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    ZC3H11A zinc finger CCCH-type containing 11A [ Homo sapiens (human) ]

    Gene ID: 9877, updated on 2-Nov-2024

    Summary

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    Official Symbol
    ZC3H11Aprovided by HGNC
    Official Full Name
    zinc finger CCCH-type containing 11Aprovided by HGNC
    Primary source
    HGNC:HGNC:29093
    See related
    Ensembl:ENSG00000058673 MIM:613513; AllianceGenome:HGNC:29093
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    ZC3HDC11A
    Summary
    Enables RNA binding activity. Involved in poly(A)+ mRNA export from nucleus. Located in transcription export complex. [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Ubiquitous expression in skin (RPKM 33.1), lymph node (RPKM 28.6) and 25 other tissues See more
    Orthologs
    mouse all
    NEW
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    Genomic context

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    See ZC3H11A in Genome Data Viewer
    Location:
    1q32.1
    Exon count:
    20
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 1 NC_000001.11 (203795623..203854124)
    RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 1 NC_060925.1 (203058813..203118077)
    RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 1 NC_000001.10 (203764751..203823252)

    Chromosome 1 - NC_000001.11Genomic Context describing neighboring genes Neighboring gene ATPase plasma membrane Ca2+ transporting 4 Neighboring gene uncharacterized LOC102723543 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr1:203722055-203722656 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 2354 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 2355 Neighboring gene OCT4-NANOG hESC enhancer GRCh37_chr1:203741871-203742446 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 2356 Neighboring gene lymphocyte transmembrane adaptor 1 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 2357 Neighboring gene uncharacterized LOC128031836 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr1:203772353-203772854 Neighboring gene charged multivesicular body protein 5 pseudogene Neighboring gene zinc finger BED-type containing 6 Neighboring gene MPRA-validated peak661 silencer Neighboring gene H3K27ac hESC enhancer GRCh37_chr1:203810670-203811170 Neighboring gene ribosomal protein L35a pseudogene 5 Neighboring gene Sharpr-MPRA regulatory region 5904 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr1:203831257-203831832 Neighboring gene small nuclear ribonucleoprotein polypeptide E Neighboring gene keratin 8 pseudogene 29

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: HPA RNA-seq normal tissues HPA RNA-seq normal tissues
    • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
    • BioProject: PRJEB4337
    • Publication: PMID 24309898
    • Analysis date: Wed Apr 4 07:08:55 2018

    Bibliography

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    Related articles in PubMed

    1. Multiple nuclear-replicating viruses require the stress-induced protein ZC3H11A for efficient growth. Younis S, et al. Proc Natl Acad Sci U S A, 2018 Apr 17. PMID 29610341, Free PMC Article
    2. The RNA-binding protein ZC3H11A interacts with the nuclear poly(A)-binding protein PABPN1 and alters polyadenylation of viral transcripts. Kases K, et al. J Biol Chem, 2023 Aug. PMID 37356722, Free PMC Article
    3. Genome-wide association analysis in East Asians identifies breast cancer susceptibility loci at 1q32.1, 5q14.3 and 15q26.1. Cai Q, et al. Nat Genet, 2014 Aug. PMID 25038754, Free PMC Article
    4. The proteins PDIP3 and ZC11A associate with the human TREX complex in an ATP-dependent manner and function in mRNA export. Folco EG, et al. PLoS One, 2012. PMID 22928037, Free PMC Article
    5. Proliferating cell nuclear antigen (PCNA)-associated KIAA0101/PAF15 protein is a cell cycle-regulated anaphase-promoting complex/cyclosome substrate. Emanuele MJ, et al. Proc Natl Acad Sci U S A, 2011 Jun 14. PMID 21628590, Free PMC Article

    See all (113) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. The RNA-binding protein ZC3H11A interacts with the nuclear poly(A)-binding protein PABPN1 and alters polyadenylation of viral transcripts.
      Title: The RNA-binding protein ZC3H11A interacts with the nuclear poly(A)-binding protein PABPN1 and alters polyadenylation of viral transcripts.
    2. Knockout of ZC3H11A in HeLa cells demonstrated that several nuclear-replicating viruses are dependent on ZC3H11A for efficient growth whereas cytoplasmic replicating viruses are not. ZC3H11A binds to short purine-rich ribonucleotide stretches in cellular and adenoviral transcripts. ZC3H11A is important for maintaining nuclear export of mRNAs during stress. Several nuclear-replicating viruses take advantage of this.
      Title: Multiple nuclear-replicating viruses require the stress-induced protein ZC3H11A for efficient growth.
    3. PDIP3 and ZC11A associate with the human TREX complex in an ATP-dependent manner and function in mRNA export.
      Title: The proteins PDIP3 and ZC11A associate with the human TREX complex in an ATP-dependent manner and function in mRNA export.
    4. Observational study of gene-disease association. (HuGE Navigator)
      Title: Follow-up of a major linkage peak on chromosome 1 reveals suggestive QTLs associated with essential hypertension: GenNet study.
    Submit: New GeneRIF Correction

