ADARB1 adenosine deaminase RNA specific B1 [Homo sapiens (human)] - Gene

Summary

Official Symbol: ADARB1provided by HGNC
Official Full Name: adenosine deaminase RNA specific B1provided by HGNC
Primary source: HGNC:HGNC:226
See related: Ensembl:ENSG00000197381 MIM:601218; AllianceGenome:HGNC:226
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Homo sapiens
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as: RED1; ADAR2; DRABA2; DRADA2; NEDHYMS
Summary: This gene encodes the enzyme responsible for pre-mRNA editing of the glutamate receptor subunit B by site-specific deamination of adenosines. Studies in rat found that this enzyme acted on its own pre-mRNA molecules to convert an AA dinucleotide to an AI dinucleotide which resulted in a new splice site. Alternative splicing of this gene results in several transcript variants, some of which have been characterized by the presence or absence of an ALU cassette insert and a short or long C-terminal region. [provided by RefSeq, Jul 2008]
Expression: Ubiquitous expression in lung (RPKM 5.2), urinary bladder (RPKM 3.4) and 24 other tissues See more
Orthologs: mouse all
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Genomic context

Location:: 21q22.3

Exon count:: 21

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCh38.p14 (GCF_000001405.40)	21	NC_000021.9 (45074578..45226563)
RS_2024_08	current	T2T-CHM13v2.0 (GCF_009914755.1)	21	NC_060945.1 (43436861..43590594)
RS_2024_09	previous assembly	GRCh37.p13 (GCF_000001405.25)	21	NC_000021.8 (46494493..46646478)

Chromosome 21 - NC_000021.9 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: HPA RNA-seq normal tissues HPA RNA-seq normal tissues
Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
BioProject: PRJEB4337
Publication: PMID 24309898
Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Orchestration of a blood-derived and ADARB1-centred network in Alzheimer's and Parkinson's disease.
Title: Orchestration of a blood-derived and ADARB1-centred network in Alzheimer's and Parkinson's disease.
Core-binding factor fusion downregulation of ADAR2 RNA editing contributes to AML leukemogenesis.
Title: Core-binding factor fusion downregulation of ADAR2 RNA editing contributes to AML leukemogenesis.
Targeting the androgen receptor to enhance NK cell killing efficacy in bladder cancer by modulating ADAR2/circ_0001005/PD-L1 signaling.
Title: Targeting the androgen receptor to enhance NK cell killing efficacy in bladder cancer by modulating ADAR2/circ_0001005/PD-L1 signaling.
ADAR2 enzymes: efficient site-specific RNA editors with gene therapy aspirations.
Title: ADAR2 enzymes: efficient site-specific RNA editors with gene therapy aspirations.
Comprehensive interrogation of the ADAR2 deaminase domain for engineering enhanced RNA editing activity and specificity.
Title: Comprehensive interrogation of the ADAR2 deaminase domain for engineering enhanced RNA editing activity and specificity.
Developing PspCas13b-based enhanced RESCUE system, eRESCUE, with efficient RNA base editing.
Title: Developing PspCas13b-based enhanced RESCUE system, eRESCUE, with efficient RNA base editing.
Biallelic variants in ADARB1, encoding a dsRNA-specific adenosine deaminase, cause a severe developmental and epileptic encephalopathy.
Title: Biallelic variants in ADARB1, encoding a dsRNA-specific adenosine deaminase, cause a severe developmental and epileptic encephalopathy.
Short-Chain Guide RNA for Site-Directed A-to-I RNA Editing.
Title: Short-Chain Guide RNA for Site-Directed A-to-I RNA Editing.
ADAR-mediated RNA editing of DNA:RNA hybrids is required for DNA double strand break repair.
Title: ADAR-mediated RNA editing of DNA:RNA hybrids is required for DNA double strand break repair.
What do editors do? Understanding the physiological functions of A-to-I RNA editing by adenosine deaminase acting on RNAs.
Title: What do editors do? Understanding the physiological functions of A-to-I RNA editing by adenosine deaminase acting on RNAs.

