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    Btnl12 butyrophilin-like 12 [ Mus musculus (house mouse) ]

    Gene ID: 102639802, updated on 17-Aug-2024

    Summary

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    Official Symbol
    Btnl12provided by MGI
    Official Full Name
    butyrophilin-like 12provided by MGI
    Primary source
    MGI:MGI:5595187
    See related
    Ensembl:ENSMUSG00000108763 AllianceGenome:MGI:5595187
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Gm36028
    Summary
    Predicted to enable signaling receptor binding activity. Predicted to be involved in T cell receptor signaling pathway and regulation of cytokine production. Predicted to be active in external side of plasma membrane. [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Low expression observed in reference dataset See more
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    Genomic context

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    See Btnl12 in Genome Data Viewer
    Location:
    16 B3; 16
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 16 NC_000082.7 (37671268..37681552, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 16 NC_000082.6 (37850904..37865237, complement)

    Chromosome 16 - NC_000082.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 46547 Neighboring gene STARR-seq mESC enhancer starr_40793 Neighboring gene STARR-seq mESC enhancer starr_40795 Neighboring gene follistatin-like 1 Neighboring gene STARR-seq mESC enhancer starr_40798 Neighboring gene predicted gene, 41452 Neighboring gene VISTA enhancer mm1361 Neighboring gene leucine rich repeat containing 58 Neighboring gene actin, beta, cytoplasmic (Actb) pseudogene Neighboring gene STARR-seq mESC enhancer starr_40799 Neighboring gene G protein-coupled receptor 156 Neighboring gene CapStarr-seq enhancer MGSCv37_chr16:37963429-37963630 Neighboring gene predicted gene, 36225 Neighboring gene predicted gene, 25140

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. Zambrowicz BP, et al. Proc Natl Acad Sci U S A, 2003 Nov 25. PMID 14610273, Free PMC Article
    2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables signaling receptor binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in T cell receptor signaling pathway IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in regulation of cytokine production IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in external side of plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein LOC102639802

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001370898.1 → NP_001357827.1  uncharacterized protein LOC102639802 precursor

      Status: VALIDATED

      Source sequence(s)
      AC161268
      UniProtKB/TrEMBL
      A0A0U1RPM1
      Related
      ENSMUSP00000146040.2, ENSMUST00000205931.2
      Conserved Domains (1) summary
      cl11960
      Location:82 → 148
      Ig; Immunoglobulin domain

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000082.7 Reference GRCm39 C57BL/6J

      Range
      37671268..37681552 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein
    Heading Accession and Version

    Gene LinkOut

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    Research Materials