    Phenotypes

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    Find tests for this gene in the NIH Genetic Testing Registry (GTR)

    Review eQTL and phenotype association data in this region using PheGenI

    EBI GWAS Catalog

    Description
    Genome-wide association analysis in East Asians identifies breast cancer susceptibility loci at 1q32.1, 5q14.3 and 15q26.1.
    EBI GWAS Catalog

    Variation

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    See variants in ClinVar

    See studies and variants in dbVar

    See Variation Viewer (GRCh37.p13)

    See Variation Viewer (GRCh38)

    Genotypes

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Clone Names

    • KIAA0663, DKFZp781G2455, DKFZp686D03108, DKFZp686F14109

    Gene Ontology Provided by GOA

    Function Evidence Code Pubs
    enables RNA binding HDA PubMed 
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in poly(A)+ mRNA export from nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in poly(A)+ mRNA export from nucleus IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nucleoplasm TAS
    Traceable Author Statement
    more info
    		  
    part_of transcription export complex IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    zinc finger CCCH domain-containing protein 11A
    Names
    zinc finger CCCH-type domain containing 11A

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001319238.2 → NP_001306167.1  zinc finger CCCH domain-containing protein 11A isoform 1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longest transcript. Variants 1-7 encode the same protein (isoform 1).
      Source sequence(s)
      AC114402
      Consensus CDS
      CCDS30978.1
      UniProtKB/Swiss-Prot
      O75152, Q6AHY4, Q6AHY9, Q6AW79, Q6AWA1, Q6PJK4, Q86XZ7
      UniProtKB/TrEMBL
      B4DLG2
      Related
      ENSP00000356183.1, ENST00000367214.5
      Conserved Domains (2) summary
      pfam12287
      Location:687 → 773
      Caprin-1_C; Cytoplasmic activation/proliferation-associated protein-1 C term
      pfam15663
      Location:1 → 110
      zf-CCCH_3; Zinc-finger containing family

    2. NM_001319239.2 → NP_001306168.1  zinc finger CCCH domain-containing protein 11A isoform 1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Variants 1-7 encode the same protein (isoform 1).
      Source sequence(s)
      AC114402
      Consensus CDS
      CCDS30978.1
      UniProtKB/Swiss-Prot
      O75152, Q6AHY4, Q6AHY9, Q6AW79, Q6AWA1, Q6PJK4, Q86XZ7
      UniProtKB/TrEMBL
      B4DLG2
      Related
      ENSP00000333253.4, ENST00000332127.8
      Conserved Domains (2) summary
      pfam12287
      Location:687 → 773
      Caprin-1_C; Cytoplasmic activation/proliferation-associated protein-1 C term
      pfam15663
      Location:1 → 110
      zf-CCCH_3; Zinc-finger containing family

    3. NM_001350261.2 → NP_001337190.1  zinc finger CCCH domain-containing protein 11A isoform 1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (4) differs in the 5' UTR compared to variant 1. Variants 1-7 encode the same protein (isoform 1).
      Source sequence(s)
      AC114402
      Consensus CDS
      CCDS30978.1
      UniProtKB/Swiss-Prot
      O75152, Q6AHY4, Q6AHY9, Q6AW79, Q6AWA1, Q6PJK4, Q86XZ7
      UniProtKB/TrEMBL
      B4DLG2
      Conserved Domains (2) summary
      pfam12287
      Location:687 → 773
      Caprin-1_C; Cytoplasmic activation/proliferation-associated protein-1 C term
      pfam15663
      Location:1 → 110
      zf-CCCH_3; Zinc-finger containing family

    4. NM_001350262.2 → NP_001337191.1  zinc finger CCCH domain-containing protein 11A isoform 1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (5) differs in the 5' UTR compared to variant 1. Variants 1-7 encode the same protein (isoform 1).
      Source sequence(s)
      AC114402
      Consensus CDS
      CCDS30978.1
      UniProtKB/Swiss-Prot
      O75152, Q6AHY4, Q6AHY9, Q6AW79, Q6AWA1, Q6PJK4, Q86XZ7
      UniProtKB/TrEMBL
      B4DLG2
      Conserved Domains (2) summary
      pfam12287
      Location:687 → 773
      Caprin-1_C; Cytoplasmic activation/proliferation-associated protein-1 C term
      pfam15663
      Location:1 → 110
      zf-CCCH_3; Zinc-finger containing family

