtKB/TrEMBL
      Q6IC14
      Related
      ENSP00000376870.3, ENST00000393165.7
      Conserved Domains (1) summary
      cd04124
      Location:22 → 182
      RabL2; Rab GTPase-like family 2 (Rab-like2)

    3. NM_001306160.3 → NP_001293089.1  rab-like protein 2A isoform 3

      Status: REVIEWED

      Description
      Transcript Variant: This variant (5) differs in the 5' and 3' UTRs and uses two alternate in-frame splice sites in the central coding region, compared to variant 3. The encoded isoform (3) is longer than isoform 2. Variants 5 and 12 both encode the same isoform (3).
      Source sequence(s)
      AL078621
      Consensus CDS
      CCDS77455.1
      UniProtKB/Swiss-Prot
      Q9UBK7
      Conserved Domains (1) summary
      cd04124
      Location:22 → 191
      RabL2; Rab GTPase-like family 2 (Rab-like2)

    4. NM_001306161.2 → NP_001293090.1  rab-like protein 2A isoform 4

      See identical proteins and their annotated locations for NP_001293090.1

      Status: REVIEWED

      Description
      Transcript Variant: This variant (6) lacks two consecutive alternate in-frame exons in the central coding region compared to variant 3. The encoded isoform (4) is shorter than isoform 2. Variants 6, 20, and 21 all encode the same isoform (4).
      Source sequence(s)
      AK092971, BC111008, BI552699, CA427898, CR456554, DB451301, HY023006
      Consensus CDS
      CCDS77456.1
      UniProtKB/TrEMBL
      A8MXF6, B7ZBD5, Q2TAB6
      Related
      ENSP00000386460.1, ENST00000409842.5
      Conserved Domains (1) summary
      cl21455
      Location:22 → 118
      P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases

    5. NM_001354405.2 → NP_001341334.1  rab-like protein 2A isoform 5

      Status: REVIEWED

      Description
      Transcript Variant: This variant (7), as well as variants 8-11, encodes the longest isoform (5).
      Source sequence(s)
      AL078621
      Conserved Domains (1) summary
      cd04124
      Location:22 → 192
      RabL2; Rab GTPase-like family 2 (Rab-like2)

    6. NM_001354406.2 → NP_001341335.1  rab-like protein 2A isoform 5

      Status: REVIEWED

      Description
      Transcript Variant: This variant (8), as well as variants 7 and 9-11, encodes the longest isoform (5).
      Source sequence(s)
      AL078621
      Conserved Domains (1) summary
      cd04124
      Location:22 → 192
      RabL2; Rab GTPase-like family 2 (Rab-like2)

    7. NM_001354407.2 → NP_001341336.1  rab-like protein 2A isoform 5

      Status: REVIEWED

      Description
      Transcript Variant: This variant (9), as well as variants 7, 8, 10, and 11, encodes the longest isoform (5).
      Source sequence(s)
      AL078621
      Conserved Domains (1) summary
      cd04124
      Location:22 → 192
      RabL2; Rab GTPase-like family 2 (Rab-like2)

    8. NM_001354408.2 → NP_001341337.1  rab-like protein 2A isoform 5

      Status: REVIEWED

      Description
      Transcript Variant: This variant (10), as well as variants 7-9 and 11, encodes the longest isoform (5).
      Source sequence(s)
      AL078621
      Conserved Domains (1) summary
      cd04124
      Location:22 → 192
      RabL2; Rab GTPase-like family 2 (Rab-like2)

    9. NM_001354409.2 → NP_001341338.1  rab-like protein 2A isoform 5

      Status: REVIEWED

      Description
      Transcript Variant: This variant (11), as well as variants 7-10, encodes the longest isoform (5).
      Source sequence(s)
      AL078621
      Conserved Domains (1) summary
      cd04124
      Location:22 → 192
      RabL2; Rab GTPase-like family 2 (Rab-like2)

    10. NM_001354410.2 → NP_001341339.1  rab-like protein 2A isoform 3

      Status: REVIEWED

      Description
      Transcript Variant: This variant (12), as well as variant 5, encodes isoform 3.
      Source sequence(s)
      AL078621
      Consensus CDS
      CCDS77455.1
      Related
      ENSP00000387229.1, ENST00000409875.5
      Conserved Domains (1) summary
      cd04124
      Location:22 → 191
      RabL2; Rab GTPase-like family 2 (Rab-like2)