Submit: New GeneRIF Correction See all GeneRIFs (72)

Phenotypes

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Find tests for this gene in the NIH Genetic Testing Registry (GTR)

Review eQTL and phenotype association data in this region using PheGenI

Associated conditions

Description	Tests
Neurodevelopmental disorder with hypotonia, microcephaly, and seizures MedGen: C5394312 OMIM: 618862 GeneReviews: Not available	not available

EBI GWAS Catalog

Description
Framingham Heart Study genome-wide association: results for pulmonary function measures. EBI GWAS Catalog EBI GWAS CatalogPubMed

Variation

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See variants in ClinVar

See studies and variants in dbVar

See Variation Viewer (GRCh37.p13)

See Variation Viewer (GRCh38)

HIV-1 interactions

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Protein interactions

Protein	Gene	Interaction	Pubs
Envelope surface glycoprotein gp120	env	HIV-1 gp120 inhibits adenosine deaminase (ADA) binding to CD26 (dipeptidyl-peptidase 4) in both CD4+ and CD4- cells; this effect requires the interaction of gp120 with CD4 or CXCR4	PubMed

Go to the HIV-1, Human Interaction Database

Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Markers

Cda0pa11 (e-PCR)
- UniSTS:74782

SHGC-87694 (e-PCR)
- UniSTS:13608

G23228 (e-PCR)
- UniSTS:83279

Adarb1 (e-PCR), detects polymorphism
- UniSTS:479065

RH80251 (e-PCR)
- UniSTS:88414

RH122581 (e-PCR)
- UniSTS:138644

UniSTS:259034 (e-PCR)
- UniSTS:259034

Adarb1 (e-PCR), detects polymorphism
- UniSTS:259034

ADARB1_1459 (e-PCR)
- UniSTS:276972

D21S1720E (e-PCR)
- UniSTS:150776

Gene Ontology Provided by GOA

Function	Evidence Code	Pubs
enables RNA binding	EXP Inferred from Experiment more info	PubMed
enables RNA binding	HDA more info	PubMed
enables RNA binding	IDA Inferred from Direct Assay more info	PubMed
enables adenosine deaminase activity	IEA Inferred from Electronic Annotation more info
enables double-stranded RNA adenosine deaminase activity	IBA Inferred from Biological aspect of Ancestor more info
enables double-stranded RNA adenosine deaminase activity	IDA Inferred from Direct Assay more info	PubMed
enables double-stranded RNA binding	IBA Inferred from Biological aspect of Ancestor more info
enables double-stranded RNA binding	IDA Inferred from Direct Assay more info	PubMed
enables identical protein binding	IPI Inferred from Physical Interaction more info	PubMed
enables mRNA binding	TAS Traceable Author Statement more info	PubMed
enables metal ion binding	IEA Inferred from Electronic Annotation more info
enables protein binding	IPI Inferred from Physical Interaction more info	PubMed
enables tRNA-specific adenosine deaminase activity	IBA Inferred from Biological aspect of Ancestor more info

