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These reference sequences exist independently of genome builds. Explain
These reference sequences are curated independently of the genome
annotation cycle, so their versions may not match the RefSeq versions in the current
genome build. Identify version mismatches by comparing the version of the RefSeq in
this section to the one reported in Genomic regions,
transcripts, and products above.
mRNA and Protein(s)
-
NM_001164883.2 → NP_001158355.1 catenin alpha-2 isoform 2
Status: VALIDATED
- Description
- Transcript Variant: This variant (2) lacks two consecutive exons in the 3' coding region but maintains the reading frame compared to variant 1. The resulting isoform (2) lacks an internal segment near the C-terminus compared to isoform 3.
- Source sequence(s)
-
AK295181, BC052996, DA313393
- Consensus CDS
-
CCDS54371.1
- UniProtKB/Swiss-Prot
-
P26232
- Related
- ENSP00000486160.1, ENST00000629316.2
- Conserved Domains (1) summary
-
- pfam01044
Location:81 → 821
- Vinculin; Vinculin family
-
NM_001282597.3 → NP_001269526.1 catenin alpha-2 isoform 3
Status: VALIDATED
- Description
- Transcript Variant: This variant (3) encodes the longest isoform (3).
- Source sequence(s)
-
AC008067, AC010975, AC011741, AC011746, AC096573, AC096753, AC104780, FJ695201
- Consensus CDS
-
CCDS62944.1
- UniProtKB/Swiss-Prot
- B3KXE5, B7Z2W7, B7Z352, B7Z898, P26232, Q4ZFW1, Q53R26, Q53R33, Q53T67, Q53T71, Q53TM8, Q7Z3L1, Q7Z3Y0
- Related
- ENSP00000384638.4, ENST00000402739.9
- Conserved Domains (1) summary
-
- pfam01044
Location:81 → 914
- Vinculin; Vinculin family
-
NM_001282598.2 → NP_001269527.1 catenin alpha-2 isoform 4
Status: VALIDATED
- Description
- Transcript Variant: This variant (4) has an alternate 5' terminal exon that includes an upstream in-frame AUG start codon, and lacks an in-frame exon in the 3' coding region, compared to variant 3. The resulting isoform (4) is longer at the N-terminus but lacks an internal segment near the C-terminus compared to isoform 3.
- Source sequence(s)
-
AC010975, AK303035, BC052996
- UniProtKB/Swiss-Prot
-
P26232
- Conserved Domains (1) summary
-
- pfam01044
Location:115 → 900
- Vinculin; Vinculin family
-
NM_001282599.2 → NP_001269528.1 catenin alpha-2 isoform 5
Status: VALIDATED
- Description
- Transcript Variant: This variant (5) differs in the 5' UTR and has multiple coding region differences compared to variant 3. These differences include translation initiation at an alternate AUG start codon. The resulting isoform (5) has a shorter and distinct N-terminus and lacks an internal segment near the C-terminus compared to isoform 3.
- Source sequence(s)
-
BC052996, BX537769
- Consensus CDS
-
CCDS62945.1
- UniProtKB/TrEMBL
-
A0A0A0MRI5
- Related
- ENSP00000341500.3, ENST00000343114.7
- Conserved Domains (1) summary
-
- pfam01044
Location:32 → 545
- Vinculin; Vinculin family
-
NM_001282600.2 → NP_001269529.1 catenin alpha-2 isoform 6
Status: VALIDATED
- Description
- Transcript Variant: This variant (6) has an alternate exon in the 5' UTR and has multiple coding region differences compared to variant 3. These differences include translation initiation at a downstream AUG start codon. The resulting isoform (6) is shorter at the N-terminus and lacks an internal segment near the C-terminus compared to isoform 3.
- Source sequence(s)
-
BC052996, BI599815, HQ589336
- Consensus CDS
-
CCDS74531.1
- UniProtKB/TrEMBL
- A0A0A0MRI5, F6KRI5
- Related
- ENSP00000444675.2, ENST00000541047.5
- Conserved Domains (1) summary
-
- pfam01044
Location:1 → 498
- Vinculin; Vinculin family
-
NM_001320810.2 → NP_001307739.1 catenin alpha-2 isoform 7
Status: VALIDATED
- Description
- Transcript Variant: This variant (7) differs in the 5' UTR and coding sequence compared to variant 3. This difference includes translation initiation at a downstream AUG start codon. The resulting isoform (7) is shorter at the N-terminus compared to isoform 3.
- Source sequence(s)
-
AC008067, BI599815, BX648368, M94151
- UniProtKB/TrEMBL
-
A0A0A0MRI5
- Related
- ENSP00000355398.5, ENST00000361291.8
- Conserved Domains (1) summary
-
- pfam01044
Location:1 → 546
- Vinculin; Vinculin family
-
NM_001399737.1 → NP_001386666.1 catenin alpha-2 isoform 1
Status: VALIDATED
- Description
- Transcript Variant: This variant (8) lacks an in-frame exon in the 3' coding region compared to variant 3 and differs in the 5' UTR. The resulting isoform (1) lacks an internal segment near the C-terminus compared to isoform 3. Variants 1 and 8 encode the same isoform (1).
