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    Ccdc171 coiled-coil domain containing 171 [ Mus musculus (house mouse) ]

    Gene ID: 320226, updated on 28-Oct-2024

    Summary

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    Official Symbol
    Ccdc171provided by MGI
    Official Full Name
    coiled-coil domain containing 171provided by MGI
    Primary source
    MGI:MGI:1922152
    See related
    Ensembl:ENSMUSG00000052407 AllianceGenome:MGI:1922152
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    4930418J05Rik; 4930473A06Rik; A330015D16Rik
    Summary
    Is expressed in olfactory epithelium and trigeminal ganglion. Orthologous to human CCDC171 (coiled-coil domain containing 171). [provided by Alliance of Genome Resources, Oct 2024]
    Expression
    Broad expression in testis adult (RPKM 4.5), CNS E14 (RPKM 1.2) and 16 other tissues See more
    Orthologs
    human all
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    Genomic context

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    See Ccdc171 in Genome Data Viewer
    Location:
    4 C3; 4 39.46 cM
    Exon count:
    29
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 4 NC_000070.7 (83443649..83784380)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 4 NC_000070.6 (83525409..83866143)

    Chromosome 4 - NC_000070.7Genomic Context describing neighboring genes Neighboring gene STARR-positive B cell enhancer ABC_E10238 Neighboring gene ribosomal protein L34 pseudogene Neighboring gene predicted gene, 42308 Neighboring gene predicted gene, 25899 Neighboring gene CapStarr-seq enhancer MGSCv37_chr4:83213711-83213898 Neighboring gene DDB1 and CUL4 associated factor 12 pseudogene Neighboring gene chromobox 3, pseudogene 3 Neighboring gene predicted gene, 42309 Neighboring gene predicted gene 11415 Neighboring gene STARR-seq mESC enhancer starr_10651 Neighboring gene RIKEN cDNA 6030471H07 gene

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method. Piao Y, et al. Genome Res, 2001 Sep. PMID 11544199, Free PMC Article
    2. BioID screening of biotinylation sites using the avidin-like protein Tamavidin 2-REV identifies global interactors of stimulator of interferon genes (STING). Motani K, et al. J Biol Chem, 2020 Aug 7. PMID 32554809, Free PMC Article
    3. BayGenomics: a resource of insertional mutations in mouse embryonic stem cells. Stryke D, et al. Nucleic Acids Res, 2003 Jan 1. PMID 12520002, Free PMC Article
    4. Large-scale gene trapping in C57BL/6N mouse embryonic stem cells. Hansen GM, et al. Genome Res, 2008 Oct. PMID 18799693, Free PMC Article
    5. Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. Zambrowicz BP, et al. Proc Natl Acad Sci U S A, 2003 Nov 25. PMID 14610273, Free PMC Article

    See all (14) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Chemically induced (ENU) (1) 

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  

    General protein information

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    Preferred Names
    coiled-coil domain-containing protein 171

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001355378.1 → NP_001342307.1  coiled-coil domain-containing protein 171 isoform 1

      Status: VALIDATED

      Source sequence(s)
      AL928772, BB617255, BX682545, BX936355, BY715112, CD552966, CF915271, CJ055245
      Consensus CDS
      CCDS89772.1
      UniProtKB/Swiss-Prot
      E9Q1U1, Q8BLX2
      Related
      ENSMUSP00000155912.2, ENSMUST00000231339.2
      Conserved Domains (2) summary
      COG1196
      Location:464 → 1198
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      TIGR02168
      Location:58 → 818
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type

    2. NM_001355549.1 → NP_001342478.1  coiled-coil domain-containing protein 171 isoform 2

      Status: VALIDATED

      Source sequence(s)
      AK015563, AL928772, BB617255, BX682545, BX936355, CD552966, CF915271, CJ055245
      Conserved Domains (1) summary
      cl25732
      Location:8 → 648
      SMC_N; RecF/RecN/SMC N terminal domain

    3. NM_001369172.1 → NP_001356101.1  coiled-coil domain-containing protein 171 isoform 3

      Status: VALIDATED

      Source sequence(s)
      BX682545
      Conserved Domains (1) summary
      TIGR01843
      Location:33 → 149
      type_I_hlyD; type I secretion membrane fusion protein, HlyD family

    4. NM_001369173.1 → NP_001356102.1  coiled-coil domain-containing protein 171 isoform 4

      Status: VALIDATED

      Source sequence(s)
      BX682545
      Consensus CDS
      CCDS89771.1
      UniProtKB/TrEMBL
      S4R1F3
      Related
      ENSMUSP00000138195.2, ENSMUST00000126429.8
      Conserved Domains (1) summary
      PRK09039
      Location:50 → 117
      PRK09039; hypothetical protein; Validated

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000070.7 Reference GRCm39 C57BL/6J

      Range
      83443649..83784380
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006537992.4 → XP_006538055.1  coiled-coil domain-containing protein 171 isoform X4

      UniProtKB/Swiss-Prot
      E9Q1U1, Q8BLX2
      Conserved Domains (2) summary
      COG1196
      Location:464 → 1198
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      TIGR02168
      Location:58 → 731
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type

    2. XM_006537991.4 → XP_006538054.1  coiled-coil domain-containing protein 171 isoform X3

      UniProtKB/Swiss-Prot
      E9Q1U1, Q8BLX2
      Conserved Domains (2) summary
      COG1196
      Location:485 → 1204
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      TIGR02168
      Location:58 → 818
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type

    3. XM_006537990.5 → XP_006538053.1  coiled-coil domain-containing protein 171 isoform X2

      UniProtKB/Swiss-Prot
      E9Q1U1, Q8BLX2
      Conserved Domains (2) summary
      COG1196
      Location:420 → 1154
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      TIGR02168
      Location:58 → 774
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type

    4. XM_006537993.5 → XP_006538056.1  coiled-coil domain-containing protein 171 isoform X5

      Conserved Domains (2) summary
      COG1196
      Location:152 → 1032
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      TIGR02169
      Location:64 → 213
      SMC_prok_A; chromosome segregation protein SMC, primarily archaeal type

    5. XM_006537989.5 → XP_006538052.1  coiled-coil domain-containing protein 171 isoform X1

      See identical proteins and their annotated locations for XP_006538052.1

      UniProtKB/Swiss-Prot
      E9Q1U1, Q8BLX2
      Related
      ENSMUSP00000056520.7, ENSMUST00000053414.13
      Conserved Domains (2) summary
      COG1196
      Location:464 → 1198
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      TIGR02168
      Location:58 → 818
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type

    Suppressed Reference Sequence(s)

    The following Reference Sequences have been suppressed. Explain

    1. NM_001081012.1: Suppressed sequence

      Description
      NM_001081012.1: This RefSeq was removed because currently there is insufficient support for the transcript and the protein.

    2. NM_029117.1: Suppressed sequence

      Description
      NM_029117.1: This RefSeq was permanently suppressed because it is a nonsense-mediated mRNA decay (NMD) candidate.

    3. NM_177108.2: Suppressed sequence

      Description
      NM_177108.2: This RefSeq was permanently suppressed because it is a nonsense-mediated mRNA decay (NMD) candidate.
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    E9Q1U1.1 GenPept UniProtKB/Swiss-Prot:E9Q1U1

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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