Process	Evidence Code	Pubs
involved_in RNA processing	IBA Inferred from Biological aspect of Ancestor more info
involved_in RNA processing	IDA Inferred from Direct Assay more info	PubMed
involved_in adenosine to inosine editing	IBA Inferred from Biological aspect of Ancestor more info
involved_in adenosine to inosine editing	IDA Inferred from Direct Assay more info	PubMed
involved_in base conversion or substitution editing	IC Inferred by Curator more info	PubMed
involved_in base conversion or substitution editing	IDA Inferred from Direct Assay more info	PubMed
involved_in defense response to virus	IEA Inferred from Electronic Annotation more info
involved_in facial nerve morphogenesis	IEA Inferred from Electronic Annotation more info
involved_in hypoglossal nerve morphogenesis	IEA Inferred from Electronic Annotation more info
involved_in innate immune response	IEA Inferred from Electronic Annotation more info
involved_in innervation	IEA Inferred from Electronic Annotation more info
involved_in mRNA processing	IEA Inferred from Electronic Annotation more info
involved_in motor behavior	IEA Inferred from Electronic Annotation more info
involved_in motor neuron apoptotic process	IEA Inferred from Electronic Annotation more info
involved_in multicellular organism growth	IEA Inferred from Electronic Annotation more info
involved_in muscle tissue morphogenesis	IEA Inferred from Electronic Annotation more info
involved_in negative regulation of cell migration	IDA Inferred from Direct Assay more info	PubMed
involved_in negative regulation of cell population proliferation	IDA Inferred from Direct Assay more info	PubMed
involved_in negative regulation of protein kinase activity by regulation of protein phosphorylation	IDA Inferred from Direct Assay more info	PubMed
involved_in neuromuscular process controlling posture	IEA Inferred from Electronic Annotation more info
involved_in neuromuscular synaptic transmission	IEA Inferred from Electronic Annotation more info
involved_in positive regulation of viral genome replication	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in regulation of cell cycle	IDA Inferred from Direct Assay more info	PubMed
involved_in spinal cord ventral commissure morphogenesis	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
is_active_in cytoplasm	IBA Inferred from Biological aspect of Ancestor more info
located_in cytosol	IDA Inferred from Direct Assay more info
is_active_in nucleolus	IBA Inferred from Biological aspect of Ancestor more info
located_in nucleolus	IDA Inferred from Direct Assay more info	PubMed
located_in nucleoplasm	IDA Inferred from Direct Assay more info
located_in nucleoplasm	TAS Traceable Author Statement more info
located_in nucleus	IDA Inferred from Direct Assay more info	PubMed
located_in synapse	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: double-stranded RNA-specific editase 1

Names: RNA editing deaminase 1; RNA-editing enzyme 1; adenosine deaminase, RNA-specific, B1 (homolog of rat RED1); dsRNA adenosine deaminase DRADA2

NP_001103.1

EC 3.5.4.37

NP_001153702.1

EC 3.5.4.37

NP_001333616.1

EC 3.5.4.37

NP_001333617.1

EC 3.5.4.37

NP_001397651.1

EC 3.5.4.37

NP_056648.1

EC 3.5.4.37

NP_056649.1

EC 3.5.4.37

XP_016883733.1

EC 3.5.4.37

XP_016883740.1

EC 3.5.4.37

XP_016883742.1

EC 3.5.4.37

XP_047296616.1

EC 3.5.4.37

XP_047296617.1

EC 3.5.4.37

XP_047296618.1

EC 3.5.4.37

XP_047296619.1

EC 3.5.4.37

XP_047296620.1

EC 3.5.4.37

XP_047296621.1

EC 3.5.4.37

XP_047296622.1

EC 3.5.4.37

XP_047296623.1

EC 3.5.4.37

XP_054180277.1

EC 3.5.4.37

XP_054180278.1

EC 3.5.4.37

XP_054180279.1

EC 3.5.4.37

XP_054180280.1

EC 3.5.4.37

XP_054180281.1

EC 3.5.4.37

XP_054180282.1

EC 3.5.4.37

XP_054180283.1

EC 3.5.4.37

XP_054180284.1

EC 3.5.4.37

XP_054180285.1

EC 3.5.4.37

XP_054180286.1

EC 3.5.4.37

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

NG_052015.1 RefSeqGene

Range

5003..156983

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_001112.4 → NP_001103.1 double-stranded RNA-specific editase 1 isoform 1

See identical proteins and their annotated locations for NP_001103.1

Status: REVIEWED

Description

Transcript Variant: This variant (1), also known as ADAR2a-L1 or DRADA2a, lacks the ALU cassette insert and contains the long C-terminal region, as compared to variant 2. The resulting isoform (1), also known as hRED1-Short, lacks an internal segment, compared to isoform 2.

