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These reference sequences exist independently of genome builds. Explain
These reference sequences are curated independently of the genome
annotation cycle, so their versions may not match the RefSeq versions in the current
genome build. Identify version mismatches by comparing the version of the RefSeq in
this section to the one reported in Genomic regions,
transcripts, and products above.
Genomic
-
NG_012049.1 RefSeqGene
- Range
-
5001..68452
- Download
- GenBank, FASTA, Sequence Viewer (Graphics), LRG_139
mRNA and Protein(s)
-
NM_000562.3 → NP_000553.1 complement component C8 alpha chain preproprotein
See identical proteins and their annotated locations for NP_000553.1
Status: REVIEWED
- Source sequence(s)
-
AL121998, M16974
- Consensus CDS
-
CCDS606.1
- UniProtKB/Swiss-Prot
- A2RUI4, A2RUI5, P07357, Q13668, Q9H130
- UniProtKB/TrEMBL
-
A0A8Q3WL79
- Related
- ENSP00000354458.3, ENST00000361249.4
- Conserved Domains (3) summary
-
- smart00209
Location:551 → 584
- TSP1; Thrombospondin type 1 repeats
- smart00457
Location:289 → 492
- MACPF; membrane-attack complex / perforin
- cd00112
Location:96 → 130
- LDLa; Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about ...
The following sections contain reference sequences that belong to a
specific genome build. Explain
This section includes genomic Reference
Sequences (RefSeqs) from all assemblies on which this gene is annotated, such as
RefSeqs for chromosomes and scaffolds (contigs) from both reference and alternate
assemblies. Model RNAs and proteins are also reported here.
Reference GRCh38.p14 Primary Assembly
Genomic
-
NC_000001.11 Reference GRCh38.p14 Primary Assembly
- Range
-
56854797..56918223
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
mRNA and Protein(s)
-
XM_017002234.2 → XP_016857723.1 complement component C8 alpha chain isoform X1
- UniProtKB/TrEMBL
-
A0A8Q3WKQ2
-
XM_011542079.3 → XP_011540381.1 complement component C8 alpha chain isoform X2
- UniProtKB/TrEMBL
-
A0A8Q3WKQ2
- Related
- ENSP00000512121.1, ENST00000695723.1
- Conserved Domains (2) summary
-
- cd00112
Location:96 → 130
- LDLa; Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about ...
- cl02616
Location:289 → 366
- MACPF; MAC/Perforin domain
Alternate T2T-CHM13v2.0
Genomic
-
NC_060925.1 Alternate T2T-CHM13v2.0
- Range
-
56733342..56796778
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
mRNA and Protein(s)
-
XM_054338607.1 → XP_054194582.1 complement component C8 alpha chain isoform X1
- UniProtKB/TrEMBL
-
A0A8Q3WKQ2
-
XM_054338608.1 → XP_054194583.1 complement component C8 alpha chain isoform X2
- UniProtKB/TrEMBL
-
A0A8Q3WKQ2