    5. NM_001350263.2 → NP_001337192.1  zinc finger CCCH domain-containing protein 11A isoform 1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (6) differs in the 5' UTR compared to variant 1. Variants 1-7 encode the same protein (isoform 1).
      Source sequence(s)
      AC114402
      Consensus CDS
      CCDS30978.1
      UniProtKB/Swiss-Prot
      O75152, Q6AHY4, Q6AHY9, Q6AW79, Q6AWA1, Q6PJK4, Q86XZ7
      UniProtKB/TrEMBL
      B4DLG2
      Conserved Domains (2) summary
      pfam12287
      Location:687 → 773
      Caprin-1_C; Cytoplasmic activation/proliferation-associated protein-1 C term
      pfam15663
      Location:1 → 110
      zf-CCCH_3; Zinc-finger containing family

    6. NM_001350264.2 → NP_001337193.1  zinc finger CCCH domain-containing protein 11A isoform 1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (7) differs in the 5' UTR compared to variant 1. Variants 1-7 encode the same protein (isoform 1).
      Source sequence(s)
      AC114402
      Consensus CDS
      CCDS30978.1
      UniProtKB/Swiss-Prot
      O75152, Q6AHY4, Q6AHY9, Q6AW79, Q6AWA1, Q6PJK4, Q86XZ7
      UniProtKB/TrEMBL
      B4DLG2
      Conserved Domains (2) summary
      pfam12287
      Location:687 → 773
      Caprin-1_C; Cytoplasmic activation/proliferation-associated protein-1 C term
      pfam15663
      Location:1 → 110
      zf-CCCH_3; Zinc-finger containing family

    7. NM_001350265.2 → NP_001337194.1  zinc finger CCCH domain-containing protein 11A isoform 2

      Status: VALIDATED

      Description
      Transcript Variant: This variant (8) differs in the 5' UTR and uses an alternate in-frame splice site in the 3' coding region. The encoded isoform (2) has the same N- and C-termini, but is two aa shorter than isoform 1. Variants 8 and 9 encode the same protein (isoform 2).
      Source sequence(s)
      AC114402
      UniProtKB/TrEMBL
      B4DLG2
      Conserved Domains (2) summary
      pfam12287
      Location:685 → 771
      Caprin-1_C; Cytoplasmic activation/proliferation-associated protein-1 C term
      pfam15663
      Location:1 → 110
      zf-CCCH_3; Zinc-finger containing family

    8. NM_001350266.2 → NP_001337195.1  zinc finger CCCH domain-containing protein 11A isoform 2

      Status: VALIDATED

      Description
      Transcript Variant: This variant (9) differs in the 5' UTR and uses an alternate in-frame splice site in the 3' coding region. The encoded isoform (2) has the same N- and C-termini, but is two aa shorter than isoform 1. Variants 8 and 9 encode the same protein (isoform 2).
      Source sequence(s)
      AC114402
      UniProtKB/TrEMBL
      B4DLG2
      Conserved Domains (2) summary
      pfam12287
      Location:685 → 771
      Caprin-1_C; Cytoplasmic activation/proliferation-associated protein-1 C term
      pfam15663
      Location:1 → 110
      zf-CCCH_3; Zinc-finger containing family

    9. NM_001376334.1 → NP_001363263.1  zinc finger CCCH domain-containing protein 11A isoform 1

      Status: VALIDATED

      Source sequence(s)
      AC114402
      Consensus CDS
      CCDS30978.1
      UniProtKB/Swiss-Prot
      O75152, Q6AHY4, Q6AHY9, Q6AW79, Q6AWA1, Q6PJK4, Q86XZ7
      UniProtKB/TrEMBL
      B4DLG2
      Conserved Domains (2) summary
      pfam12287
      Location:687 → 773
      Caprin-1_C; Cytoplasmic activation/proliferation-associated protein-1 C term
      pfam15663
      Location:1 → 110
      zf-CCCH_3; Zinc-finger containing family

    10. NM_001376335.1 → NP_001363264.1  zinc finger CCCH domain-containing protein 11A isoform 1

      Status: VALIDATED

      Source sequence(s)
      AC114402
      Consensus CDS
      CCDS30978.1
      UniProtKB/Swiss-Prot
      O75152, Q6AHY4, Q6AHY9, Q6AW79, Q6AWA1, Q6PJK4, Q86XZ7
      UniProtKB/TrEMBL
      B4DLG2
      Conserved Domains (2) summary
      pfam12287
      Location:687 → 773
      Caprin-1_C; Cytoplasmic activation/proliferation-associated protein-1 C term
      pfam15663
      Location:1 → 110
      zf-CCCH_3; Zinc-finger containing family