Source sequence(s)

AB194370, BC030663, BU726292

Consensus CDS

CCDS33590.1

UniProtKB/TrEMBL

Q86XN4

Related

ENSP00000015877.6, ENST00000348831.9

Conserved Domains (2) summary

smart00552
Location:322 → 698

ADEAMc; tRNA-specific and double-stranded RNA adenosine deaminase (RNA-specific editase)

cd00048
Location:79 → 142

DSRM; Double-stranded RNA binding motif. Binding is not sequence specific but is highly specific for double stranded RNA. Found in a variety of proteins including dsRNA dependent protein kinase PKR, RNA helicases, Drosophila staufen protein, E. coli RNase III, ...
NM_001160230.2 → NP_001153702.1 double-stranded RNA-specific editase 1 isoform 7

See identical proteins and their annotated locations for NP_001153702.1

Status: REVIEWED

Description

Transcript Variant: This variant (7), also known as ADAR2d, lacks the ALU cassette insert and an alternate segment in the 3' coding region, compared to variant 2. The resulting isoform (7) lacks an internal segment and has a shorter and distinct C-terminus, compared to isoform 2, and contains the short C-terminal region. Variants 7 and 10 encode the same isoform.

Source sequence(s)

AB194373, BC030663, BU726292

UniProtKB/TrEMBL

Q86XN4

Conserved Domains (2) summary

smart00552
Location:322 → 672

ADEAMc; tRNA-specific and double-stranded RNA adenosine deaminase (RNA-specific editase)

cd00048
Location:79 → 142

DSRM; Double-stranded RNA binding motif. Binding is not sequence specific but is highly specific for double stranded RNA. Found in a variety of proteins including dsRNA dependent protein kinase PKR, RNA helicases, Drosophila staufen protein, E. coli RNase III, ...
NM_001346687.2 → NP_001333616.1 double-stranded RNA-specific editase 1 isoform 8

Status: REVIEWED

Source sequence(s)

AL133499, BU726292, BX322560, FJ169506

Consensus CDS

CCDS93105.1

UniProtKB/TrEMBL

A0A994J4V7, O43263

Related

ENSP00000516123.1, ENST00000705393.1
NM_001346688.2 → NP_001333617.1 double-stranded RNA-specific editase 1 isoform 7

Status: REVIEWED

Description

Transcript Variant: Variants 7 and 10 encode the same isoform (7).

Source sequence(s)

AL133499, AP001579, BU726292, BX322560

UniProtKB/TrEMBL

Q86XN4
NM_001410722.1 → NP_001397651.1 double-stranded RNA-specific editase 1 isoform 9

Status: REVIEWED

Source sequence(s)

AL133499, BX322560

Consensus CDS

CCDS93106.1

UniProtKB/TrEMBL

A0A994J7T5

Related

ENSP00000516122.1, ENST00000705392.1
NM_015833.4 → NP_056648.1 double-stranded RNA-specific editase 1 isoform 2

See identical proteins and their annotated locations for NP_056648.1

Status: REVIEWED

Description

Transcript Variant: This variant (2), also known as DRADA2b, represents the longest transcript, which includes the ALU cassette insert and the long C-terminal region. It encodes the longest isoform (2), also known as hRED1-Long.

Source sequence(s)

AB194370, BC030663, BU726292, U76421

Consensus CDS

CCDS33589.1

UniProtKB/Swiss-Prot

A6NFK8, A6NJ84, C3TTQ1, C3TTQ2, C9JUP4, G5E9B4, O00395, O00465, O00691, O00692, P78555, P78563, Q4AE77, Q4AE79, Q6P0M9, Q8NFA1, Q8NFD1

UniProtKB/TrEMBL

O43263

Related

ENSP00000353920.3, ENST00000360697.4

Conserved Domains (3) summary

smart00552
Location:322 → 738

ADEAMc; tRNA-specific and double-stranded RNA adenosine deaminase (RNA-specific editase)

cd19895
Location:75 → 146

DSRM_RED1_rpt1; first double-stranded RNA binding motif of RNA-editing deaminase 1 (RED1) and similar proteins

cd19898
Location:232 → 301

DSRM_RED1_rpt2; second double-stranded RNA binding motif of RNA-editing deaminase 1 (RED1) and similar proteins
NM_015834.4 → NP_056649.1 double-stranded RNA-specific editase 1 isoform 3

See identical proteins and their annotated locations for NP_056649.1

Status: REVIEWED

Description

Transcript Variant: This variant (3), also known as DRADA2c, lacks an alternate segment in the 3' coding region, compared to variant 2. The resulting isoform (3) has a shorter and distinct C-terminus, compared to isoform 2, and contains the ALU cassette insert and the short C-terminal region.