- Source sequence(s)
-
AC008067, AC010975, AC011741, AC011746, AC011754, AC018733, AC096573, AC096753, AC104780, FJ695201
- Consensus CDS
-
CCDS42703.2
- Related
- ENSP00000418191.1, ENST00000466387.5
- Conserved Domains (1) summary
-
- pfam01044
Location:81 → 866
- Vinculin; Vinculin family
-
NM_004389.4 → NP_004380.2 catenin alpha-2 isoform 1
Status: VALIDATED
- Description
- Transcript Variant: This variant (1) lacks an in-frame exon in the 3' coding region compared to variant 3. The resulting isoform (1) lacks an internal segment near the C-terminus compared to isoform 3. Variants 1 and 8 encode the same isoform (1).
- Source sequence(s)
-
BC040458, BC052996, DA313393
- Consensus CDS
-
CCDS42703.2
- UniProtKB/Swiss-Prot
-
P26232
- UniProtKB/TrEMBL
-
Q49AD3
- Related
- ENSP00000419295.1, ENST00000496558.5
- Conserved Domains (1) summary
-
- pfam01044
Location:81 → 866
- Vinculin; Vinculin family
The following sections contain reference sequences that belong to a
specific genome build. Explain
This section includes genomic Reference
Sequences (RefSeqs) from all assemblies on which this gene is annotated, such as
RefSeqs for chromosomes and scaffolds (contigs) from both reference and alternate
assemblies. Model RNAs and proteins are also reported here.
Reference GRCh38.p14 Primary Assembly
Genomic
-
NC_000002.12 Reference GRCh38.p14 Primary Assembly
- Range
-
79185377..80648780
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
mRNA and Protein(s)
-
XM_024452714.2 → XP_024308482.1 catenin alpha-2 isoform X1
- UniProtKB/Swiss-Prot
- B3KXE5, B7Z2W7, B7Z352, B7Z898, P26232, Q4ZFW1, Q53R26, Q53R33, Q53T67, Q53T71, Q53TM8, Q7Z3L1, Q7Z3Y0
- Conserved Domains (1) summary
-
- pfam01044
Location:81 → 914
- Vinculin; Vinculin family
-
XM_011532556.3 → XP_011530858.1 catenin alpha-2 isoform X1
- UniProtKB/Swiss-Prot
- B3KXE5, B7Z2W7, B7Z352, B7Z898, P26232, Q4ZFW1, Q53R26, Q53R33, Q53T67, Q53T71, Q53TM8, Q7Z3L1, Q7Z3Y0
- Conserved Domains (1) summary
-
- pfam01044
Location:81 → 914
- Vinculin; Vinculin family
-
XM_017003403.3 → XP_016858892.1 catenin alpha-2 isoform X2
- UniProtKB/Swiss-Prot
-
P26232
- Conserved Domains (1) summary
-
- pfam01044
Location:81 → 866
- Vinculin; Vinculin family
-
XM_047443447.1 → XP_047299403.1 catenin alpha-2 isoform X3
-
XM_017003405.3 → XP_016858894.1 catenin alpha-2 isoform X4
-
XM_024452715.2 → XP_024308483.1 catenin alpha-2 isoform X1
- UniProtKB/Swiss-Prot
- B3KXE5, B7Z2W7, B7Z352, B7Z898, P26232, Q4ZFW1, Q53R26, Q53R33, Q53T67, Q53T71, Q53TM8, Q7Z3L1, Q7Z3Y0
- Conserved Domains (1) summary
-
- pfam01044
Location:81 → 914
- Vinculin; Vinculin family
-
XM_011532557.3 → XP_011530859.1 catenin alpha-2 isoform X5
- UniProtKB/TrEMBL
-
A0A0A0MRI5
- Conserved Domains (1) summary
-
- pfam01044
Location:1 → 465
- Vinculin; Vinculin family
Alternate T2T-CHM13v2.0
Genomic
-
NC_060926.1 Alternate T2T-CHM13v2.0
- Range
-
79185703..80649017
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
mRNA and Protein(s)
-
XM_054340643.1 → XP_054196618.1 catenin alpha-2 isoform X1
- UniProtKB/Swiss-Prot
- B3KXE5, B7Z2W7, B7Z352, B7Z898, P26232, Q4ZFW1, Q53R26, Q53R33, Q53T67, Q53T71, Q53TM8, Q7Z3L1, Q7Z3Y0
-
XM_054340642.1 → XP_054196617.1 catenin alpha-2 isoform X1
- UniProtKB/Swiss-Prot
- B3KXE5, B7Z2W7, B7Z352, B7Z898, P26232, Q4ZFW1, Q53R26, Q53R33, Q53T67, Q53T71, Q53TM8, Q7Z3L1, Q7Z3Y0
-
XM_054340644.1 → XP_054196619.1 catenin alpha-2 isoform X2
-
XM_054340645.1 → XP_054196620.1 catenin alpha-2 isoform X3
-
XM_054340646.1 → XP_054196621.1 catenin alpha-2 isoform X4
-
XM_054340641.1 → XP_054196616.1 catenin alpha-2 isoform X1
- UniProtKB/Swiss-Prot
- B3KXE5, B7Z2W7, B7Z352, B7Z898, P26232, Q4ZFW1, Q53R26, Q53R33, Q53T67, Q53T71, Q53TM8, Q7Z3L1, Q7Z3Y0
-
XM_054340647.1 → XP_054196622.1 catenin alpha-2 isoform X5
- UniProtKB/TrEMBL
-
A0A0A0MRI5