    11. NM_001376336.1 → NP_001363265.1  zinc finger CCCH domain-containing protein 11A isoform 1

      Status: VALIDATED

      Source sequence(s)
      AC114402
      Consensus CDS
      CCDS30978.1
      UniProtKB/Swiss-Prot
      O75152, Q6AHY4, Q6AHY9, Q6AW79, Q6AWA1, Q6PJK4, Q86XZ7
      UniProtKB/TrEMBL
      B4DLG2
      Related
      ENST00000640465.1
      Conserved Domains (2) summary
      pfam12287
      Location:687 → 773
      Caprin-1_C; Cytoplasmic activation/proliferation-associated protein-1 C term
      pfam15663
      Location:1 → 110
      zf-CCCH_3; Zinc-finger containing family

    12. NM_001376337.1 → NP_001363266.1  zinc finger CCCH domain-containing protein 11A isoform 1

      Status: VALIDATED

      Source sequence(s)
      AC114402
      Consensus CDS
      CCDS30978.1
      UniProtKB/Swiss-Prot
      O75152, Q6AHY4, Q6AHY9, Q6AW79, Q6AWA1, Q6PJK4, Q86XZ7
      UniProtKB/TrEMBL
      B4DLG2
      Conserved Domains (2) summary
      pfam12287
      Location:687 → 773
      Caprin-1_C; Cytoplasmic activation/proliferation-associated protein-1 C term
      pfam15663
      Location:1 → 110
      zf-CCCH_3; Zinc-finger containing family

    13. NM_001376338.1 → NP_001363267.1  zinc finger CCCH domain-containing protein 11A isoform 1

      Status: VALIDATED

      Source sequence(s)
      AC114402
      Consensus CDS
      CCDS30978.1
      UniProtKB/Swiss-Prot
      O75152, Q6AHY4, Q6AHY9, Q6AW79, Q6AWA1, Q6PJK4, Q86XZ7
      UniProtKB/TrEMBL
      B4DLG2
      Conserved Domains (2) summary
      pfam12287
      Location:687 → 773
      Caprin-1_C; Cytoplasmic activation/proliferation-associated protein-1 C term
      pfam15663
      Location:1 → 110
      zf-CCCH_3; Zinc-finger containing family

    14. NM_001376339.1 → NP_001363268.1  zinc finger CCCH domain-containing protein 11A isoform 1

      Status: VALIDATED

      Source sequence(s)
      AC114402
      Consensus CDS
      CCDS30978.1
      UniProtKB/Swiss-Prot
      O75152, Q6AHY4, Q6AHY9, Q6AW79, Q6AWA1, Q6PJK4, Q86XZ7
      UniProtKB/TrEMBL
      B4DLG2
      Conserved Domains (2) summary
      pfam12287
      Location:687 → 773
      Caprin-1_C; Cytoplasmic activation/proliferation-associated protein-1 C term
      pfam15663
      Location:1 → 110
      zf-CCCH_3; Zinc-finger containing family

    15. NM_001376340.1 → NP_001363269.1  zinc finger CCCH domain-containing protein 11A isoform 1

      Status: VALIDATED

      Source sequence(s)
      AC114402
      Consensus CDS
      CCDS30978.1
      UniProtKB/Swiss-Prot
      O75152, Q6AHY4, Q6AHY9, Q6AW79, Q6AWA1, Q6PJK4, Q86XZ7
      UniProtKB/TrEMBL
      B4DLG2
      Conserved Domains (2) summary
      pfam12287
      Location:687 → 773
      Caprin-1_C; Cytoplasmic activation/proliferation-associated protein-1 C term
      pfam15663
      Location:1 → 110
      zf-CCCH_3; Zinc-finger containing family

    16. NM_001376341.1 → NP_001363270.1  zinc finger CCCH domain-containing protein 11A isoform 1

      Status: VALIDATED

      Source sequence(s)
      AC114402
      Consensus CDS
      CCDS30978.1
      UniProtKB/Swiss-Prot
      O75152, Q6AHY4, Q6AHY9, Q6AW79, Q6AWA1, Q6PJK4, Q86XZ7
      UniProtKB/TrEMBL
      B4DLG2
      Conserved Domains (2) summary
      pfam12287
      Location:687 → 773
      Caprin-1_C; Cytoplasmic activation/proliferation-associated protein-1 C term
      pfam15663
      Location:1 → 110
      zf-CCCH_3; Zinc-finger containing family

    17. NM_001376342.1 → NP_001363271.1  zinc finger CCCH domain-containing protein 11A isoform 1

      Status: VALIDATED

      Source sequence(s)
      AC114402
      Consensus CDS
      CCDS30978.1
      UniProtKB/Swiss-Prot
      O75152, Q6AHY4, Q6AHY9, Q6AW79, Q6AWA1, Q6PJK4, Q86XZ7
      UniProtKB/TrEMBL
      B4DLG2
      Related
      ENSP00000356179.1, ENST00000367210.3
      Conserved Domains (2) summary
      pfam12287
      Location:687 → 773
      Caprin-1_C; Cytoplasmic activation/proliferation-associated protein-1 C term
      pfam15663
      Location:1 → 110
      zf-CCCH_3; Zinc-finger containing family