    11. NM_001354412.2 → NP_001341341.1  rab-like protein 2A isoform 2

      Status: REVIEWED

      Description
      Transcript Variant: This variant (13), as well as variants 3, 4, 14, and 15, encodes isoform 2.
      Source sequence(s)
      AL078621
      Consensus CDS
      CCDS77454.1
      UniProtKB/TrEMBL
      Q6IC14
      Related
      ENST00000409121.6
      Conserved Domains (1) summary
      cd04124
      Location:22 → 182
      RabL2; Rab GTPase-like family 2 (Rab-like2)

    12. NM_001354413.2 → NP_001341342.1  rab-like protein 2A isoform 2

      Status: REVIEWED

      Description
      Transcript Variant: This variant (14), as well as variants 3, 4, 13, and 15, encodes isoform 2.
      Source sequence(s)
      AL078621
      Consensus CDS
      CCDS77454.1
      UniProtKB/TrEMBL
      Q6IC14
      Conserved Domains (1) summary
      cd04124
      Location:22 → 182
      RabL2; Rab GTPase-like family 2 (Rab-like2)

    13. NM_001354414.2 → NP_001341343.1  rab-like protein 2A isoform 2

      Status: REVIEWED

      Description
      Transcript Variant: This variant (15), as well as variants 3, 4, 13, and 14, encodes isoform 2.
      Source sequence(s)
      AL078621
      Consensus CDS
      CCDS77454.1
      UniProtKB/TrEMBL
      Q6IC14
      Conserved Domains (1) summary
      cd04124
      Location:22 → 182
      RabL2; Rab GTPase-like family 2 (Rab-like2)

    14. NM_001354416.2 → NP_001341345.1  rab-like protein 2A isoform 1

      Status: REVIEWED

      Description
      Transcript Variant: This variant (16), as well as variants 1 and 2, encodes isoform 1.
      Source sequence(s)
      AL078621
      Consensus CDS
      CCDS2118.1
      UniProtKB/Swiss-Prot
      B7ZBD6, Q9NU37, Q9UBK7
      Conserved Domains (1) summary
      cd04124
      Location:22 → 181
      RabL2; Rab GTPase-like family 2 (Rab-like2)

    15. NM_001354417.2 → NP_001341346.1  rab-like protein 2A isoform 6

      Status: REVIEWED

      Source sequence(s)
      AL078621, BC144050
      UniProtKB/TrEMBL
      A0AUY0
      Conserved Domains (1) summary
      cd04124
      Location:22 → 182
      RabL2; Rab GTPase-like family 2 (Rab-like2)

    16. NM_001354418.2 → NP_001341347.1  rab-like protein 2A isoform 7

      Status: REVIEWED

      Description
      Transcript Variant: This variant (18), as well as variant 19, encodes isoform 7.
      Source sequence(s)
      AL078621
      UniProtKB/TrEMBL
      A8MXF6, Q2TAB6
      Conserved Domains (1) summary
      cl21455
      Location:22 → 128
      P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases

    17. NM_001354419.2 → NP_001341348.1  rab-like protein 2A isoform 7

      Status: REVIEWED

      Description
      Transcript Variant: This variant (19), as well as variant 18, encodes isoform 7.
      Source sequence(s)
      AL078621
      UniProtKB/TrEMBL
      A8MXF6, Q2TAB6
      Conserved Domains (1) summary
      cl21455
      Location:22 → 128
      P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases

    18. NM_001354421.2 → NP_001341350.1  rab-like protein 2A isoform 4

      Status: REVIEWED

      Description
      Transcript Variant: This variant (20), as well as variants 6 and 21, encodes isoform 4.
      Source sequence(s)
      AL078621
      Consensus CDS
      CCDS77456.1
      UniProtKB/TrEMBL
      A8MXF6, B7ZBD5, Q2TAB6
      Conserved Domains (1) summary
      cl21455
      Location:22 → 118
      P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases

    19. NM_001354423.2 → NP_001341352.1  rab-like protein 2A isoform 4

      Status: REVIEWED

      Description
      Transcript Variant: This variant (21), as well as variants 6 and 20, encodes isoform 4.
      Source sequence(s)
      AL078621
      Consensus CDS
      CCDS77456.1
      UniProtKB/TrEMBL
      A8MXF6, B7ZBD5, Q2TAB6
      Conserved Domains (1) summary
      cl21455
      Location:22 → 118
      P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases

    20. NM_001354424.2 → NP_001341353.1  rab-like protein 2A isoform 8

      Status: REVIEWED

      Source sequence(s)
      AL078621
      UniProtKB/TrEMBL
      A8MXF6, Q2TAB6
      Conserved Domains (1) summary
      cl21455
      Location:22 → 117
      P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases

    21. NM_001354425.2 → NP_001341354.1  rab-like protein 2A isoform 9

      Status: REVIEWED

      Source sequence(s)
      AL078621
      Conserved Domains (1) summary
      cl21455
      Location:1 → 107
      P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases

    22. NM_001354426.2 → NP_001341355.1  rab-like protein 2A isoform 10

      Status: REVIEWED

      Source sequence(s)
      AL078621
      Conserved Domains (1) summary
      cl21455
      Location:1 → 97
      P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases

    23. NM_001354427.2 → NP_001341356.1  rab-like protein 2A isoform 11

      Status: REVIEWED

      Source sequence(s)
      AL078621
      Conserved Domains (1) summary
      cl21455
      Location:2 → 90
      P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases

    24. NM_001354428.2 → NP_001341357.1  rab-like protein 2A isoform 12

      Status: REVIEWED

      Source sequence(s)
      AL078621
      Conserved Domains (1) summary
      cl21455
      Location:2 → 89
      P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases

    25. NM_007082.5 → NP_009013.1  rab-like protein 2A isoform 1

      See identical proteins and their annotated locations for NP_009013.1

      Status: REVIEWED

      Description
      Transcript Variant: This variant (2) differs in the 3' UTR and uses an alternate in-frame splice site in the central coding region, compared to variant 3. The encoded isoform (1) is one amino acid shorter than isoform 2. Variants 1, 2, and 16 all encode the same isoform (1).
      Source sequence(s)
      AF095350, BI552699, BU728800, HY023006
      Consensus CDS
      CCDS2118.1
      UniProtKB/Swiss-Prot
      B7ZBD6, Q9NU37, Q9UBK7
      Related
      ENSP00000376871.3, ENST00000393166.7
      Conserved Domains (1) summary
      cd04124
      Location:22 → 181
      RabL2; Rab GTPase-like family 2 (Rab-like2)

    26. NM_013412.4 → NP_038198.1  rab-like protein 2A isoform 1

      See identical proteins and their annotated locations for NP_038198.1

      Status: REVIEWED

      Description
      Transcript Variant: This variant (1) uses an alternate in-frame splice site in the central coding region, compared to variant 3. The encoded isoform (1) is one amino acid shorter than isoform 2. Variants 1, 2, and 16 all encode the same isoform (1).
      Source sequence(s)
      AF095351, AK092971, BI552699, CA427898, HY023006
      Consensus CDS
      CCDS2118.1
      UniProtKB/Swiss-Prot
      B7ZBD6, Q9NU37, Q9UBK7
      Related
      ENSP00000376872.3, ENST00000393167.7
      Conserved Domains (1) summary
      cd04124
      Location:22 → 181
      RabL2; Rab GTPase-like family 2 (Rab-like2)

    RNA

    1. NR_148879.2 RNA Sequence

      Status: REVIEWED

      Source sequence(s)
      AL078621

    2. NR_148880.2 RNA Sequence

      Status: REVIEWED

      Source sequence(s)
      AL078621

    3. NR_148881.2 RNA Sequence

      Status: REVIEWED

      Source sequence(s)
      AL078621
      Related
      ENST00000450954.5

    4. NR_148882.2 RNA Sequence

      Status: REVIEWED

      Source sequence(s)
      AL078621
      Related
      ENST00000452831.5

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000002.12 Reference GRCh38.p14 Primary Assembly

      Range
      113627266..113643392
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_017003207.2 → XP_016858696.1  rab-like protein 2A isoform X1

      Conserved Domains (1) summary
      cd04124
      Location:22 → 192
      RabL2; Rab GTPase-like family 2 (Rab-like2)

    2. XM_047443039.1 → XP_047298995.1  rab-like protein 2A isoform X1

    3. XM_017003205.2 → XP_016858694.1  rab-like protein 2A isoform X1

      Conserved Domains (1) summary
      cd04124
      Location:22 → 192
      RabL2; Rab GTPase-like family 2 (Rab-like2)

    4. XM_047443045.1 → XP_047299001.1  rab-like protein 2A isoform X5

      UniProtKB/TrEMBL
      Q6IC14

    5. XM_017003215.2 → XP_016858704.1  rab-like protein 2A isoform X5

      UniProtKB/TrEMBL
      Q6IC14
      Conserved Domains (1) summary
      cd04124
      Location:22 → 182
      RabL2; Rab GTPase-like family 2 (Rab-like2)

    6. XM_024452573.2 → XP_024308341.1  rab-like protein 2A isoform X2

      Conserved Domains (1) summary
      cd04124
      Location:22 → 191
      RabL2; Rab GTPase-like family 2 (Rab-like2)