Source sequence(s)

BC030663, BU726292, U76422

Consensus CDS

CCDS42970.1

UniProtKB/TrEMBL

O43263

Related

ENSP00000374513.4, ENST00000389863.8

Conserved Domains (3) summary

smart00552
Location:322 → 712

ADEAMc; tRNA-specific and double-stranded RNA adenosine deaminase (RNA-specific editase)

cd00048
Location:79 → 142

DSRM; Double-stranded RNA binding motif. Binding is not sequence specific but is highly specific for double stranded RNA. Found in a variety of proteins including dsRNA dependent protein kinase PKR, RNA helicases, Drosophila staufen protein, E. coli RNase III, ...

pfam13900
Location:471 → 496

GVQW; Putative domain of unknown function

RNA

NR_027672.2 RNA Sequence

Status: REVIEWED

Description

Transcript Variant: This variant (5), also known as ADAR2g, lacks the second coding exon, the ALU cassette insert, and a segment of the 3' UTR, compared to transcript variant 2. This variant is represented as non-coding because the use of the 5'-most supported translational start codon, as used in variant 2, renders the transcript a candidate for nonsense-mediated mRNA decay (NMD), and no protein is expressed by in vitro translation according to Kawahara et al. (PMID: 16297572).

Source sequence(s)

AB194369, BC030663, BU726292
NR_027673.1 RNA Sequence

Status: REVIEWED

Description

Transcript Variant: This variant (4) contains an additional 5' exon, lacks the ALU cassette, and lacks a segment of the 3' UTR, compared to variant 2. This variant is represented as non-coding because it contains an uORF that is predicted to inhibit translation of the primary ORF. The transcript is also a candidate for nonsense-mediated mRNA decay (NMD).

Source sequence(s)

AB194370, AY135659, BC030663, BU726292
NR_027674.2 RNA Sequence

Status: REVIEWED

Description

Transcript Variant: This variant (6), also known as ADAR2a-L2, lacks the ALU cassette insert and a segment of the 3' UTR, compared to variant 2. This variant is represented as non-coding because the additional splicing in the 3' UTR renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).

Source sequence(s)

AB194371, BC030663, BU726292
NR_073200.2 RNA Sequence

Status: REVIEWED

Description

Transcript Variant: This variant (8) lacks an internal portion of the last exon compared to variant 2. This variant is represented as non-coding because the additional splicing in the 3' UTR renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).

Source sequence(s)

BC030663, BU726292, U76421
NR_144483.2 RNA Sequence

Status: REVIEWED

Source sequence(s)

AB194372, BC030663, BU726292

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

NC_000021.9 Reference GRCh38.p14 Primary Assembly

Range

45074578..45226563

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_017028251.2 → XP_016883740.1 double-stranded RNA-specific editase 1 isoform X5

UniProtKB/Swiss-Prot

A6NFK8, A6NJ84, C3TTQ1, C3TTQ2, C9JUP4, G5E9B4, O00395, O00465, O00691, O00692, P78555, P78563, Q4AE77, Q4AE79, Q6P0M9, Q8NFA1, Q8NFD1

UniProtKB/TrEMBL

O43263

Related

ENSP00000387480.2, ENST00000449478.2

Conserved Domains (3) summary

smart00552
Location:322 → 738

ADEAMc; tRNA-specific and double-stranded RNA adenosine deaminase (RNA-specific editase)

cd19895
Location:75 → 146

DSRM_RED1_rpt1; first double-stranded RNA binding motif of RNA-editing deaminase 1 (RED1) and similar proteins

cd19898
Location:232 → 301

DSRM_RED1_rpt2; second double-stranded RNA binding motif of RNA-editing deaminase 1 (RED1) and similar proteins
XM_047440660.1 → XP_047296616.1 double-stranded RNA-specific editase 1 isoform X1
XM_047440661.1 → XP_047296617.1 double-stranded RNA-specific editase 1 isoform X1
XM_047440665.1 → XP_047296621.1 double-stranded RNA-specific editase 1 isoform X5