    18. NM_001376343.1 → NP_001363272.1  zinc finger CCCH domain-containing protein 11A isoform 1

      Status: VALIDATED

      Source sequence(s)
      AC114402
      Consensus CDS
      CCDS30978.1
      UniProtKB/Swiss-Prot
      O75152, Q6AHY4, Q6AHY9, Q6AW79, Q6AWA1, Q6PJK4, Q86XZ7
      UniProtKB/TrEMBL
      B4DLG2
      Conserved Domains (2) summary
      pfam12287
      Location:687 → 773
      Caprin-1_C; Cytoplasmic activation/proliferation-associated protein-1 C term
      pfam15663
      Location:1 → 110
      zf-CCCH_3; Zinc-finger containing family

    19. NM_001376344.1 → NP_001363273.1  zinc finger CCCH domain-containing protein 11A isoform 1

      Status: VALIDATED

      Source sequence(s)
      AC114402
      Consensus CDS
      CCDS30978.1
      UniProtKB/Swiss-Prot
      O75152, Q6AHY4, Q6AHY9, Q6AW79, Q6AWA1, Q6PJK4, Q86XZ7
      UniProtKB/TrEMBL
      B4DLG2
      Conserved Domains (2) summary
      pfam12287
      Location:687 → 773
      Caprin-1_C; Cytoplasmic activation/proliferation-associated protein-1 C term
      pfam15663
      Location:1 → 110
      zf-CCCH_3; Zinc-finger containing family

    20. NM_001376345.1 → NP_001363274.1  zinc finger CCCH domain-containing protein 11A isoform 1

      Status: VALIDATED

      Source sequence(s)
      AC114402
      Consensus CDS
      CCDS30978.1
      UniProtKB/Swiss-Prot
      O75152, Q6AHY4, Q6AHY9, Q6AW79, Q6AWA1, Q6PJK4, Q86XZ7
      UniProtKB/TrEMBL
      B4DLG2
      Conserved Domains (2) summary
      pfam12287
      Location:687 → 773
      Caprin-1_C; Cytoplasmic activation/proliferation-associated protein-1 C term
      pfam15663
      Location:1 → 110
      zf-CCCH_3; Zinc-finger containing family

    21. NM_001376346.1 → NP_001363275.1  zinc finger CCCH domain-containing protein 11A isoform 1

      Status: VALIDATED

      Source sequence(s)
      AC114402
      Consensus CDS
      CCDS30978.1
      UniProtKB/Swiss-Prot
      O75152, Q6AHY4, Q6AHY9, Q6AW79, Q6AWA1, Q6PJK4, Q86XZ7
      UniProtKB/TrEMBL
      B4DLG2
      Conserved Domains (2) summary
      pfam12287
      Location:687 → 773
      Caprin-1_C; Cytoplasmic activation/proliferation-associated protein-1 C term
      pfam15663
      Location:1 → 110
      zf-CCCH_3; Zinc-finger containing family

    22. NM_001376347.1 → NP_001363276.1  zinc finger CCCH domain-containing protein 11A isoform 1

      Status: VALIDATED

      Source sequence(s)
      AC114402
      Consensus CDS
      CCDS30978.1
      UniProtKB/Swiss-Prot
      O75152, Q6AHY4, Q6AHY9, Q6AW79, Q6AWA1, Q6PJK4, Q86XZ7
      UniProtKB/TrEMBL
      B4DLG2
      Conserved Domains (2) summary
      pfam12287
      Location:687 → 773
      Caprin-1_C; Cytoplasmic activation/proliferation-associated protein-1 C term
      pfam15663
      Location:1 → 110
      zf-CCCH_3; Zinc-finger containing family

    23. NM_001376348.1 → NP_001363277.1  zinc finger CCCH domain-containing protein 11A isoform 1

      Status: VALIDATED

      Source sequence(s)
      AC114402
      Consensus CDS
      CCDS30978.1
      UniProtKB/Swiss-Prot
      O75152, Q6AHY4, Q6AHY9, Q6AW79, Q6AWA1, Q6PJK4, Q86XZ7
      UniProtKB/TrEMBL
      B4DLG2
      Conserved Domains (2) summary
      pfam12287
      Location:687 → 773
      Caprin-1_C; Cytoplasmic activation/proliferation-associated protein-1 C term
      pfam15663
      Location:1 → 110
      zf-CCCH_3; Zinc-finger containing family