    7. XM_017003220.2 → XP_016858709.1  rab-like protein 2A isoform X6

      UniProtKB/Swiss-Prot
      B7ZBD6, Q9NU37, Q9UBK7
      Conserved Domains (1) summary
      cd04124
      Location:22 → 181
      RabL2; Rab GTPase-like family 2 (Rab-like2)

    8. XM_047443050.1 → XP_047299006.1  rab-like protein 2A isoform X6

      UniProtKB/Swiss-Prot
      B7ZBD6, Q9NU37, Q9UBK7

    9. XM_047443053.1 → XP_047299009.1  rab-like protein 2A isoform X8

      UniProtKB/TrEMBL
      A8MXF6, B7ZBD5, Q2TAB6

    10. XM_047443055.1 → XP_047299011.1  rab-like protein 2A isoform X8

      UniProtKB/TrEMBL
      A8MXF6, B7ZBD5, Q2TAB6
      Related
      ENSP00000365622.3, ENST00000376439.3

    11. XM_047443047.1 → XP_047299003.1  rab-like protein 2A isoform X5

      UniProtKB/TrEMBL
      Q6IC14

    12. XM_047443049.1 → XP_047299005.1  rab-like protein 2A isoform X6

      UniProtKB/Swiss-Prot
      B7ZBD6, Q9NU37, Q9UBK7

    13. XM_047443054.1 → XP_047299010.1  rab-like protein 2A isoform X8

      UniProtKB/TrEMBL
      A8MXF6, B7ZBD5, Q2TAB6

    14. XM_047443044.1 → XP_047299000.1  rab-like protein 2A isoform X3

    15. XM_047443056.1 → XP_047299012.1  rab-like protein 2A isoform X8

      UniProtKB/TrEMBL
      A8MXF6, B7ZBD5, Q2TAB6

    16. XM_047443041.1 → XP_047298997.1  rab-like protein 2A isoform X1

    17. XM_024452575.2 → XP_024308343.1  rab-like protein 2A isoform X5

      UniProtKB/TrEMBL
      Q6IC14
      Conserved Domains (1) summary
      cd04124
      Location:22 → 182
      RabL2; Rab GTPase-like family 2 (Rab-like2)

    18. XM_017003210.2 → XP_016858699.1  rab-like protein 2A isoform X3

      Conserved Domains (2) summary
      cd04124
      Location:22 → 188
      RabL2; Rab GTPase-like family 2 (Rab-like2)
      smart00175
      Location:22 → 167
      RAB; Rab subfamily of small GTPases

    19. XM_047443048.1 → XP_047299004.1  rab-like protein 2A isoform X5

      UniProtKB/TrEMBL
      Q6IC14

    20. XM_017003212.2 → XP_016858701.1  rab-like protein 2A isoform X4

    21. XM_047443051.1 → XP_047299007.1  rab-like protein 2A isoform X6

      UniProtKB/Swiss-Prot
      B7ZBD6, Q9NU37, Q9UBK7

    22. XM_047443057.1 → XP_047299013.1  rab-like protein 2A isoform X9

      UniProtKB/TrEMBL
      A8MXF6, Q2TAB6

    23. XM_017003211.2 → XP_016858700.1  rab-like protein 2A isoform X3

      Conserved Domains (2) summary
      cd04124
      Location:22 → 188
      RabL2; Rab GTPase-like family 2 (Rab-like2)
      smart00175
      Location:22 → 167
      RAB; Rab subfamily of small GTPases

    24. XM_047443043.1 → XP_047298999.1  rab-like protein 2A isoform X2

    25. XM_047443052.1 → XP_047299008.1  rab-like protein 2A isoform X7

      UniProtKB/TrEMBL
      A8MXF6, Q2TAB6

    26. XM_047443063.1 → XP_047299019.1  rab-like protein 2A isoform X13

    27. XM_047443062.1 → XP_047299018.1  rab-like protein 2A isoform X13

    28. XM_011510509.2 → XP_011508811.1  rab-like protein 2A isoform X1

      See identical proteins and their annotated locations for XP_011508811.1

      Conserved Domains (1) summary
      cd04124
      Location:22 → 192
      RabL2; Rab GTPase-like family 2 (Rab-like2)

    29. XM_047443059.1 → XP_047299015.1  rab-like protein 2A isoform X11

    30. XM_047443061.1 → XP_047299017.1  rab-like protein 2A isoform X12

    31. XM_047443060.1 → XP_047299016.1  rab-like protein 2A isoform X11

    32. XM_047443058.1 → XP_047299014.1  rab-like protein 2A isoform X10

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060926.1 Alternate T2T-CHM13v2.0