UniProtKB/Swiss-Prot

A6NFK8, A6NJ84, C3TTQ1, C3TTQ2, C9JUP4, G5E9B4, O00395, O00465, O00691, O00692, P78555, P78563, Q4AE77, Q4AE79, Q6P0M9, Q8NFA1, Q8NFD1
XM_047440667.1 → XP_047296623.1 double-stranded RNA-specific editase 1 isoform X8
XM_047440662.1 → XP_047296618.1 double-stranded RNA-specific editase 1 isoform X2
XM_047440663.1 → XP_047296619.1 double-stranded RNA-specific editase 1 isoform X4
XM_047440666.1 → XP_047296622.1 double-stranded RNA-specific editase 1 isoform X7
XM_047440664.1 → XP_047296620.1 double-stranded RNA-specific editase 1 isoform X5

UniProtKB/Swiss-Prot

A6NFK8, A6NJ84, C3TTQ1, C3TTQ2, C9JUP4, G5E9B4, O00395, O00465, O00691, O00692, P78555, P78563, Q4AE77, Q4AE79, Q6P0M9, Q8NFA1, Q8NFD1
XM_017028244.3 → XP_016883733.1 double-stranded RNA-specific editase 1 isoform X3

UniProtKB/TrEMBL

O43263
XM_017028253.3 → XP_016883742.1 double-stranded RNA-specific editase 1 isoform X6

UniProtKB/TrEMBL

Q86XN4

RNA

XR_001754787.3 RNA Sequence
XR_007067777.1 RNA Sequence
XR_007067778.1 RNA Sequence
XR_001754792.3 RNA Sequence
XR_001754791.3 RNA Sequence

Alternate T2T-CHM13v2.0

Genomic

NC_060945.1 Alternate T2T-CHM13v2.0

Range

43436861..43590594

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_054324308.1 → XP_054180283.1 double-stranded RNA-specific editase 1 isoform X5

UniProtKB/Swiss-Prot

A6NFK8, A6NJ84, C3TTQ1, C3TTQ2, C9JUP4, G5E9B4, O00395, O00465, O00691, O00692, P78555, P78563, Q4AE77, Q4AE79, Q6P0M9, Q8NFA1, Q8NFD1
XM_054324302.1 → XP_054180277.1 double-stranded RNA-specific editase 1 isoform X1
XM_054324307.1 → XP_054180282.1 double-stranded RNA-specific editase 1 isoform X5

UniProtKB/Swiss-Prot

A6NFK8, A6NJ84, C3TTQ1, C3TTQ2, C9JUP4, G5E9B4, O00395, O00465, O00691, O00692, P78555, P78563, Q4AE77, Q4AE79, Q6P0M9, Q8NFA1, Q8NFD1
XM_054324311.1 → XP_054180286.1 double-stranded RNA-specific editase 1 isoform X8
XM_054324303.1 → XP_054180278.1 double-stranded RNA-specific editase 1 isoform X2
XM_054324305.1 → XP_054180280.1 double-stranded RNA-specific editase 1 isoform X4
XM_054324310.1 → XP_054180285.1 double-stranded RNA-specific editase 1 isoform X7
XM_054324306.1 → XP_054180281.1 double-stranded RNA-specific editase 1 isoform X5

UniProtKB/Swiss-Prot

A6NFK8, A6NJ84, C3TTQ1, C3TTQ2, C9JUP4, G5E9B4, O00395, O00465, O00691, O00692, P78555, P78563, Q4AE77, Q4AE79, Q6P0M9, Q8NFA1, Q8NFD1
XM_054324304.1 → XP_054180279.1 double-stranded RNA-specific editase 1 isoform X3
XM_054324309.1 → XP_054180284.1 double-stranded RNA-specific editase 1 isoform X6

RNA

XR_008485323.1 RNA Sequence
XR_008485324.1 RNA Sequence
XR_008485325.1 RNA Sequence
XR_008485326.1 RNA Sequence
XR_008485327.1 RNA Sequence

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

NM_001033049.1: Suppressed sequence

Description

NM_001033049.1: This RefSeq was permanently suppressed because it is a nonsense-mediated mRNA decay (NMD) candidate, and the annotated CDS is unlikely to be translated because of an upstream ORF.