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    PRAC1 PRAC1 small nuclear protein [ Homo sapiens (human) ]

    Gene ID: 84366, updated on 9-Dec-2024

    Summary

    Official Symbol
    PRAC1provided by HGNC
    Official Full Name
    PRAC1 small nuclear proteinprovided by HGNC
    Primary source
    HGNC:HGNC:30591
    See related
    Ensembl:ENSG00000159182 MIM:609819; AllianceGenome:HGNC:30591
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    PRAC; C17orf92
    Summary
    This gene is reported to be specifically expressed in prostate, rectum and distal colon. Sequence analysis suggests that it may play a regulatory role in the nucleus. [provided by RefSeq, Jul 2008]
    Expression
    Biased expression in colon (RPKM 46.5) and prostate (RPKM 34.0) See more
    Orthologs
    NEW
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    Genomic context

    See PRAC1 in Genome Data Viewer
    Location:
    17q21.32
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 17 NC_000017.11 (48721719..48722518, complement)
    RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 17 NC_060941.1 (49585320..49586119, complement)
    RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 17 NC_000017.10 (46799081..46799880, complement)

    Chromosome 17 - NC_000017.11Genomic Context describing neighboring genes Neighboring gene long intergenic non-protein coding RNA 2086 Neighboring gene ribosomal protein L9 pseudogene 28 Neighboring gene ReSE screen-validated silencer GRCh37_chr17:46790297-46790470 Neighboring gene cytochrome c oxidase subunit 6B1 pseudogene 2 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr17:46799826-46800340 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr17:46800341-46800856 Neighboring gene PRAC2 small nuclear protein Neighboring gene microRNA 3185 Neighboring gene homeobox B13

    Genomic regions, transcripts, and products

    Expression

    • Project title: HPA RNA-seq normal tissues
    • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
    • BioProject: PRJEB4337
    • Publication: PMID 24309898
    • Analysis date: Wed Apr 4 07:08:55 2018

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    General protein information

    Preferred Names
    small nuclear protein PRAC1
    Names
    prostate cancer susceptibility candidate 1
    prostate cancer susceptibility candidate protein 1
    prostate, rectum and colon expressed gene protein
    small nuclear protein PRAC

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_032391.3NP_115767.1  small nuclear protein PRAC1

      See identical proteins and their annotated locations for NP_115767.1

      Status: REVIEWED

      Source sequence(s)
      AF331165, BC030950
      Consensus CDS
      CCDS11535.1
      UniProtKB/Swiss-Prot
      Q96KF2
      Related
      ENSP00000290294.3, ENST00000290294.5

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000017.11 Reference GRCh38.p14 Primary Assembly

      Range
      48721719..48722518 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060941.1 Alternate T2T-CHM13v2.0

      Range
      49585320..49586119 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)