      Range
      114051994..114068120
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_054340260.1 → XP_054196235.1  rab-like protein 2A isoform X1

    2. XM_054340263.1 → XP_054196238.1  rab-like protein 2A isoform X1

    3. XM_054340271.1 → XP_054196246.1  rab-like protein 2A isoform X5

      UniProtKB/TrEMBL
      Q6IC14

    4. XM_054340272.1 → XP_054196247.1  rab-like protein 2A isoform X5

      UniProtKB/TrEMBL
      Q6IC14

    5. XM_054340265.1 → XP_054196240.1  rab-like protein 2A isoform X2

    6. XM_054340276.1 → XP_054196251.1  rab-like protein 2A isoform X6

      UniProtKB/Swiss-Prot
      B7ZBD6, Q9NU37, Q9UBK7

    7. XM_054340278.1 → XP_054196253.1  rab-like protein 2A isoform X6

      UniProtKB/Swiss-Prot
      B7ZBD6, Q9NU37, Q9UBK7

    8. XM_054340281.1 → XP_054196256.1  rab-like protein 2A isoform X8

      UniProtKB/TrEMBL
      A8MXF6, B7ZBD5, Q2TAB6

    9. XM_054340283.1 → XP_054196258.1  rab-like protein 2A isoform X8

      UniProtKB/TrEMBL
      A8MXF6, B7ZBD5, Q2TAB6

    10. XM_054340274.1 → XP_054196249.1  rab-like protein 2A isoform X5

      UniProtKB/TrEMBL
      Q6IC14

    11. XM_054340277.1 → XP_054196252.1  rab-like protein 2A isoform X6

      UniProtKB/Swiss-Prot
      B7ZBD6, Q9NU37, Q9UBK7

    12. XM_054340282.1 → XP_054196257.1  rab-like protein 2A isoform X8

      UniProtKB/TrEMBL
      A8MXF6, B7ZBD5, Q2TAB6

    13. XM_054340269.1 → XP_054196244.1  rab-like protein 2A isoform X3

    14. XM_054340284.1 → XP_054196259.1  rab-like protein 2A isoform X8

      UniProtKB/TrEMBL
      A8MXF6, B7ZBD5, Q2TAB6

    15. XM_054340262.1 → XP_054196237.1  rab-like protein 2A isoform X1

    16. XM_054340273.1 → XP_054196248.1  rab-like protein 2A isoform X5

      UniProtKB/TrEMBL
      Q6IC14

    17. XM_054340268.1 → XP_054196243.1  rab-like protein 2A isoform X3

    18. XM_054340275.1 → XP_054196250.1  rab-like protein 2A isoform X5

      UniProtKB/TrEMBL
      Q6IC14

    19. XM_054340270.1 → XP_054196245.1  rab-like protein 2A isoform X4

    20. XM_054340279.1 → XP_054196254.1  rab-like protein 2A isoform X6

      UniProtKB/Swiss-Prot
      B7ZBD6, Q9NU37, Q9UBK7

    21. XM_054340285.1 → XP_054196260.1  rab-like protein 2A isoform X9

      UniProtKB/TrEMBL
      A8MXF6, Q2TAB6

    22. XM_054340267.1 → XP_054196242.1  rab-like protein 2A isoform X3

    23. XM_054340266.1 → XP_054196241.1  rab-like protein 2A isoform X2

    24. XM_054340280.1 → XP_054196255.1  rab-like protein 2A isoform X7

      UniProtKB/TrEMBL
      A8MXF6, Q2TAB6

    25. XM_054340290.1 → XP_054196265.1  rab-like protein 2A isoform X13

    26. XM_054340289.1 → XP_054196264.1  rab-like protein 2A isoform X13

    27. XM_054340292.1 → XP_054196267.1  rab-like protein 2A isoform X14

    28. XM_054340291.1 → XP_054196266.1  rab-like protein 2A isoform X14

    29. XM_054340261.1 → XP_054196236.1  rab-like protein 2A isoform X1

    30. XM_054340264.1 → XP_054196239.1  rab-like protein 2A isoform X1

    31. XM_054340286.1 → XP_054196261.1  rab-like protein 2A isoform X11

    32. XM_054340288.1 → XP_054196263.1  rab-like protein 2A isoform X12

    33. XM_054340287.1 → XP_054196262.1  rab-like protein 2A isoform X11

    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9UBK7.1 GenPept UniProtKB/Swiss-Prot:Q9UBK7

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