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    Zfp952 zinc finger protein 952 [ Mus musculus (house mouse) ]

    Gene ID: 240067, updated on 8-Feb-2024

    Summary

    Official Symbol
    Zfp952provided by MGI
    Official Full Name
    zinc finger protein 952provided by MGI
    Primary source
    MGI:MGI:2441928
    See related
    Ensembl:ENSMUSG00000053390 AllianceGenome:MGI:2441928
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    C920016K16Rik
    Summary
    Predicted to enable DNA-binding transcription repressor activity, RNA polymerase II-specific and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Predicted to be involved in negative regulation of transcription by RNA polymerase II. [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Ubiquitous expression in CNS E18 (RPKM 3.4), CNS E14 (RPKM 3.0) and 25 other tissues See more
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    Genomic context

    See Zfp952 in Genome Data Viewer
    Location:
    17 B1; 17 17.98 cM
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 17 NC_000083.7 (33212083..33224431)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 17 NC_000083.6 (32993108..33005457)

    Chromosome 17 - NC_000083.7Genomic Context describing neighboring genes Neighboring gene cytochrome P450, family 4, subfamily f, polypeptide 41 pseudogene Neighboring gene STARR-positive B cell enhancer ABC_E7516 Neighboring gene zinc finger protein 472 Neighboring gene zinc finger protein 763 Neighboring gene CapStarr-seq enhancer MGSCv37_chr17:33170086-33170195 Neighboring gene CapStarr-seq enhancer MGSCv37_chr17:33170311-33170494 Neighboring gene PHD finger protein 8 like

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 

    General gene information

    Markers

    Clone Names

    • MGC67168

    Gene Ontology Provided by MGI

    Process Evidence Code Pubs
    involved_in regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    General protein information

    Preferred Names
    uncharacterized protein LOC240067

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001045559.1NP_001039024.1  uncharacterized protein LOC240067

      Status: VALIDATED

      Source sequence(s)
      BC051011, CA320661, CT033772
      Consensus CDS
      CCDS37559.1
      UniProtKB/TrEMBL
      B0V2W4, D3Z6L1
      Related
      ENSMUSP00000084949.5, ENSMUST00000087666.11
      Conserved Domains (5) summary
      smart00349
      Location:1050
      KRAB; krueppel associated box
      COG5048
      Location:234494
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:337357
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam01352
      Location:1049
      KRAB; KRAB box
      pfam13465
      Location:349374
      zf-H2C2_2; Zinc-finger double domain

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000083.7 Reference GRCm39 C57BL/6J

      Range
      33212083..33224431
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_030249795.2XP_030105655.1  uncharacterized protein LOC240067 isoform X2

      Conserved Domains (2) summary
      COG5048
      Location:197457
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:300320
      ZF_C2H2; C2H2 Zn finger [structural motif]
    2. XM_030249793.2XP_030105653.1  uncharacterized protein LOC240067 isoform X1

      Conserved Domains (3) summary
      COG5048
      Location:239499
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:342362
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam01352
      Location:1455
      KRAB; KRAB box
    3. XM_030249794.2XP_030105654.1  uncharacterized protein LOC240067 isoform X1

      Conserved Domains (3) summary
      COG5048
      Location:239499
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:342362
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam01352
      Location:1455
      KRAB; KRAB box
    4. XM_017317471.1XP_017172960.1  uncharacterized protein LOC240067 isoform X2

      Conserved Domains (2) summary
      COG5048
      Location:197457
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:300320
      ZF_C2H2; C2H2 Zn finger [structural motif]

    Suppressed Reference Sequence(s)

    The following Reference Sequences have been suppressed. Explain

    1. NM_199020.1: Suppressed sequence

      Description
      NM_199020.1: This RefSeq was permanently suppressed because it contains the wrong CDS.