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These reference sequences exist independently of genome builds. Explain
These reference sequences are curated independently of the genome
annotation cycle, so their versions may not match the RefSeq versions in the current
genome build. Identify version mismatches by comparing the version of the RefSeq in
this section to the one reported in Genomic regions,
transcripts, and products above.
Genomic
-
NG_007988.1 RefSeqGene
- Range
-
5001..79710
- Download
- GenBank, FASTA, Sequence Viewer (Graphics), LRG_236
mRNA and Protein(s)
-
NM_001202504.1 → NP_001189433.1 RNA polymerase II subunit A C-terminal domain phosphatase isoform 3
Status: REVIEWED
- Description
- Transcript Variant: This variant (3) contains an alternate 5' terminal exon compared to variant 1, resulting in translation initiation from an in-frame downstream AUG, and a shorter isoform (3, also known as FCP1a) compared to isoform 1.
- Source sequence(s)
-
AA282312, AF081287, BC047999, BC052576, BM512113, DB451780, DB517021
- UniProtKB/TrEMBL
-
K7EJD2
- Conserved Domains (3) summary
-
- TIGR02250
Location:58 → 204
- FCP1_euk; FCP1-like phosphatase, phosphatase domain
- cd00027
Location:517 → 597
- BRCT; Breast Cancer Suppressor Protein (BRCA1), carboxy-terminal domain. The BRCT domain is found within many DNA damage repair and cell cycle checkpoint proteins. The unique diversity of this domain superfamily allows BRCT modules to interact forming homo ...
- pfam09309
Location:597 → 842
- FCP1_C; FCP1, C-terminal
-
NM_001318511.2 → NP_001305440.1 RNA polymerase II subunit A C-terminal domain phosphatase isoform 4
Status: REVIEWED
- Description
- Transcript Variant: This variant (4) lacks an exon in the 3' coding region, which results in a frameshift, compared to variant 1. The encoded isoform (4) has a shorter and distinct C-terminus compared to isoform 1.
- Source sequence(s)
-
AA282312, AC021594, BC032515, BC047999, DR001939
- UniProtKB/TrEMBL
-
A0A0J9YWB6
- Related
- ENSP00000465119.1, ENST00000591598.5
- Conserved Domains (4) summary
-
- TIGR02250
Location:177 → 323
- FCP1_euk; FCP1-like phosphatase, phosphatase domain
- cd00027
Location:636 → 716
- BRCT; Breast Cancer Suppressor Protein (BRCA1), carboxy-terminal domain. The BRCT domain is found within many DNA damage repair and cell cycle checkpoint proteins. The unique diversity of this domain superfamily allows BRCT modules to interact forming homo ...
- pfam09309
Location:716 → 860
- FCP1_C; FCP1, C-terminal
- cl11404
Location:21 → 111
- Biotinyl_lipoyl_domains; Biotinyl_lipoyl_domains are present in biotin-dependent carboxylases/decarboxylases, the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases, and the H-protein of the glycine cleavage system (GCS). These domains transport CO2, acyl, ...
-
NM_004715.5 → NP_004706.3 RNA polymerase II subunit A C-terminal domain phosphatase isoform 1
See identical proteins and their annotated locations for NP_004706.3
Status: REVIEWED
- Description
- Transcript Variant: This variant (1) represents the predominant transcript, and encodes the longest isoform (1, also known as FCP1).
- Source sequence(s)
-
BC047999, BC052576, BM512113, DR001939
- Consensus CDS
-
CCDS12017.1
- UniProtKB/Swiss-Prot
- A8MY97, Q7Z644, Q96BZ1, Q9Y5B0, Q9Y6F5
- UniProtKB/TrEMBL
-
A0A0J9YWB6
- Related
- ENSP00000484525.2, ENST00000613122.5
- Conserved Domains (4) summary
-
- TIGR02250
Location:177 → 323
- FCP1_euk; FCP1-like phosphatase, phosphatase domain
- cd00027
Location:636 → 716
- BRCT; Breast Cancer Suppressor Protein (BRCA1), carboxy-terminal domain. The BRCT domain is found within many DNA damage repair and cell cycle checkpoint proteins. The unique diversity of this domain superfamily allows BRCT modules to interact forming homo ...
- pfam09309
Location:716 → 961
- FCP1_C; FCP1, C-terminal
- cl11404
Location:21 → 111
- Biotinyl_lipoyl_domains; Biotinyl_lipoyl_domains are present in biotin-dependent carboxylases/decarboxylases, the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases, and the H-protein of the glycine cleavage system (GCS). These domains transport CO2, acyl, ...
-
NM_048368.4 → NP_430255.2 RNA polymerase II subunit A C-terminal domain phosphatase isoform 2
See identical proteins and their annotated locations for NP_430255.2
Status: REVIEWED
- Description
- Transcript Variant: This variant (2) is missing a coding exon in the 3' region compared to variant 1. This results in a frame-shift and a shorter isoform (2, also known as FCP1b) with a distinct C-terminus (lacking the carboxy-terminal TFIIF-binding protein domain) compared to isoform 1.
- Source sequence(s)
-
AA282312, AC021594, BC047999, BC052576, BM512113, DR001939
- Consensus CDS
-
CCDS12018.1
- UniProtKB/TrEMBL
-
A0A0J9YWB6
- Related
- ENSP00000075430.7, ENST00000075430.11
- Conserved Domains (4) summary
-
- TIGR02250
Location:177 → 323
- FCP1_euk; FCP1-like phosphatase, phosphatase domain
- cd00027
Location:636 → 716
- BRCT; Breast Cancer Suppressor Protein (BRCA1), carboxy-terminal domain. The BRCT domain is found within many DNA damage repair and cell cycle checkpoint proteins. The unique diversity of this domain superfamily allows BRCT modules to interact forming homo ...