    24. NM_001376349.1 → NP_001363278.1  zinc finger CCCH domain-containing protein 11A isoform 1

      Status: VALIDATED

      Source sequence(s)
      AC114402
      Consensus CDS
      CCDS30978.1
      UniProtKB/Swiss-Prot
      O75152, Q6AHY4, Q6AHY9, Q6AW79, Q6AWA1, Q6PJK4, Q86XZ7
      UniProtKB/TrEMBL
      B4DLG2
      Conserved Domains (2) summary
      pfam12287
      Location:687 → 773
      Caprin-1_C; Cytoplasmic activation/proliferation-associated protein-1 C term
      pfam15663
      Location:1 → 110
      zf-CCCH_3; Zinc-finger containing family

    25. NM_001376350.1 → NP_001363279.1  zinc finger CCCH domain-containing protein 11A isoform 1

      Status: VALIDATED

      Source sequence(s)
      AC114402
      Consensus CDS
      CCDS30978.1
      UniProtKB/Swiss-Prot
      O75152, Q6AHY4, Q6AHY9, Q6AW79, Q6AWA1, Q6PJK4, Q86XZ7
      UniProtKB/TrEMBL
      B4DLG2
      Conserved Domains (2) summary
      pfam12287
      Location:687 → 773
      Caprin-1_C; Cytoplasmic activation/proliferation-associated protein-1 C term
      pfam15663
      Location:1 → 110
      zf-CCCH_3; Zinc-finger containing family

    26. NM_001376351.1 → NP_001363280.1  zinc finger CCCH domain-containing protein 11A isoform 1

      Status: VALIDATED

      Source sequence(s)
      AC114402
      Consensus CDS
      CCDS30978.1
      UniProtKB/Swiss-Prot
      O75152, Q6AHY4, Q6AHY9, Q6AW79, Q6AWA1, Q6PJK4, Q86XZ7
      UniProtKB/TrEMBL
      B4DLG2
      Conserved Domains (2) summary
      pfam12287
      Location:687 → 773
      Caprin-1_C; Cytoplasmic activation/proliferation-associated protein-1 C term
      pfam15663
      Location:1 → 110
      zf-CCCH_3; Zinc-finger containing family

    27. NM_001376352.1 → NP_001363281.1  zinc finger CCCH domain-containing protein 11A isoform 1

      Status: VALIDATED

      Source sequence(s)
      AC114402
      Consensus CDS
      CCDS30978.1
      UniProtKB/Swiss-Prot
      O75152, Q6AHY4, Q6AHY9, Q6AW79, Q6AWA1, Q6PJK4, Q86XZ7
      UniProtKB/TrEMBL
      B4DLG2
      Conserved Domains (2) summary
      pfam12287
      Location:687 → 773
      Caprin-1_C; Cytoplasmic activation/proliferation-associated protein-1 C term
      pfam15663
      Location:1 → 110
      zf-CCCH_3; Zinc-finger containing family

    28. NM_001376353.1 → NP_001363282.1  zinc finger CCCH domain-containing protein 11A isoform 1

      Status: VALIDATED

      Source sequence(s)
      AC114402
      Consensus CDS
      CCDS30978.1
      UniProtKB/Swiss-Prot
      O75152, Q6AHY4, Q6AHY9, Q6AW79, Q6AWA1, Q6PJK4, Q86XZ7
      UniProtKB/TrEMBL
      B4DLG2
      Conserved Domains (2) summary
      pfam12287
      Location:687 → 773
      Caprin-1_C; Cytoplasmic activation/proliferation-associated protein-1 C term
      pfam15663
      Location:1 → 110
      zf-CCCH_3; Zinc-finger containing family

    29. NM_001376354.1 → NP_001363283.1  zinc finger CCCH domain-containing protein 11A isoform 1

      Status: VALIDATED

      Source sequence(s)
      AC114402
      Consensus CDS
      CCDS30978.1
      UniProtKB/Swiss-Prot
      O75152, Q6AHY4, Q6AHY9, Q6AW79, Q6AWA1, Q6PJK4, Q86XZ7
      UniProtKB/TrEMBL
      B4DLG2
      Conserved Domains (2) summary
      pfam12287
      Location:687 → 773
      Caprin-1_C; Cytoplasmic activation/proliferation-associated protein-1 C term
      pfam15663
      Location:1 → 110
      zf-CCCH_3; Zinc-finger containing family

    30. NM_001376355.1 → NP_001363284.1  zinc finger CCCH domain-containing protein 11A isoform 1

      Status: VALIDATED

      Source sequence(s)
      AC114402
      Consensus CDS
      CCDS30978.1
      UniProtKB/Swiss-Prot
      O75152, Q6AHY4, Q6AHY9, Q6AW79, Q6AWA1, Q6PJK4, Q86XZ7
      UniProtKB/TrEMBL
      B4DLG2
      Conserved Domains (2) summary
      pfam12287
      Location:687 → 773
      Caprin-1_C; Cytoplasmic activation/proliferation-associated protein-1 C term
      pfam15663
      Location:1 → 110
      zf-CCCH_3; Zinc-finger containing family

