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    FAM186A family with sequence similarity 186 member A [ Homo sapiens (human) ]

    Gene ID: 121006, updated on 17-Sep-2024

    Summary

    Official Symbol
    FAM186Aprovided by HGNC
    Official Full Name
    family with sequence similarity 186 member Aprovided by HGNC
    Primary source
    HGNC:HGNC:26980
    See related
    Ensembl:ENSG00000185958 AllianceGenome:HGNC:26980
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Expression
    Restricted expression toward testis (RPKM 4.7) See more
    Orthologs
    NEW
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    Genomic context

    See FAM186A in Genome Data Viewer
    Location:
    12q13.12
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 12 NC_000012.12 (50327309..50396609, complement)
    RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 12 NC_060936.1 (50290439..50359662, complement)
    RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 12 NC_000012.11 (50721092..50790392, complement)

    Chromosome 12 - NC_000012.12Genomic Context describing neighboring genes Neighboring gene LIM domain and actin binding 1 Neighboring gene RNA, U6 small nuclear 1093, pseudogene Neighboring gene ReSE screen-validated silencer GRCh37_chr12:50666914-50667093 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 4451 Neighboring gene uncharacterized LOC107984505 Neighboring gene KIAA1586 pseudogene Neighboring gene MPRA-validated peak1729 silencer Neighboring gene ribosomal protein L26 pseudogene 33 Neighboring gene La ribonucleoprotein 4 Neighboring gene small nucleolar RNA, C/D box 133 Neighboring gene uncharacterized LOC124903127

    Genomic regions, transcripts, and products

    Expression

    • Project title: HPA RNA-seq normal tissues HPA RNA-seq normal tissues
    • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
    • BioProject: PRJEB4337
    • Publication: PMID 24309898
    • Analysis date: Wed Apr 4 07:08:55 2018

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001145475.3NP_001138947.1  protein FAM186A

      See identical proteins and their annotated locations for NP_001138947.1

      Status: VALIDATED

      Source sequence(s)
      AC090058, AC140061, AI808315, AL833333, BG206781
      Consensus CDS
      CCDS44878.1
      UniProtKB/Swiss-Prot
      A6NE01
      UniProtKB/TrEMBL
      F5GYN0
      Related
      ENSP00000329995.5, ENST00000327337.6
      Conserved Domains (2) summary
      PRK10715
      Location:12911491
      flk; flagella biosynthesis regulator; Provisional
      pfam03157
      Location:10451645
      Glutenin_hmw; High molecular weight glutenin subunit

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000012.12 Reference GRCh38.p14 Primary Assembly

      Range
      50327309..50396609 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060936.1 Alternate T2T-CHM13v2.0

      Range
      50290439..50359662 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)