- pfam09309
Location:716 → 806
- FCP1_C; FCP1, C-terminal
- cl11404
Location:21 → 111
- Biotinyl_lipoyl_domains; Biotinyl_lipoyl_domains are present in biotin-dependent carboxylases/decarboxylases, the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases, and the H-protein of the glycine cleavage system (GCS). These domains transport CO2, acyl, ...
The following sections contain reference sequences that belong to a
specific genome build. Explain
This section includes genomic Reference
Sequences (RefSeqs) from all assemblies on which this gene is annotated, such as
RefSeqs for chromosomes and scaffolds (contigs) from both reference and alternate
assemblies. Model RNAs and proteins are also reported here.
Reference GRCh38.p14 Primary Assembly
Genomic
-
NC_000018.10 Reference GRCh38.p14 Primary Assembly
- Range
-
79676768..79756625
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
mRNA and Protein(s)
-
XM_047437924.1 → XP_047293880.1 RNA polymerase II subunit A C-terminal domain phosphatase isoform X5
- UniProtKB/TrEMBL
-
K7EJD2
-
XM_047437922.1 → XP_047293878.1 RNA polymerase II subunit A C-terminal domain phosphatase isoform X2
- UniProtKB/TrEMBL
-
K7EJD2
-
XM_047437926.1 → XP_047293882.1 RNA polymerase II subunit A C-terminal domain phosphatase isoform X6
- UniProtKB/TrEMBL
-
A0A0J9YWJ4
-
XM_011526261.2 → XP_011524563.1 RNA polymerase II subunit A C-terminal domain phosphatase isoform X4
- UniProtKB/TrEMBL
-
A0A0J9YWB6
- Conserved Domains (4) summary
-
- TIGR02250
Location:177 → 323
- FCP1_euk; FCP1-like phosphatase, phosphatase domain
- cd00027
Location:636 → 716
- BRCT; Breast Cancer Suppressor Protein (BRCA1), carboxy-terminal domain. The BRCT domain is found within many DNA damage repair and cell cycle checkpoint proteins. The unique diversity of this domain superfamily allows BRCT modules to interact forming homo ...
- pfam09309
Location:716 → 851
- FCP1_C; FCP1, C-terminal
- cl11404
Location:21 → 111
- Biotinyl_lipoyl_domains; Biotinyl_lipoyl_domains are present in biotin-dependent carboxylases/decarboxylases, the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases, and the H-protein of the glycine cleavage system (GCS). These domains transport CO2, acyl, ...
-
XM_047437925.1 → XP_047293881.1 RNA polymerase II subunit A C-terminal domain phosphatase isoform X5
- UniProtKB/TrEMBL
-
K7EJD2
-
XM_047437923.1 → XP_047293879.1 RNA polymerase II subunit A C-terminal domain phosphatase isoform X3
- UniProtKB/TrEMBL
-
K7EJD2
-
XM_047437921.1 → XP_047293877.1 RNA polymerase II subunit A C-terminal domain phosphatase isoform X1
- UniProtKB/TrEMBL
-
K7EJD2
-
XM_047437927.1 → XP_047293883.1 RNA polymerase II subunit A C-terminal domain phosphatase isoform X7
- UniProtKB/TrEMBL
-
A0A0J9YWJ4
-
XM_017026078.2 → XP_016881567.1 RNA polymerase II subunit A C-terminal domain phosphatase isoform X8
- UniProtKB/TrEMBL
-
K7EJD2
Reference GRCh38.p14 ALT_REF_LOCI_1
Genomic
-
NT_187617.1 Reference GRCh38.p14 ALT_REF_LOCI_1
- Range
-
122436..160679
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
Alternate T2T-CHM13v2.0
Genomic
-
NC_060942.1 Alternate T2T-CHM13v2.0
- Range
-
79950566..80031824
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
mRNA and Protein(s)
-
XM_054319348.1 → XP_054175323.1 RNA polymerase II subunit A C-terminal domain phosphatase isoform X5
- UniProtKB/TrEMBL
-
K7EJD2
-
XM_054319345.1 → XP_054175320.1 RNA polymerase II subunit A C-terminal domain phosphatase isoform X2
- UniProtKB/TrEMBL
-
K7EJD2
-
XM_054319350.1 → XP_054175325.1 RNA polymerase II subunit A C-terminal domain phosphatase isoform X6
- UniProtKB/TrEMBL
-
A0A0J9YWJ4
-
XM_054319347.1 → XP_054175322.1 RNA polymerase II subunit A C-terminal domain phosphatase isoform X4
- UniProtKB/TrEMBL
-
A0A0J9YWB6
-
XM_054319349.1 → XP_054175324.1 RNA polymerase II subunit A C-terminal domain phosphatase isoform X5
- UniProtKB/TrEMBL
-
K7EJD2
-
XM_054319346.1 → XP_054175321.1 RNA polymerase II subunit A C-terminal domain phosphatase isoform X3
- UniProtKB/TrEMBL
-
K7EJD2
-
XM_054319351.1 → XP_054175326.1 RNA polymerase II subunit A C-terminal domain phosphatase isoform X7
- UniProtKB/TrEMBL
-
A0A0J9YWJ4
-
XM_054319344.1 → XP_054175319.1 RNA polymerase II subunit A C-terminal domain phosphatase isoform X5
- UniProtKB/TrEMBL
-
K7EJD2
-
XM_054319352.1 → XP_054175327.1 RNA polymerase II subunit A C-terminal domain phosphatase isoform X8
- UniProtKB/TrEMBL
-
K7EJD2