    31. NM_001376356.1 → NP_001363285.1  zinc finger CCCH domain-containing protein 11A isoform 1

      Status: VALIDATED

      Source sequence(s)
      AC114402
      Consensus CDS
      CCDS30978.1
      UniProtKB/Swiss-Prot
      O75152, Q6AHY4, Q6AHY9, Q6AW79, Q6AWA1, Q6PJK4, Q86XZ7
      UniProtKB/TrEMBL
      B4DLG2
      Conserved Domains (2) summary
      pfam12287
      Location:687 → 773
      Caprin-1_C; Cytoplasmic activation/proliferation-associated protein-1 C term
      pfam15663
      Location:1 → 110
      zf-CCCH_3; Zinc-finger containing family

    32. NM_001376357.1 → NP_001363286.1  zinc finger CCCH domain-containing protein 11A isoform 1

      Status: VALIDATED

      Source sequence(s)
      AC114402
      Consensus CDS
      CCDS30978.1
      UniProtKB/Swiss-Prot
      O75152, Q6AHY4, Q6AHY9, Q6AW79, Q6AWA1, Q6PJK4, Q86XZ7
      UniProtKB/TrEMBL
      B4DLG2
      Conserved Domains (2) summary
      pfam12287
      Location:687 → 773
      Caprin-1_C; Cytoplasmic activation/proliferation-associated protein-1 C term
      pfam15663
      Location:1 → 110
      zf-CCCH_3; Zinc-finger containing family

    33. NM_001376358.1 → NP_001363287.1  zinc finger CCCH domain-containing protein 11A isoform 1

      Status: VALIDATED

      Source sequence(s)
      AC114402
      Consensus CDS
      CCDS30978.1
      UniProtKB/Swiss-Prot
      O75152, Q6AHY4, Q6AHY9, Q6AW79, Q6AWA1, Q6PJK4, Q86XZ7
      UniProtKB/TrEMBL
      B4DLG2
      Conserved Domains (2) summary
      pfam12287
      Location:687 → 773
      Caprin-1_C; Cytoplasmic activation/proliferation-associated protein-1 C term
      pfam15663
      Location:1 → 110
      zf-CCCH_3; Zinc-finger containing family

    34. NM_001376359.1 → NP_001363288.1  zinc finger CCCH domain-containing protein 11A isoform 1

      Status: VALIDATED

      Source sequence(s)
      AC114402
      Consensus CDS
      CCDS30978.1
      UniProtKB/Swiss-Prot
      O75152, Q6AHY4, Q6AHY9, Q6AW79, Q6AWA1, Q6PJK4, Q86XZ7
      UniProtKB/TrEMBL
      B4DLG2
      Conserved Domains (2) summary
      pfam12287
      Location:687 → 773
      Caprin-1_C; Cytoplasmic activation/proliferation-associated protein-1 C term
      pfam15663
      Location:1 → 110
      zf-CCCH_3; Zinc-finger containing family

    35. NM_001376360.1 → NP_001363289.1  zinc finger CCCH domain-containing protein 11A isoform 1

      Status: VALIDATED

      Source sequence(s)
      AC114402
      Consensus CDS
      CCDS30978.1
      UniProtKB/Swiss-Prot
      O75152, Q6AHY4, Q6AHY9, Q6AW79, Q6AWA1, Q6PJK4, Q86XZ7
      UniProtKB/TrEMBL
      B4DLG2
      Related
      ENSP00000491830.1, ENST00000639812.1
      Conserved Domains (2) summary
      pfam12287
      Location:687 → 773
      Caprin-1_C; Cytoplasmic activation/proliferation-associated protein-1 C term
      pfam15663
      Location:1 → 110
      zf-CCCH_3; Zinc-finger containing family

    36. NM_001376361.1 → NP_001363290.1  zinc finger CCCH domain-containing protein 11A isoform 1

      Status: VALIDATED

      Source sequence(s)
      AC114402
      Consensus CDS
      CCDS30978.1
      UniProtKB/Swiss-Prot
      O75152, Q6AHY4, Q6AHY9, Q6AW79, Q6AWA1, Q6PJK4, Q86XZ7
      UniProtKB/TrEMBL
      B4DLG2
      Conserved Domains (2) summary
      pfam12287
      Location:687 → 773
      Caprin-1_C; Cytoplasmic activation/proliferation-associated protein-1 C term
      pfam15663
      Location:1 → 110
      zf-CCCH_3; Zinc-finger containing family

    37. NM_001376362.1 → NP_001363291.1  zinc finger CCCH domain-containing protein 11A isoform 1

      Status: VALIDATED

      Source sequence(s)
      AC114402
      Consensus CDS
      CCDS30978.1
      UniProtKB/Swiss-Prot
      O75152, Q6AHY4, Q6AHY9, Q6AW79, Q6AWA1, Q6PJK4, Q86XZ7
      UniProtKB/TrEMBL
      B4DLG2
      Conserved Domains (2) summary
      pfam12287
      Location:687 → 773
      Caprin-1_C; Cytoplasmic activation/proliferation-associated protein-1 C term
      pfam15663
      Location:1 → 110
      zf-CCCH_3; Zinc-finger containing family

    38. NM_001376363.1 → NP_001363292.1  zinc finger CCCH domain-containing protein 11A isoform 1

      Status: VALIDATED

      Source sequence(s)
      AC114402
      Consensus CDS
      CCDS30978.1
      UniProtKB/Swiss-Prot
      O75152, Q6AHY4, Q6AHY9, Q6AW79, Q6AWA1, Q6PJK4, Q86XZ7
      UniProtKB/TrEMBL
      B4DLG2
      Conserved Domains (2) summary
      pfam12287
      Location:687 → 773
      Caprin-1_C; Cytoplasmic activation/proliferation-associated protein-1 C term
      pfam15663
      Location:1 → 110
      zf-CCCH_3; Zinc-finger containing family

    39. NM_001376364.1 → NP_001363293.1  zinc finger CCCH domain-containing protein 11A isoform 1

      Status: VALIDATED

      Source sequence(s)
      AC114402
      Consensus CDS
      CCDS30978.1
      UniProtKB/Swiss-Prot
      O75152, Q6AHY4, Q6AHY9, Q6AW79, Q6AWA1, Q6PJK4, Q86XZ7
      UniProtKB/TrEMBL
      B4DLG2
      Conserved Domains (2) summary
      pfam12287
      Location:687 → 773
      Caprin-1_C; Cytoplasmic activation/proliferation-associated protein-1 C term
      pfam15663
      Location:1 → 110
      zf-CCCH_3; Zinc-finger containing family

    40. NM_001376365.1 → NP_001363294.1  zinc finger CCCH domain-containing protein 11A isoform 1

      Status: VALIDATED

      Source sequence(s)
      AC114402
      Consensus CDS
      CCDS30978.1
      UniProtKB/Swiss-Prot
      O75152, Q6AHY4, Q6AHY9, Q6AW79, Q6AWA1, Q6PJK4, Q86XZ7
      UniProtKB/TrEMBL
      B4DLG2
      Conserved Domains (2) summary
      pfam12287
      Location:687 → 773
      Caprin-1_C; Cytoplasmic activation/proliferation-associated protein-1 C term
      pfam15663
      Location:1 → 110
      zf-CCCH_3; Zinc-finger containing family

    41. NM_001376366.1 → NP_001363295.1  zinc finger CCCH domain-containing protein 11A isoform 2

      Status: VALIDATED

      Source sequence(s)
      AC114402
      UniProtKB/TrEMBL
      B4DLG2
      Conserved Domains (2) summary
      pfam12287
      Location:685 → 771
      Caprin-1_C; Cytoplasmic activation/proliferation-associated protein-1 C term
      pfam15663
      Location:1 → 110
      zf-CCCH_3; Zinc-finger containing family

    42. NM_001376367.1 → NP_001363296.1  zinc finger CCCH domain-containing protein 11A isoform 2

      Status: VALIDATED

      Source sequence(s)
      AC114402
      UniProtKB/TrEMBL
      B4DLG2
      Conserved Domains (2) summary
      pfam12287
      Location:685 → 771
      Caprin-1_C; Cytoplasmic activation/proliferation-associated protein-1 C term
      pfam15663
      Location:1 → 110
      zf-CCCH_3; Zinc-finger containing family

    43. NM_014827.6 → NP_055642.3  zinc finger CCCH domain-containing protein 11A isoform 1

      See identical proteins and their annotated locations for NP_055642.3

      Status: VALIDATED

      Description
      Transcript Variant: This variant (3) differs in the 5' UTR compared to variant 1. Variants 1-7 encode the same protein (isoform 1).
      Source sequence(s)
      AC114402
      Consensus CDS
      CCDS30978.1
      UniProtKB/Swiss-Prot
      O75152, Q6AHY4, Q6AHY9, Q6AW79, Q6AWA1, Q6PJK4, Q86XZ7
      UniProtKB/TrEMBL
      B4DLG2
      Related
      ENSP00000356181.3, ENST00000367212.7
      Conserved Domains (2) summary
      pfam12287
      Location:687 → 773
      Caprin-1_C; Cytoplasmic activation/proliferation-associated protein-1 C term
      pfam15663
      Location:1 → 110
      zf-CCCH_3; Zinc-finger containing family

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000001.11 Reference GRCh38.p14 Primary Assembly

      Range
      203795623..203854124
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060925.1 Alternate T2T-CHM13v2.0

      Range
      203058813..203118077
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    O75152.3 GenPept UniProtKB/Swiss-Prot:O75152

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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